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Cetrorelix

Cetrorelix Structure
Cetrorelix structure
CAS No.
120287-85-6
Chemical Name:
Cetrorelix
Synonyms
CETRORELIX;Cetrorelixum;CETRORELIX;CETRORELIX ACID;Unii-oon1hfz4ba;Cetrorelixum [inn-latin];CETRIZINEDIHYDROCHLORIDE;Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2;Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2;AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH
CBNumber:
CB0316370
Molecular Formula:
C70H92ClN17O14
Molecular Weight:
1431.04
MDL Number:
MFCD00884467
MOL File:
120287-85-6.mol
MSDS File:
SDS
Last updated:2026-08-04 11:17:55
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Cetrorelix Properties

Melting point >259°C (dec.)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly, Heated), Methanol (Very Slightly)
form Solid
pka 9.82±0.15(Predicted)
color White to Off-White
InChIKey SBNPWPIBESPSIF-MHWMIDJBSA-N
FDA UNII OON1HFZ4BA

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H360
Hazardous Substances Data 120287-85-6(Hazardous Substances Data)

Cetrorelix price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0012400 Cetrorelix 99.71% 120287-85-6 1mg $54 2026-06-04 Buy
ChemScene CS-0012400 Cetrorelix 99.71% 120287-85-6 5mg $103 2026-06-04 Buy
ChemScene CS-0012400 Cetrorelix 99.71% 120287-85-6 10mg $162 2026-06-04 Buy
ChemScene CS-0012400 Cetrorelix 99.71% 120287-85-6 25mg $347 2026-06-04 Buy
ChemScene CS-0012400 Cetrorelix 99.71% 120287-85-6 50mg $555 2026-06-04 Buy
Product number Packaging Price Buy
CS-0012400 1mg $54 Buy
CS-0012400 5mg $103 Buy
CS-0012400 10mg $162 Buy
CS-0012400 25mg $347 Buy
CS-0012400 50mg $555 Buy

Cetrorelix Chemical Properties, Uses, Production

Description

Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.

Originator

Asta Medica (Germany)

Uses

Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.

Definition

ChEBI: Cetrorelix is a synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-tyrosyl, N(5)-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent.

Indications

Cetrorelix is used to delay your ovaries from releasing eggs too early (ovulation). It is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.

brand name

Cetrotide (Serono).

Side effects

Cetrorelix is usually administered by subcutaneous injection. The most common side effects include: pain, itching, swelling, discolouration or redness near the injection site; nausea and headache. Other possible effects may include: abdominal or stomach pain, reduced urine output, diarrhoea, indigestion, weight gain, pelvic pain, etc. Severe allergic reactions are rare.

Description

Cetrorelix acetate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. Cetrorelix acetate is an analog of native GnRH with substitutions of amino acids at positions 1, 2, 3, 6, and 10. The molecular formula is C70H92CIN17O14 (Ac-D-Nal1-D-Cpa2-D-Pal3-Ser4-Tyr5- D-Cit6-Leu7-Arg8-Pro9-D -Ala10-NH2), and the molecular weight is 1431 Dalton, calculated as the anhydrous free base.

Cetrorelix Preparation Products And Raw materials

Raw materials

Boc-Arg(Tos)-OH BOC-L-Proline BOC-L-Leucine

Preparation Products

Cetrorelix Suppliers

Global Suppliers ( 305)
Supplier Tel Email Country ProdList Advantage
Hangzhou nuotong biotechnology co. LTD 0571-86297909 15268405618 sisi.xiang@sinopep.com China 86 58
Chinapeptide 15295566865 glenn@synpeptide.com China 33 58
Chinese Peptide Company 0571-86737118-8680 15988144796 sales@chinesepeptide.com China 10 58
Kaifeng Mingren Pharmaceutical Co.,LTD 13503833127 zhanghuiyuan@shmathcon.com China 39 58
Hangzhou Xinokai Biomedical Technology Co., Ltd. 18758067196 guxuran@synerchem.cn China 124 58
SU ZHOU MOTIF BIOTECH CO.,LTD 18151592215 18516107567 info@motifbiotech.com China 999 58
Harbin Jixianglong Biotech Co., Ltd. 18246018015 1348764518@qq.com China 22 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Supplier Advantage
Hangzhou nuotong biotechnology co. LTD 58
Chinapeptide 58
Chinese Peptide Company 58
Kaifeng Mingren Pharmaceutical Co.,LTD 58
Hangzhou Xinokai Biomedical Technology Co., Ltd. 58
SU ZHOU MOTIF BIOTECH CO.,LTD 58
Harbin Jixianglong Biotech Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chembest Research Laboratories Limited 61

View Latest Price from Cetrorelix manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cetrorelix acetate pictures 2026-09-17 Cetrorelix acetate
120287-85-6
 1g 98%min 1000g WUHAN FORTUNA CHEMICAL CO., LTD
Cetrorelix pictures 2026-09-14 Cetrorelix
120287-85-6
 1g >=99% (HPLC) USP43 10000000 Chengdu Shengnuo Biopharm Co.,Ltd
Cetrorelix pictures 2026-06-30 Cetrorelix
120287-85-6
 1kg 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
  • Cetrorelix pictures
  • Cetrorelix
    120287-85-6
  • >=99% (HPLC) USP43
  • Chengdu Shengnuo Biopharm Co.,Ltd
  • Cetrorelix pictures
  • Cetrorelix
    120287-85-6
  • $0.00
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd

Cetrorelix Spectrum

Cetrorelix acetate(120287-85-6)MS

120287-85-6 (Cetrorelix) Related Search:

CETRORELIX TRIFLUOROACETATE Butyl acetate Octreotide acetate Sodium acetate Methyl acetate
Vinyl acetate Ethyl acetate Tocopheryl acetate Glatiramer acetate Potassium Acetate
Triptorelin CETRORELIX CETRORELIX Argipressine acetate Abarelix
GHRP-2 Goserelin acetate DESMOPRESSIN

1of4

AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH CETRORELIX CETRORELIX ACID CETRIZINEDIHYDROCHLORIDE N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2 Cetrorelixum [inn-latin] Unii-oon1hfz4ba D-AlaninaMide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aMinocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl- Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2 CETRORELIX Cetrorelixum 120287-85-6 20287-85-6 C70H92ClN17O14 C70H92CIN17O14C2H4O2 Peptide GYL