4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine
- CAS No.
- 50609-01-3
- Chemical Name:
- 4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine
- Synonyms
- )ethoxy]aniL;4-[2-(1-PyrroL;4-(2-(Pyrrolidin-1-yl);4-(2-Pyrrolidinoethoxy)aniline;4-(2-(PYRROLIDIN-1-YL)ETHOXY)ANILINE;4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine;BenzenaMine, 4-[2-(1-pyrrolidinyl)ethoxy]-
- CBNumber:
- CB11010449
- Molecular Formula:
- C12H18N2O
- Molecular Weight:
- 206.28
- MDL Number:
- MFCD07790198
- MOL File:
- 50609-01-3.mol
- MSDS File:
- SDS
| Boiling point | 362.2±22.0 °C(Predicted) |
|---|---|
| Density | 1.097±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 9.76±0.20(Predicted) |
| Appearance | Light brown to brown Oil |
| InChI | InChI=1S/C12H18N2O/c13-11-3-5-12(6-4-11)15-10-9-14-7-1-2-8-14/h3-6H,1-2,7-10,13H2 |
| InChIKey | OTYZNDKWNPQQJP-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=C(OCCN2CCCC2)C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() ![]() GHS08,GHS05,GHS09,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H351-H318-H317-H400-H301-H341-H311-H331 |
| Precautionary statements | P273-P391-P501-P264-P270-P301+P310-P321-P330-P405-P501-P201-P202-P281-P308+P313-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501-P280-P305+P351+P338-P310-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P201-P202-P281-P308+P313-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501 |
| HazardClass | IRRITANT |
| HS Code | 2921410090 |
4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR302272 | 4-(2-(Pyrrolidin-1-yl)ethoxy)aniline 95% | 50609-01-3 | 100mg | $43 | 2026-06-04 | Buy |
| Apolloscientific | OR302272 | 4-(2-(Pyrrolidin-1-yl)ethoxy)aniline 95% | 50609-01-3 | 250mg | $64 | 2026-06-04 | Buy |
| Apolloscientific | OR302272 | 4-(2-(Pyrrolidin-1-yl)ethoxy)aniline 95% | 50609-01-3 | 1g | $158 | 2026-06-04 | Buy |
| Apolloscientific | OR302272 | 4-(2-(Pyrrolidin-1-yl)ethoxy)aniline 95% | 50609-01-3 | 5g | $519 | 2026-06-04 | Buy |
| Apolloscientific | OR302272 | 4-(2-(Pyrrolidin-1-yl)ethoxy)aniline 95% | 50609-01-3 | 25g | $2488 | 2026-06-04 | Buy |
4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine Chemical Properties, Uses, Production
Synthesis
265654-77-1
50609-01-3
General procedure for the synthesis of 4-[2-(pyrrolidin-1-yl)ethoxy]aniline from 1-(2-(4-nitrophenoxy)ethyl)pyrrolidine: 1-[2-(4-nitrophenoxy)ethyl]pyrrolidine (purchased from CombiBlocks, LLC, 5.00 g, 0.0212 mol) was dissolved in 100 mL of methanol and 0.5 g of 10% Pd/C catalyst, and the hydrogenation reaction was carried out under a hydrogen atmosphere (using a balloon to provide hydrogen pressure) and the reaction continued overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to dryness, the resulting product was used directly in the next step of the reaction without further purification (Yield: 4.36 g, Yield: 99.88%). Spectral analysis of the product showed LCMS (M + H) 207.4.
References
[1] Patent: WO2009/64835, 2009, A1. Location in patent: Page/Page column 168
[2] Patent: WO2004/26823, 2004, A1. Location in patent: Page 36
[3] Patent: WO2016/34642, 2016, A1. Location in patent: Page/Page column 35
[4] Patent: US2015/336982, 2015, A1. Location in patent: Paragraph 0155; 0157
[5] Journal of Organic Chemistry, 1951, vol. 16, p. 1421,1424
4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Nanjing JinruiJiuAn Biotechnology Co., Ltd. | 025-58196018 800028039 | sales@fartop.net | China | 2227 | 55 |
| Chem-Stone Co.,Ltd. | 020-82185713,82185709 13418171485 | sales@chem-stone.com | China | 743 | 56 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9849 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Porse Fine Chemical Co.,LTD | 20-66003216 18666003216 | info@porsefinechemical.com | China | 1963 | 62 |
| Taizhou Yikang Chemical Co., Ltd. | 0576-88501337 18057652630 | sales@yikangchemicals.com | China | 272 | 58 |
View Latest Price from 4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-08 | [4-[2-(Pyrrolidin-1-yl)ethoxy]phenyl]amine
50609-01-3
|
1kg | 99% | 1 | Jinan Ruitong Biotech Co., Ltd. |
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![[4-[2-(Pyrrolidin-1-yl)ethoxy]phenyl]amine pictures](/ProductImageEN1/2025-08/Small/4a8715f2-7876-4897-978b-57fbbd97bab2.gif)
- [4-[2-(Pyrrolidin-1-yl)ethoxy]phenyl]amine
50609-01-3
- 99%
- Jinan Ruitong Biotech Co., Ltd.
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