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ChemicalBook >> CAS DataBase List >>1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Structure
1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- structure
CAS No.
2485758-50-5
Chemical Name:
1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-
Synonyms
JAK2/STAT3-IN-1;1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-
CBNumber:
CB112756402
Molecular Formula:
C34H35BrF3N5O2
Molecular Weight:
682.57
MDL Number:
MOL File:
2485758-50-5.mol
MSDS File:
SDS
Last updated:2026-08-20 20:20:01
Request For Quotation

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Properties

Boiling point 776.2±70.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
pka 15+-.0.60(Predicted)

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0130244 JAK2/STAT3-IN-1 2485758-50-5 1mg $590 2026-06-04 Buy
ChemScene CS-0130244 JAK2/STAT3-IN-1 2485758-50-5 5mg $1466 2026-06-04 Buy
ChemScene CS-0130244 JAK2/STAT3-IN-1 2485758-50-5 10mg $2124 2026-06-04 Buy
ACHEMBLOCK AD265378 JAK2/STAT3-IN-1 98% 2485758-50-5 1MG $350 2026-05-27 Buy
ACHEMBLOCK AD265378 JAK2/STAT3-IN-1 98% 2485758-50-5 5MG $865 2026-05-27 Buy
Product number Packaging Price Buy
CS-0130244 1mg $590 Buy
CS-0130244 5mg $1466 Buy
CS-0130244 10mg $2124 Buy
AD265378 1MG $350 Buy
AD265378 5MG $865 Buy

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Chemical Properties, Uses, Production

Uses

JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 μM. JAK2/STAT3-IN-1 shows anti-tumor activity[1].

References

[1] Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375. DOI:10.1016/j.ejmech.2020.112375

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Supplier Advantage
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Amole Biotechnology Co., Ltd. 58

View Latest Price from 1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
JAK2/STAT3-IN-1 pictures 2026-08-19 JAK2/STAT3-IN-1
2485758-50-5
 $293.00-987.00 97.35% 10g TargetMol Chemicals Inc.

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Spectrum

1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-(2485758-50-5)1HNMR

2485758-50-5 (1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-) Related Search:

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1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- JAK2/STAT3-IN-1 2485758-50-5 C34H35BrF3N5O2