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GHRP-2

GHRP-2 Structure
GHRP-2 structure
CAS No.
158861-67-7
Chemical Name:
GHRP-2
Synonyms
GHRP-2;GHRP-2 ACETATE;GHRP;PRALMORELIN;CHRP-2;GHCA;EIF3A;d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide;-2;p-ERK1
CBNumber:
CB1104514
Molecular Formula:
C45H55N9O6
Molecular Weight:
817.98
MDL Number:
MFCD00674876
MOL File:
158861-67-7.mol
TDS File:
TDS
Last updated:2026-09-10 18:53:57
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GHRP-2 Properties

Melting point 149 - 151°C
Boiling point 1265.3±65.0 °C(Predicted)
Density 1.270±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO (Slightly, Sonicated), Water (Slightly)
form lyophilized powder
pka 13.40±0.46(Predicted)
color white to beige
Stability Hygroscopic
InChIKey HRNLPPBUBKMZMT-RDRUQFPZSA-N
SMILES C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1=CC=C2C(=C1)C=CC=C2)NC(=O)[C@@H](C)N
CAS DataBase Reference 158861-67-7(CAS DataBase Reference)
FDA UNII E6S6E1F19M
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  3
Storage Class 11 - Combustible Solids

GHRP-2 price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2056 Pralmorelin trifluoroacetate salt ≥97% (HPLC) 158861-67-7 1MG $162 2023-01-07 Buy
Sigma-Aldrich SML2056 Pralmorelin trifluoroacetate salt ≥97% (HPLC) 158861-67-7 5MG $650 2023-01-07 Buy
Usbiological 561289 EIF3A PurifiedbyProteinGaffinitychromatography. 50ug $509 2026-06-03 Buy
Usbiological 561289 EIF3A PurifiedbyProteinGaffinitychromatography. 100ug $708 2026-06-03 Buy
Usbiological 522576 EIF3A Purifiedbyimmunoaffinitychromatography. 100ul $736 2026-06-03 Buy
Product number Packaging Price Buy
SML2056 1MG $162 Buy
SML2056 5MG $650 Buy
561289 50ug $509 Buy
561289 100ug $708 Buy
522576 100ul $736 Buy

GHRP-2 Chemical Properties, Uses, Production

Description

Pralmorelin (also known as KP-102, GPA-748, GHRP-2, and Growth Hormone Releasing Peptide-2)  is a potent GH secretagogue in development as a diagnostic agent for growth hormone deficiency and for the treatment of pituitary disorders and GH deficiency. It acts as signal molecules that are involved in the control of cell growth and differentiation.

Uses

Growth hormone releasing factor. Pralmorelin is a growth hormone secretagogue that acts on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone release.

Definition

ChEBI: Pralmorelin is an oligopeptide.

benefits

Regulation of blood pressure, increased strength and healing, reduced injury, increased cell rejuvenation, increase in lean muscle mass and stronger bones.

Biochem/physiol Actions

Pralmorelin, also known as Growth hormone-releasing peptide 2 or GHRP-2, is an orally-active, synthetic peptide analogue of met-enkephalin that acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to selectively stimulate the ghrelin receptor and cause growth hormone release. Pralmorelin (GHRP-2) has been used clinically for the assessment of growth hormone deficiency (GHD), It has also been shown to have anti-inflammatory activity.

Mechanism of action

GHRP-2 is an agonist of ghrelin, a gut peptide and also known as “the hunger hormone”, which binds to the growth hormone secretagogue receptor. Pralmorelin works to enhance natural growth hormone production in two ways. First, the GHRP-2 intensifies the natural growth hormone releasing signal, resulting in a substantial secretion of growth hormone. Second, it suppresses a hormone in the body called somatostatin, also known as growth hormone inhibiting hormone (GHIH). Somatostatin generates the body to decrease its natural growth hormone production. By restricting the activity of somatostatin, GHRP-2 can improve growth hormone creation, resulting in increased natural growth hormone levels. GHRP-2 also activates ghrelin, a peptide hormone produced in the gastrointestinal system, which has strong effects on growth hormone production and appetite.

Side effects

No side effects or toxicities were observed. Thus, GHRP-2 is well tolerated and can stimulate GH secretion. Formulations or routes of administration that allow for a longer duration of action will likely be needed to use GHRP-2 in therapy[1].

Description

Growth Hormone Releasing Peptide-2 Synthetic is a single, non-glycosylated polypeptide chain containing 6 amino acids, having a molecular mass of 817.9 Dalton and a Molecular formula of C45H55N9O6.

Background

GH-releasing peptides (GHRPs) are synthetic peptides that like GHRH act directly on pituitary somatotrophs to stimulate GH release. GHRP-2, an investigational drug, is one of the most potent members of the GHRP family. It has been shown to be effective in adults via the oral and intranasal as well as the iv route of administration.

References

[1] V Mericq. “Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children.” Journal of Clinical Endocrinology & Metabolism 83 7 (1998): 2355–60.

