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3,5-Diaminopyridine

3,5-Diaminopyridine Structure
3,5-Diaminopyridine structure
CAS No.
4318-78-9
Chemical Name:
3,5-Diaminopyridine
Synonyms
Pyridine-3,5-diamine;3,5-Diaminopyridine;3,5-diamino-pyridin;3,5-PYRIDINEDIAMINE;3,5-Diamine pyridine;(5-amino-3-pyridyl)amine;3,5-Diaminopyridine ,97%;3,5-Diaminopyridine dihydrochloride;3,5-DIAMINOPYRIDINE ISO 9001：2015 REACH
CBNumber:
CB1127940
Molecular Formula:
C5H7N3
Molecular Weight:
109.13
MDL Number:
MFCD00955693
MOL File:
4318-78-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:36
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3,5-Diaminopyridine Properties

Melting point 112-113℃
Boiling point 378℃
Density 1.251
Flash point 211℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 7.10±0.20(Predicted)
Appearance Brown to black Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

3,5-Diaminopyridine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS39678 Pyridine-3,5-diamine 95% 4318-78-9 1g $88 2026-06-04 Buy
Activate Scientific AS39678 Pyridine-3,5-diamine 95% 4318-78-9 5g $195 2026-06-04 Buy
Matrix Scientific 120056 Pyridine-3,5-diamine 4318-78-9 250.00mg $252 2026-05-18 Buy
Matrix Scientific 120056 Pyridine-3,5-diamine 4318-78-9 1.00g $630 2026-05-18 Buy
Synthonix P41138 Pyridine-3,5-diamine 95% 4318-78-9 100mg $18 2026-05-06 Buy
Product number Packaging Price Buy
AS39678 1g $88 Buy
AS39678 5g $195 Buy
120056 250.00mg $252 Buy
120056 1.00g $630 Buy
P41138 100mg $18 Buy

3,5-Diaminopyridine Chemical Properties, Uses, Production

Uses

3,5-Diaminopyridine is an active ingredient for hair dyes.

Synthesis

Pyridine-3,5-dicarboxamide

4663-99-4

3,5-DIAMINOPYRIDINE

4318-78-9

The general procedure for the synthesis of pyridine-3,5-diamine from pyridine-3,5-dicarboxamide by a modified Hofmann rearrangement reaction is as follows:[39] Pyridine-3,5-dicarboxamide (3.54 g, 21.4 mmol) was dissolved in 4 M NaOH aqueous solution (18 mL). A solution of bromine (2.65 mL, 8.27 g, 51.9 mmol Br2) in 4M aqueous NaOH solution (53 mL) was added slowly and dropwise over 15 min at 0 °C. The reaction mixture was stirred at room temperature for 1 hour until a clarified yellow solution was formed, followed by heating at 75 °C for 6 hours. Upon completion of the reaction, the dark brown solution was washed with ether (50 mL) to remove by-products and then extracted with ethyl acetate (150 mL) for 3 consecutive days. Finally, concentration by vacuum evaporation afforded pyridine-3,5-diamine (1.43 g, 13.0 mmol, 61% yield) as a greenish brown solid (Rf = 0.14, unfolding agent CH2Cl2/MeOH 10:1).

References

[1] Synthesis (Germany), 2014, vol. 46, # 9, p. 1243 - 1253

3,5-Diaminopyridine Preparation Products And Raw materials

Raw materials

Ethanol Phosphorus oxitrichloride Palladium Phosphorus pentachloride Hydrogen
Nitric acid Sodium hydroxide 2-Hydroxy-5-nitropyridine 2-Chloro-3,5-dinitropyridine Pyridine-3,5-dicarboxamide

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Preparation Products

3,5-Diaminopyridine Suppliers

Global Suppliers ( 117)
Supplier Tel Email Country ProdList Advantage
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1995 58
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Jinan Trio PharmaTech Co., Ltd. 0531-88811783 sales@trio-pharmatech.com China 1856 62
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
RuiErKang Pharmaceuticals, Inc. 2921645477 2921645477@qq.com China 132 58
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9510 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9336 55
SynAsst Chemical. 021-60343070 China 12731 55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. +86-28-85122536 85324413 market@astatech.cn China 8016 55
Supplier Advantage
Chengdu Forest Science and Technology Development Co., Ltd. 58
Capot Chemical Co., Ltd 66
Pure Chemistry Scientific Inc. 62
Jinan Trio PharmaTech Co., Ltd. 62
Spectrum Chemical Manufacturing Corp. 60
RuiErKang Pharmaceuticals, Inc. 58
Shanghai Topbiochem Technology Co., Ltd 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
SynAsst Chemical. 55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. 55

View Latest Price from 3,5-Diaminopyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-DIAMINOPYRIDINE pictures 2025-06-25 3,5-DIAMINOPYRIDINE
4318-78-9
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
3,5-DIAMINOPYRIDINE pictures 2019-12-31 3,5-DIAMINOPYRIDINE
4318-78-9
 $1.00 1KG 99% 10000KGS Career Henan Chemical Co

3,5-Diaminopyridine Spectrum

3,5-DIAMINOPYRIDINE(4318-78-9)1HNMR

4318-78-9 (3,5-Diaminopyridine) Related Search:

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Pyridine-2,4-dicarbonitrile Pyridine-2,4-diamine 5-BROMO-2,3-DIAMINOPYRIDINE 97%,5-BROMO-2,3-DIAMINOPYRIDINE Phenazopyridine hydrochloride 3,4-Pyridinediamine,5-methyl-(9CI)
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3,5-PYRIDINEDIAMINE 3,5-diamino-pyridin 3,5-Diaminopyridine ,97% (5-amino-3-pyridyl)amine 3,5-DIAMINOPYRIDINE ISO 9001：2015 REACH 3,5-Diaminopyridine dihydrochloride 3,5-Diamine pyridine Pyridine-3,5-diamine 3,5-Diaminopyridine 4318-78-9 Pyridine Pyridines