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ChemicalBook >> CAS DataBase List >>Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]-

Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]-

Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- Structure
Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- structure
CAS No.
2348795-14-0
Chemical Name:
Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]-
Synonyms
N-Cyclopentyl-3-(3-(4-methoxyphenyl)acrylamido)benzamide;Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]-
CBNumber:
CB112652197
Molecular Formula:
C22H24N2O3
Molecular Weight:
364.44
MDL Number:
MOL File:
2348795-14-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:28
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Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- Properties

Boiling point 636.1±55.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
pka 13.47±0.70(Predicted)
form Solid
color Off-white to light yellow

Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0611702 TGFβ1-IN-1 99.47% 2348795-14-0 5mg $152 2026-06-04 Buy
ChemScene CS-0611702 TGFβ1-IN-1 99.47% 2348795-14-0 10mg $249 2026-06-04 Buy
ChemScene CS-0611702 TGFβ1-IN-1 99.47% 2348795-14-0 25mg $498 2026-06-04 Buy
ChemScene CS-0611702 TGFβ1-IN-1 99.47% 2348795-14-0 50mg $812 2026-06-04 Buy
ChemScene CS-0611702 TGFβ1-IN-1 99.47% 2348795-14-0 100mg $1300 2026-06-04 Buy
Product number Packaging Price Buy
CS-0611702 5mg $152 Buy
CS-0611702 10mg $249 Buy
CS-0611702 25mg $498 Buy
CS-0611702 50mg $812 Buy
CS-0611702 100mg $1300 Buy

Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- Chemical Properties, Uses, Production

Uses

TGFβ1-IN-1 (compound 42) is a potent, orally active TGF-β1 inhibitor. TGFβ1-IN-1 inhibits the upregulation of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in liver fibrosis disease studies[1].

in vivo

TGFβ1-IN-1 (compound 42) (p.o., 15 or 30 mg/kg, daily, 3weeks) prevents CCl4-induced liver injury and fibrosis, inhibits the activation of hepatic stellate cell (HSC) and epithelial-mesenchymal transition (EMT), and improves the immune microenvironment of CCl4-induced liver fibrosis as well as CCl4-induced systemic toxicity in C57BL/6J mice[1].

Animal Model:Liver fibrosis C57BL/6J mice induced by CCl4[1]
Dosage:15 or 30 mg/kg
Administration:Oral administration; daily; 3 weeks
Result:Significantly prevented CCl4-induced liver injury and reduced liver weight factor, serum ALT, AST, CHO and TG levels.
Significantly improved structural damage and inflammatory cell infiltration in the liver, and reduced collagen deposition in liver tissue.
Reduced accumulation of CCl4-induced immune cells, such as hepatic macrophages (F4/80+ CD11b+), Th1 cells (CD69+ CD4+), and Th2 cells (CD69+ CD8+) so on.

References

[1] Lin Yue, et al. Discovery and evaluation of phenacrylanilide derivatives as novel potential anti-liver fibrosis agents. Eur J Med Chem. 2022 Nov 15;242:114685. DOI:10.1016/j.ejmech.2022.114685

Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9787 55
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4999 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Aikon International Limited 17714375163 hywu@aikonchem.com China 9974 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai Fengyong Biotechnology Co., Ltd. 021-10000000 13000000000 gzj@abmole.cn China 9323 58
Supplier Advantage
Tianjin Kailiqi Biotechnology Co., Ltd. 55
TargetMol Chemicals Inc. 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58
Aikon International Limited 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Fengyong Biotechnology Co., Ltd. 58

View Latest Price from Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TGFβ1-IN-1 pictures 2025-12-22 TGFβ1-IN-1
2348795-14-0
 $92.00 99.89% 10g TargetMol Chemicals Inc.
  • TGFβ1-IN-1 pictures
  • TGFβ1-IN-1
    2348795-14-0
  • $92.00
  • 99.89%
  • TargetMol Chemicals Inc.

2348795-14-0 (Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]-) Related Search:

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TGFBR2/TGF-beta RII protein, Human (Biotinylated, HEK293, Fc-Avi)

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Benzamide, N-cyclopentyl-3-[[3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]- N-Cyclopentyl-3-(3-(4-methoxyphenyl)acrylamido)benzamide 2348795-14-0