vanoxonin
- CAS No.
- 86933-99-5
- Chemical Name:
- vanoxonin
- Synonyms
- vanoxonin;MG-245-CF2-A;Antibitic MG-245CF2A;Antibiotic MG 245CF2A;(+)-N-(2,3-Dihydroxybenzoyl)-L-Thr-N5-Ac-N5-hydroxy-L-Orn-OH;N-(2,3-dihydroxybenzoyl)-L-threonyl-N5-acetyl-N5-hydroxy-L-ornithine;N5-Acetyl-N2-[N-(2,3-dihydroxybenzoyl)-L-threonyl]-N5-hydroxy-L-ornithine
- CBNumber:
- CB11370969
- Molecular Formula:
- C18H25N3O9
- Molecular Weight:
- 427.41
- MDL Number:
- MFCD01939818
- MOL File:
- 86933-99-5.mol
- MSDS File:
- SDS
vanoxonin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 32931 | Vanoxonin ≥80% | 86933-99-5 | 1mg | $702 | 2026-04-30 | Buy |
| Biosynth | LDA93399 | Vanoxonin | 86933-99-5 | 1mg | $1261.34 | 2026-06-04 | Buy |
| Biosynth | LDA93399 | Vanoxonin | 86933-99-5 | 5mg | $3564.65 | 2026-06-04 | Buy |
| Biosynth | LDA93399 | Vanoxonin | 86933-99-5 | 10mg | $5703.4 | 2026-06-04 | Buy |
| Biosynth | LDA93399 | Vanoxonin | 86933-99-5 | 25mg | $10694 | 2026-06-04 | Buy |
vanoxonin Chemical Properties, Uses, Production
Uses
Vanoxonin is an inhibitor of thymidylate synthase found in Saccharopolyspora hirsuta with an IC50 value of 0.7 μg/mL[1].
Biological Activity
Vanoxonin is a bacterial metabolite that has been found in S. hirsuta.1 It forms a complex with vanadium, and the complex inhibits thymidylate synthetase with an IC50 value of 0.7 μg/ml. The vanoxonin-vanadium complex is cytotoxic to L1210 leukemia cells (MIC = 25 μg/ml) and increases survival in Ehrlich murine spontaneous adenocarcinoma and L1210 mouse tumor models.
References
1.Kanai, F., Sawa, T., Hamada, M., et al.Vanoxonin, a new inhibitor of thymidylate synthetaseJ. Antibiot. (Tokyo)36(6)656-660(1983)
vanoxonin Preparation Products And Raw materials
Raw materials
Preparation Products
vanoxonin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1246 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
