ChemicalBook >> CAS DataBase List >>1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)

CAS No.
366453-22-7
Chemical Name:
1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)
Synonyms
4-methoxyisoindoleline-1-one;4-Methoxy-2,3-dihydro-isoindol-1-one;2,3-Dihydro-4-methoxy-1H-isoindol-1-one;4-Methoxy-2,3-dihydro-1H-isoindol-1-one;1H-Isoindol-1-one, 2,3-dihydro-4-Methoxy-;1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)
CBNumber:
CB11301637
Molecular Formula:
C9H9NO2
Molecular Weight:
163.17
MDL Number:
MFCD09701287
MOL File:
366453-22-7.mol
MSDS File:
SDS
Last updated:2026-05-27 23:06:44

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) Properties

Melting point >200 °C
Boiling point 439.2±45.0 °C(Predicted)
Density 1.208±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 14.37±0.20(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HS Code  2925199590

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR305267 4-Methoxy-2,3-dihydro-1H-isoindol-1-one >96% 366453-22-7 250mg $21 2026-06-04 Buy
Apolloscientific OR305267 4-Methoxy-2,3-dihydro-1H-isoindol-1-one >96% 366453-22-7 1g $39 2026-06-04 Buy
Apolloscientific OR305267 4-Methoxy-2,3-dihydro-1H-isoindol-1-one >96% 366453-22-7 5g $179 2026-06-04 Buy
Apolloscientific OR305267 4-Methoxy-2,3-dihydro-1H-isoindol-1-one >96% 366453-22-7 25g $816 2026-06-04 Buy
Apolloscientific OR305267 4-Methoxy-2,3-dihydro-1H-isoindol-1-one >96% 366453-22-7 100g $2633 2026-06-04 Buy
Product number Packaging Price Buy
OR305267 250mg $21 Buy
OR305267 1g $39 Buy
OR305267 5g $179 Buy
OR305267 25g $816 Buy
OR305267 100g $2633 Buy

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) Chemical Properties,Uses,Production

Synthesis

Methyl 2-bromomethyl-3-methoxybenzoate

71887-28-0

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)

366453-22-7

Step b: A mixed solution of methyl 2-bromomethyl-3-methoxybenzoate (997 mg, 3.85 mmol) and ammonium hydroxide (9 mL) in THF (19 mL) was reacted with stirring at room temperature for 4 hours. After completion of the reaction, the reaction mixture was concentrated to dryness under reduced pressure. The resulting residue was purified by fast column chromatography (eluent: hexane/ethyl acetate, 40/60 with 1% methanol) to afford 4-methoxyisoindolin-1-one as a white solid (595 mg, 95% yield).

References

[1] Chinese Chemical Letters, 2012, vol. 23, # 1, p. 9 - 12
[2] Patent: WO2004/26875, 2004, A1. Location in patent: Page 38
[3] Patent: US2004/106791, 2004, A1. Location in patent: Page 9
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 2, p. 814 - 819

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 85)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7882 64
QINGDAO CARELONGPHARMATECH CO.,LTD 053288191853 13061484198 sales@carelongchem.com China 455 57
Sphinx Scientific Laboratory (Tianjin) Co., Ltd. 022-66211289-843 13672102692 contact@sphinxpharm.com China 361 62
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9513 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
SynAsst Chemical. 021-60343070 China 12731 55

View Lastest Price from 1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methoxyisoindolin-1-one pictures 2026-02-02 4-Methoxyisoindolin-1-one
366453-22-7
5mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) pictures 2020-01-13 1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI)
366453-22-7
$5.50 1KG 98%min 1kg-100kg Career Henan Chemical Co

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) Spectrum

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9CI) 1H-Isoindol-1-one, 2,3-dihydro-4-Methoxy- 4-Methoxy-2,3-dihydro-1H-isoindol-1-one 4-Methoxy-2,3-dihydro-isoindol-1-one 2,3-Dihydro-4-methoxy-1H-isoindol-1-one 4-methoxyisoindoleline-1-one 366453-22-7 METHOXY