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1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)-

1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)- structure

CAS No.: 2669070-40-8

Chemical Name:: 1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)-

Synonyms: BuChE-IN-1;1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)-

CBNumber:: CB112223775

Molecular Formula:: C23H23FN2O4S

Molecular Weight:: 442.5

MDL Number:

MOL File:: 2669070-40-8.mol

MSDS File:: SDS

Last updated:2026-04-21 10:31:43

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1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)- Properties

Boiling point	625.7±55.0 °C(Predicted)
Density	1.308±0.06 g/cm3(Predicted)
pka	2.19±0.10(Predicted)

1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)- Chemical Properties, Uses, Production

Uses

BuChE-IN-1 (Compound 23) is a potent inhibitor of butyrylcholinesterase (BuChE). Butyrylcholinesterase (BuChE) is recently regarded as a biomarker in progressed Alzheimer’s disease (AD). BuChE-IN-1 shows low cytotoxicity and high blood brain barrier (BBB) permeability. BuChE-IN-1 is a promising BuChE inhibitor for the research of AD[1].

References

[1] MeiyangXi, et al. Design, synthesis, biological evaluation and molecular modeling of N-isobutyl-N-((2-(p-tolyloxymethyl)thiazol-4yl)methyl)benzo[d][1,3] dioxole-5-carboxamides as selective butyrylcholinesterase inhibitors.

1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)- Suppliers

Global Suppliers ( 2)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Latest Price from 1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-20	BuChE-IN-1 2669070-40-8	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

BuChE-IN-1
2669070-40-8
$1520.00-2500.00
TargetMol Chemicals Inc.

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1,3-Benzodioxole-5-carboxamide, N-[[2-[(4-fluorophenoxy)methyl]-4-thiazolyl]methyl]-N-(2-methylpropyl)- BuChE-IN-1 2669070-40-8