Chimaphilin
- CAS No.
- 482-70-2
- Chemical Name:
- Chimaphilin
- Synonyms
- 7-Dimethyl-1;2,7-dimethylnaphthalene-1,4-dione;2,7-Dimethyl-1,4-naphthalenedione;1,4-Naphthalenedione, 2,7-dimethyl-
- CBNumber:
- CB11178255
- Molecular Formula:
- C12H10O2
- Molecular Weight:
- 186.21
- MDL Number:
- MOL File:
- 482-70-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Chimaphilin 99.80% | CS-0034366 | 1mg | $482 |
| Chimaphilin 99.80% | CS-0034366 | 5mg | $1446 |
| Chimaphilin 99.80% | CS-0034366 | 10mg | $2459 |
| Chimaphilin 98% | AA00DGVF | 1mg | $152 |
| Chimaphilin 98% | AA00DGVF | 5mg | $326 |
| Melting point | 113.5-114.5°; mp 232-233° |
|---|---|
| Boiling point | 346.8±42.0 °C(Predicted) |
| Density | 1.187 |
| FDA UNII | U8Z086618U |
Chimaphilin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0034366 | Chimaphilin 99.80% | 482-70-2 | 1mg | $482 | 2026-06-04 | Buy |
| ChemScene | CS-0034366 | Chimaphilin 99.80% | 482-70-2 | 5mg | $1446 | 2026-06-04 | Buy |
| ChemScene | CS-0034366 | Chimaphilin 99.80% | 482-70-2 | 10mg | $2459 | 2026-06-04 | Buy |
| aablocks | AA00DGVF | Chimaphilin 98% | 482-70-2 | 1mg | $152 | 2026-05-28 | Buy |
| aablocks | AA00DGVF | Chimaphilin 98% | 482-70-2 | 5mg | $326 | 2026-05-28 | Buy |
Chimaphilin Chemical Properties,Uses,Production
Uses
Chimaphilin is an IGF-1R inhibitor (IC50: 0.086 μM). Chimaphilin has antifungal, antioxidant and anticancer activities. Chimaphilin inhibits the growth of both drug-sensitive and drug-resistant osteosarcoma cell lines. Chimaphilin can induce cancer cell apoptosis. Chimaphilin is a main component of pyrola[1][2].
Definition
ChEBI: Chimaphylin is a member of 1,4-naphthoquinones.
References
[1] Daqian W, et al. Chimaphilin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines through insulin-like growth factor-I receptor (IGF-IR) signaling. Chem Biol Interact. 2015 Jul 25;237:25-30. DOI:10.1016/j.cbi.2015.05.008
[2] Ma WD, et al. Chimaphilin induces apoptosis in human breast cancer MCF-7 cells through a ROS-mediated mitochondrial pathway. Food Chem Toxicol. 2014 Aug;70:1-8. DOI:10.1016/j.fct.2014.04.014
Chimaphilin Preparation Products And Raw materials
Raw materials
Preparation Products
Chimaphilin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
| Beijing OKA biological technology co., LTD | 010-62971590 18548936886 | 3462612863@qq.com | China | 10063 | 58 |
