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S 2238

S 2238 structure

CAS No.: 64815-81-2

Chemical Name:: S 2238

Synonyms: H-D-Phe-pip-Arg-pna;S 2238;H-Phe-pip-Arg-pna;H-Phe-pip-Arg-p-nitroanilide;Chromogenic substrate S-2238;Thrombin Substrate S2238 1 mg;H-D-Phenylalanyl-pip-Arg-p-nitroanilide;H-D-Phenylalanyl-L-pipecolyl-arginine-nitroanilide;D-Phenylalanyl-L-2-piperidinecarbonyl-N-(4-nitro phenyl)-L-argininamide

CBNumber:: CB11352967

Molecular Formula:: C27H36N8O5

Molecular Weight:: 552.63

MDL Number:: MFCD07780999

MOL File:: 64815-81-2.mol

Last updated:2026-07-28 08:09:19

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S 2238 Properties

Density	1.405±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility	DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Sonicated)
form	Solid
pka	13.291±0.20(predicted)
color	White to Off-White
Stability	Hygroscopic

S 2238 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biorbyt Ltd	orb3033079	H-D-Phe-Pip-Arg-pNA 0.98	64815-81-2	100mg	$950	2026-05-06	Buy
Biorbyt Ltd	orb3033079	H-D-Phe-Pip-Arg-pNA 0.98	64815-81-2	250mg	$1380	2026-05-06	Buy
Biorbyt Ltd	orb3033079	H-D-Phe-Pip-Arg-pNA 0.98	64815-81-2	1g	$2500	2026-05-06	Buy
DC Chemicals	DC40319	H-D-Phe-Pip-Arg-pNA >98%	64815-81-2	100mg	$750	2026-05-24	Buy
DC Chemicals	DC40319	H-D-Phe-Pip-Arg-pNA >98%	64815-81-2	250mg	$1100	2026-05-24	Buy

Product number	Packaging	Price	Buy
orb3033079	100mg	$950	Buy
orb3033079	250mg	$1380	Buy
orb3033079	1g	$2500	Buy
DC40319	100mg	$750	Buy
DC40319	250mg	$1100	Buy

S 2238 Chemical Properties, Uses, Production

Uses

H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform[1][2].

References

[1] Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647. DOI:10.1093/ajcp/73.5.639
[2] Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353. PMID:6531759

S 2238 Preparation Products And Raw materials

Raw materials

Preparation Products

S 2238 Suppliers

Global Suppliers ( 9)

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.	0755-23251735 13302967066	sales@geneseqtools.com	China	1466	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10378	58
Shanghai Kaisen Biotechnology Co., Ltd	17558870519	sales02@chemsoon.com	China	1939	58
YantaiBio	13758194781; 13758194781	764619768@qq.com	China	1755	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58

Supplier	Advantage
Hangzhou Peptidego Biotech Co.,Ltd.	58
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
Shanghai Kaisen Biotechnology Co., Ltd	58
YantaiBio	58
TargetMol Chemicals Inc.	58

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S 2238 Chromogenic substrate S-2238 D-Phenylalanyl-L-2-piperidinecarbonyl-N-(4-nitro phenyl)-L-argininamide H-D-Phenylalanyl-L-pipecolyl-arginine-nitroanilide H-D-Phenylalanyl-pip-Arg-p-nitroanilide H-Phe-pip-Arg-pna H-Phe-pip-Arg-p-nitroanilide Thrombin Substrate S2238 1 mg H-D-Phe-pip-Arg-pna 64815-81-2