ChemicalBook >> CAS DataBase List >>Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl-

Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl-

Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- structure

CAS No.: 2734168-51-3

Chemical Name:: Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl-

Synonyms: HPK1-IN-12;Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl-

CBNumber:: CB110842516

Molecular Formula:: C25H24FN5O2

Molecular Weight:: 445.49

MDL Number:

MOL File:: 2734168-51-3.mol

MSDS File:: SDS

Last updated:2026-04-21 10:31:43

Request For Quotation

Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- Properties

Boiling point	642.2±55.0 °C(Predicted)
Density	1.42±0.1 g/cm3(Predicted)
pka	9.74±0.40(Predicted)

Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- Chemical Properties, Uses, Production

Uses

HPK1-IN-12 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-12 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 85) [1].

References

[1] Xie, Yuli, et al. Hpk1 inhibitor and preparation method and use thereof. Patent WO2021213317A1.

Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29873	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58

Supplier	Advantage
BOC Sciences	65
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Latest Price from Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-20	HPK1-IN-12 2734168-51-3	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

HPK1-IN-12
2734168-51-3
$1520.00-2500.00
TargetMol Chemicals Inc.

2734168-51-3 (Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl-) Related Search:

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Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- HPK1-IN-12 2734168-51-3