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adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-

CAS No.
1048021-78-8
Chemical Name:
adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-
Synonyms
3’-N3-dATP;3'-azidomethyl-dATP;3′-O-Azidomethyl-dATP 100mM Sodium Solution;3'-azidomethyl-2'-Deoxyadenosine-5'-Triphosphate;3'-O-Azidomethyl-2'-deoxyadenosine 5'-triphosphate;adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-;[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-(azidomethoxy)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
CBNumber:
CB110762199
Molecular Formula:
C11H17N8O12P3
Molecular Weight:
546.22
MDL Number:
MOL File:
1048021-78-8.mol
TDS File:
TDS
Last updated:2026-07-30 08:05:20

adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- Properties

pka 0.796±0.50(predicted)

adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- Chemical Properties, Uses, Production

Uses

3′-O-N3-dATP (3′-O-Azidomethyl dATP) is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm-1, which determines the DNA sequences continuously[1].

References

[1] Palla M, et al., DNA sequencing by synthesis using 3'-O-azidomethyl nucleotide reversible terminators and surface-enhanced Raman spectroscopic detection. RSC Adv. 2014 Jan 1;4(90):49342-49346. DOI:10.1039/C4RA08398A

adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- Preparation Products And Raw materials

Raw materials

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adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- 3′-O-Azidomethyl-dATP 100mM Sodium Solution 3'-azidomethyl-2'-Deoxyadenosine-5'-Triphosphate 3'-azidomethyl-dATP 3’-N3-dATP [[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-(azidomethoxy)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate 3'-O-Azidomethyl-2'-deoxyadenosine 5'-triphosphate 1048021-78-8