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cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal)

CAS No.
2619854-01-0
Chemical Name:
cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal)
Synonyms
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal];cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal)
CBNumber:
CB112305772
Molecular Formula:
C63H81N19O7
Molecular Weight:
1216.44
MDL Number:
MOL File:
2619854-01-0.mol
Last updated:2025-06-18 16:39:27

cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal) Properties

Density 1.43±0.1 g/cm3(Predicted)
pka 12.87±0.70(Predicted)
Sequence c[Arg-Arg-Arg-Arg-{D-2-Nal}-{D-2-Nal}-{D-2-Nal}]

cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal) Chemical Properties, Uses, Production

Uses

c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively[1].

References

[1] Sandeep Lohan, et al. Small Amphiphilic Peptides: Activity Against a Broad Range of Drug-Resistant Bacteria and Structural Insight into Membranolytic Properties. J Med Chem. 2022 Jan 13;65(1):665-687. DOI:10.1021/acs.jmedchem.1c01782

cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal) Preparation Products And Raw materials

Raw materials

Preparation Products

cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal) Suppliers

Global Suppliers ( 12)
Supplier Tel Email Country ProdList Advantage
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
Hangzhou Go Top Peptide Biotech 0571-88211921 17357109671 sales3@gotopbio.com China 2988 58
Shaoxing Junyu Biotechnology Co., LTD 0571-0571-88211921 19105816207 sales4@gotopbio.com China 5135 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 0571-87213919 17306812703 3007955328@qq.com China 7446 58
Shanghai HongTide Biotechnology Co.,Ltd. 15318089928 alex@hanhonggroup.com China 4604 58
Combio (Suzhou) Ltd. 17751201929; 17751201929 jianyang_yu@combiosz.com China 2989 58
Zhejiang Jiekun Biotechnology Co., Ltd 0571-88211921 15397062932 sales1@gotopbio.com China 4864 58
Taiyuan Bailihengkang Biotechnology Co., Ltd 19135651983 18611134419@163.com China 4416 58
Nanjing Typeptide Biotechnology Co.,Ltd. 19961912513; 19941518170 sales@typeptide.com China 4452 58
YantaiBio 13758194781; 13758194781 764619768@qq.com China 1755 58
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] cyclo(Arg-Arg-Arg-Arg-Nal-Nal-Nal) 2619854-01-0 C63H81N19O7