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Z-VAL-DL-ASP-FLUOROMETHYLKETONE

CAS No.
582316-00-5
Chemical Name:
Z-VAL-DL-ASP-FLUOROMETHYLKETONE
Synonyms
Z-VD-FMK;Z-Val-DL-Asp-FMK;Z-Val-Asp-Fluoromethyl Ketone;Z-VAL-DL-ASP-FLUOROMETHYLKETONE;Z-VAL-ASP-FLUOROMETHYL KETONE;Z-VD-FMK;3-({N-[(Benzyloxy)Carbonyl]-L-Valyl}Amino)-5-Fluoro-4-Oxopentanoic Acid;3-((S)-2-(((Benzyloxy)carbonyl)aMino)-3-MethylbutanaMido)-5-fluoro-4-oxopentanoic acid;Pentanoic acid,5-fluoro-3-[[(2S)-3-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]butyl]amino]-4-oxo-
CBNumber:
CB1128033
Molecular Formula:
C18H23FN2O6
Molecular Weight:
382.38
MDL Number:
MFCD08457673
MOL File:
582316-00-5.mol
MSDS File:
SDS
Last updated:2025-08-21 22:16:43
Product description Number Pack Size Price
MX1013 27904 5mg $68
MX1013 27904 10mg $121
MX1013 27904 25mg $268
Z-Val-Asp-FluoromethylKetone 96% BP-22470 100mg $540
Z-VAL-DL-ASP-FLUOROMETHYLKETONE 95.00% API0004663 1MG $554

Z-VAL-DL-ASP-FLUOROMETHYLKETONE Properties

Boiling point 639.8±55.0 °C(Predicted)
Density 1.258±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml; Ethanol: 10 mg/ml
form A solid
pka 3.92±0.19(Predicted)
color White to off-white

Z-VAL-DL-ASP-FLUOROMETHYLKETONE price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27904 MX1013 582316-00-5 5mg $68 2024-03-01 Buy
Cayman Chemical 27904 MX1013 582316-00-5 10mg $121 2024-03-01 Buy
Cayman Chemical 27904 MX1013 582316-00-5 25mg $268 2024-03-01 Buy
BroadPharm BP-22470 Z-Val-Asp-FluoromethylKetone 96% 582316-00-5 100mg $540 2021-12-16 Buy
American Custom Chemicals Corporation API0004663 Z-VAL-DL-ASP-FLUOROMETHYLKETONE 95.00% 582316-00-5 1MG $554 2021-12-16 Buy
Product number Packaging Price Buy
27904 5mg $68 Buy
27904 10mg $121 Buy
27904 25mg $268 Buy
BP-22470 100mg $540 Buy
API0004663 1MG $554 Buy

Z-VAL-DL-ASP-FLUOROMETHYLKETONE Chemical Properties,Uses,Production

Uses

MX1013 is a potent, irreversible dipeptide caspase inhibitor vith?antiapoptotic activity. MX1013 inhibits recombinant human caspase 3 with an IC50?of 30 nM[1].

in vivo

MX1013 is an effective antiapoptotic agent?in vivo. MX1013 not only inhibits local tissue apoptosis, but also can protect animals against its lethal effects[1].

Animal Model:Female ND4 Swiss Webster mice (16.5-21 g)[1]
Dosage:0, 0.25, 1, 10 mg/kg (formulated in an aqueous vehicle containing 50 mm?Tris-HCl, pH 8.0)
Administration:Injected i.v.
Result:The lowest dose of 0.25 mg/kg protected 66% of the mice from the lethal effects of anti-Fas antibody at the 3 h time point, and 1 and 10 mg/kg?dose protected 100% of the mice at the 3 h time point.

IC 50

Caspase

References

[1] Wu Yang,?et al. MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity. Br J Pharmacol.?2003 Sep;140(2):402-12. DOI:10.1038/sj.bjp.0705450

Z-VAL-DL-ASP-FLUOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

Z-VAL-DL-ASP-FLUOROMETHYLKETONE Suppliers

Global( 31)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 sales@sarms4muscle.com China 10473 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39032 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9793 50
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58

View Lastest Price from Z-VAL-DL-ASP-FLUOROMETHYLKETONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MX1013 pictures 2025-08-21 MX1013
582316-00-5
US $30.00 / mg 10g TargetMol Chemicals Inc.
  • MX1013 pictures
  • MX1013
    582316-00-5
  • US $30.00 / mg
  • TargetMol Chemicals Inc.

582316-00-5(Z-VAL-DL-ASP-FLUOROMETHYLKETONE)Related Search:

Z-VAL-DL-ASP-FLUOROMETHYLKETONE Z-VD-FMK Pentanoic acid,5-fluoro-3-[[(2S)-3-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]butyl]amino]-4-oxo- 3-((S)-2-(((Benzyloxy)carbonyl)aMino)-3-MethylbutanaMido)-5-fluoro-4-oxopentanoic acid Z-Val-Asp-Fluoromethyl Ketone Z-VAL-ASP-FLUOROMETHYL KETONE;Z-VD-FMK 3-({N-[(Benzyloxy)Carbonyl]-L-Valyl}Amino)-5-Fluoro-4-Oxopentanoic Acid Z-Val-DL-Asp-FMK 582316-00-5 C18H23FN2O6 An irreversible general caspase inhibitor.