GHRP-2 Preparation Products And Raw materials

Raw materials

Preparation Products

GHRP-2 Suppliers

Global Suppliers ( 305)
Supplier Tel Email Country ProdList Advantage
Pearl Biotechnology (Liaocheng City) Co., Ltd. 17763511183 2577248552@qq.com China 396 58
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Cellmano Biotech Limited 0551-65326643 18156095617 info@cellmano.com China 1010 55
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973 sales@uhnshanghai.com China 997 58
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810 18652991625 sales@sunlidabio.com China 3223 55
Shanghai Meishui Chemical Technology Co., Ltd 021-60549325 18616193163 China 4518 56
Supplier Advantage
Pearl Biotechnology (Liaocheng City) Co., Ltd. 58
LGM Pharma 70
Chemsky（shanghai）International Co.,Ltd. 50
Cellmano Biotech Limited 55
Hangzhou Sage Chemical Co., Ltd. 58
Beijing HuaMeiHuLiBiological Chemical 58
UHN Shanghai Research & Development Co., Ltd. 58
Shanghai Tauto Biotech Co., Ltd. 66
Nanjing Sunlida Biological Technology Co., Ltd. 55
Shanghai Meishui Chemical Technology Co., Ltd 56

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View Latest Price from GHRP-2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GHRP-2 Acetate pictures 2026-09-18 GHRP-2 Acetate
$24.00-26.00 1kit 99.99% 1000000 kit Yiwu Qitai Trading Co., Ltd.
GHRP-2 pictures 2026-09-17 GHRP-2
158861-67-7
 50mg 99% 100000 KG Yiwu Huixian Trading Co., Ltd
GHRP-2 pictures 2026-09-17 GHRP-2
158861-67-7
 $5.00 1box 99.99% 10000 bottles Hebei Jiafan Trading Company Limited
  • GHRP-2 pictures
  • GHRP-2
    158861-67-7
  • 99%
  • Yiwu Huixian Trading Co., Ltd
  • GHRP-2 pictures
  • GHRP-2
    158861-67-7
  • $5.00
  • 99.99%
  • Hebei Jiafan Trading Company Limited

GHRP-2 Spectrum

Pralmorelin(158861-67-7)1HNMR

158861-67-7 (GHRP-2) Related Search:

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d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide L-Lysinamide, D-alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl- D-ALA-D-NAL(2)-ALA-TRP-D-PHE-LYS-NH2 ACETATE SALT D-ALA-BETA-(2-NAPHTHYL)-D-ALA-TRP-D-PHE-LYS AMIDE D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2 (DES-ALA3,D-ALA1,D-2-NAL2)-GHRP-6 (DES-ALA3)-GHRP-2 (DES-ALA3)-GROWTH HORMONE-RELEASING PEPTIDE-2 (DES-ALA3)-KP-102 (DES-ALA3)-PRALMORELIN (DES-ALA8,D-ALA6,D-2-NAL7,D-PHE10)-ALPHA-MSH (6-11) AMIDE H-D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2 H-D-ALA-D-2-NAL-TRP-D-PHE-LYS-NH2 H-D-ALA-D-ALA(2-NAPHTHYL)-TRP-D-PHE-LYS-NH2 GHRP-2 GROWTH HORMONE RELEASING PROTEIN-2 (D-ALA1,D-2-NAL2)-GHRP-6 TRIFLUOROACETATE SALT D-ala-B-(2-naphthyl)-D-ala-trp-D-phe-*lys amide -2 (Tetrahydro-2H-pyran-4-yl)methoxy=pyrimidine-4-carboxylic acid npvp npvp npvp apvp replacement China supplier npvp manufacturer npvp Crystal Skype:sale8_120 Pralmorelin GHRP-2 Monoclonal Anti-MAP Kinase, Activated/monophosphorylated (Phosphothreonine ERK-1& Growth Hormone Releasing Factor (GHRF)-2 GHRP-2 (Growth Hormone Releasing Peptide) GHCA D-ALANYL-3-(2-NAPHTHALENYL)-D-ALANYL-L-ALANYL-L-TRYPTOPHYL-D-PHENYLALANYL-L-LYSINAMIDE ACETATE ADDUCT GHRP-2 (FREE PEPTIDE) (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide D-Ala-bata-(2-naphthyl)-D-Ala-Trp-D-Phe-Lys amide D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2 4-dichloro-1 8-naphthyridine 3-d]pyriMidine TFA 2-trifluoroethyl)thiazole 5-(Tributylstannyl)-2-(2 3-a]pyrazine-3 4]triazolo[4 6-dihydro-[1 7-tert-butyl 3-ethyl 5 7-naphthyridine-3 7-tert-butyl 3-Methyl 5 4]triazine-6-carboxylate ethyl 4-chloropyrrolo[1 tert-butyl 3-Methoxy-5 2-trifluoroethyl)cyclopropyl)stannane Tributyl(2-(2 CHRP-2 Growth HorMone Releasing Hexapeptide-2 Monoclonal Anti-MAP Kinase, Activated (Diphosphorylated ERK-1& EIF3A GH secretagogue receptor GH-releasing peptide receptor GHS receptor Acetic acid ghrelin -2 IL-13R&alpha Laminin &gamma