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1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo-

CAS No.
906147-24-8
Chemical Name:
1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo-
Synonyms
PTK7/β-catenin-IN-1;1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo-;N-([1,1'-biphenyl]-2-yl)-2-(1H-indol-3-yl)-2-oxoacetamide
CBNumber:
CB09963595
Molecular Formula:
C22H16N2O2
Molecular Weight:
340.37
MDL Number:
MOL File:
906147-24-8.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:33

1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo- Properties

Density 1.310±0.06 g/cm3(Predicted)
pka 11.25±0.70(Predicted)
form Solid

1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0998006 PTK7/β-catenin-IN-1 99.99% 906147-24-8 5mg $471 2026-06-04 Buy
ChemScene CS-0998006 PTK7/β-catenin-IN-1 99.99% 906147-24-8 10mg $758 2026-06-04 Buy
aablocks AA01LQYG PTK7/β-catenin-IN-1 >98% 906147-24-8 5mg $519 2026-05-30 Buy
aablocks AA01LQYG PTK7/β-catenin-IN-1 >98% 906147-24-8 10mg $813 2026-05-30 Buy
Arctom HY-160488 PTK7/β-catenin-IN-1 99.99% 906147-24-8 5mg $608 2026-05-26 Buy
Product number Packaging Price Buy
CS-0998006 5mg $471 Buy
CS-0998006 10mg $758 Buy
AA01LQYG 5mg $519 Buy
AA01LQYG 10mg $813 Buy
HY-160488 5mg $608 Buy

1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo- Chemical Properties, Uses, Production

Uses

PTK7/β-catenin-IN-1 (compound 01065) is a potent PTK7/β-catenin inhibitor with an IC50 of 8.9 μM and 56.5 μM for PTK7/β-catenin and p53/MDM2, respectively. PTK7/β-catenin-IN-1 has the potential for cancer research[1].

References

[1] Laetitia Ganier, et al. Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer. ACS Chem Biol. 2022 May 20;17(5):1061-1072. DOI:10.1021/acschembio.1c00826

1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo- Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4859 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 5000 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai Qianhao Biotechnology Co., LTD 13524877553 13524877553@163.com China 122 58
ChemShuttle, Inc. 83588313 18800520310 sales@chemshuttle.com China 4999 58
1H-Indole-3-acetamide, N-[1,1'-biphenyl]-2-yl-α-oxo- PTK7/β-catenin-IN-1 N-([1,1'-biphenyl]-2-yl)-2-(1H-indol-3-yl)-2-oxoacetamide 906147-24-8