palitantin
- CAS No.
- 15265-28-8
- Chemical Name:
- palitantin
- Synonyms
- palitantin;(-)-Palitantine;(2R)-2β-(Hydroxymethyl)-3α-[(1E,3E)-1,3-heptadienyl]-5β,6β-dihydroxycyclohexanone;(2R,3S,5R,6R)-rel-3-(1E,3E)-1,3-Heptadienyl-5,6-dihydroxy-2-(hydroxymethyl)-cyclohexanone;Cyclohexanone, 3-(1E,3E)-1,3-heptadien-1-yl-5,6-dihydroxy-2-(hydroxymethyl)-, (2R,3S,5R,6R)-rel-
- CBNumber:
- CB11305019
- Molecular Formula:
- C14H22O4
- Molecular Weight:
- 254.32
- MDL Number:
- MOL File:
- 15265-28-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 169℃ (ethyl acetate ) |
|---|---|
| alpha | 235461 +4.4° (c = 0.8 in CHCl3) |
| Boiling point | 429.064±45.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.205±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 12.219±0.70(predicted) |
| form | White solid. |
| color | White |
| FDA UNII | 25M588OEZF |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| NFPA 704 |
|
palitantin price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25208 | Palitantin ≥95% | 15265-28-8 | 500μg | $112 | 2026-04-30 | Buy |
| Cayman Chemical | 25208 | Palitantin ≥95% | 15265-28-8 | 2.5mg | $390 | 2026-04-30 | Buy |
| Usbiological | 207318 | Palitantin (NSC 246119) ~95%(HPLC) | 15265-28-8 | 1mg | $379 | 2026-06-03 | Buy |
| Adipogen Life Sciences | AG-CN2-0140-M001 | Palitantin ≥95%(HPLC) | 15265-28-8 | 1mg | $155 | 2026-05-06 | Buy |
| aablocks | AA00AKM4 | Palitantin >95% | 15265-28-8 | 1mg | $362 | 2026-05-28 | Buy |
palitantin Chemical Properties, Uses, Production
Description
Palitantin is a fungal metabolite originally isolated from P. palitans. It inhibits HIV-1 integrase with IC50 values of 350 and 268 μM for 3’-processing and strand transfer activity, respectively. Palitantin has been used as a standard for dereplication of natural products.
Uses
Palitantin is an antifungal and antiprotozoal compound.
IC 50
Leishmania; Fungal Metabolite
storage
+4°C
References
[1] J H BIRKINSHAW H R. Studies in the biochemistry of micro-organisms: Palitantin, C(14)H(22)O(4), a hitherto undescribed metabolic product of Penicillium palitans Westling.[J]. Biochemical Journal, 1936, 30 5: 801-808. DOI: 10.1042/bj0300801
[2] HUIXIAO HONG. Discovery of HIV-1 Integrase Inhibitors by Pharmacophore Searching[J]. Journal of Medicinal Chemistry, 1997, 40 6: 930-936. DOI: 10.1021/jm960754h
[3] KRISTIAN F. NIELSEN*. Dereplication of Microbial Natural Products by LC-DAD-TOFMS[J]. Journal of Natural Products , 2011, 74 11: 2338-2348. DOI: 10.1021/np200254t
palitantin Preparation Products And Raw materials
Raw materials
Preparation Products
palitantin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8857 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Shanghai Saikerui Biotechnology Co. , Ltd. | 021-58000709 13120558703 | sales@scrbio.com | China | 9876 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Weiyite Biotechnology Co., Ltd | 15317051735 | zhaojing@wytsci.com | China | 10000 | 58 |
