BIIL 284
- CAS No.
- 346735-24-8
- Chemical Name:
- BIIL 284
- Synonyms
- Amelubant;BIIL 284;Amelubant (BIIL284;Carbamic acid, N-[[4-[[3-[[4-[1-(4-hydroxyphenyl)-1-methylethyl]phenoxy]methyl]phenyl]methoxy]phenyl]iminomethyl]-, ethyl ester
- CBNumber:
- CB11321815
- Molecular Formula:
- C33H34N2O5
- Molecular Weight:
- 538.63
- MDL Number:
- MFCD04034629
- MOL File:
- 346735-24-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Density | 1.15±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 9.83±0.46(Predicted) |
| color | White to off-white |
| FDA UNII | E0018IF0K4 |
BIIL 284 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | WNA73524 | Amelubant | 346735-24-8 | 5mg | $1670.55 | 2026-06-05 | Buy |
| Biosynth | WNA73524 | Amelubant | 346735-24-8 | 10mg | $2672.8 | 2026-06-05 | Buy |
| Biosynth | WNA73524 | Amelubant | 346735-24-8 | 25mg | $5011.5 | 2026-06-05 | Buy |
| Biosynth | WNA73524 | Amelubant | 346735-24-8 | 50mg | $8018.5 | 2026-06-05 | Buy |
| ChemScene | CS-0015047 | Amelubant 98.45% | 346735-24-8 | 5mg | $520 | 2026-06-04 | Buy |
BIIL 284 Chemical Properties,Uses,Production
Uses
Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM in vital cells and membranes. Amelubant (BIIL 284) is a proagent of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1].
IC 50
LTB4: 221 nM (Ki, in vital human granulocytes); LTB4: 230 nM (Ki, in cell membranes)
References
[1] Birke FW, et al. In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist. J Pharmacol Exp Ther. 2001 Apr;297(1):458-66. PMID:11259574
BIIL 284 Preparation Products And Raw materials
Raw materials
Preparation Products
BIIL 284 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10233 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q | meishipharma@126.com | China | 20027 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |
| Anhui JYHX CO., LTD. | 055167162561 13295518198 | wangyanan@ahjyhx.com | China | 2044 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50089 | 58 |
