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RapaBlock

RapaBlock Structure
RapaBlock structure
CAS No.
2474076-02-1
Chemical Name:
RapaBlock
Synonyms
RapaBlock;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-[3-(1-oxido-2-pyridinyl)propyl]-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-
CBNumber:
CB114287296
Molecular Formula:
C49H74N2O13
Molecular Weight:
899.12
MDL Number:
MOL File:
2474076-02-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:50
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RapaBlock Properties

Boiling point 987.640±75.00 °C(Press: 760.00 Torr)(predicted)
Density 1.272±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 9.966±0.70(predicted)
form Solid
color White to off-white

RapaBlock price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0864680 RapaBlock 98.0% 2474076-02-1 5mg $639 2026-06-04 Buy
ChemScene CS-0864680 RapaBlock 98.0% 2474076-02-1 10mg $1029 2026-06-04 Buy
ChemScene CS-0864680 RapaBlock 98.0% 2474076-02-1 25mg $2058 2026-06-04 Buy
ChemScene CS-0864680 RapaBlock 98.0% 2474076-02-1 50mg $3358 2026-06-04 Buy
aablocks AA02E6CC RapaBlock >98% 2474076-02-1 5mg $691 2026-06-03 Buy
Product number Packaging Price Buy
CS-0864680 5mg $639 Buy
CS-0864680 10mg $1029 Buy
CS-0864680 25mg $2058 Buy
CS-0864680 50mg $3358 Buy
AA02E6CC 5mg $691 Buy

RapaBlock Chemical Properties, Uses, Production

Uses

RapaBlock is a potent, non-immunosuppressive and brain-impermeable FKBP12 ligand[1].

References

[1] Ziyang Zhang, et al. Brain-restricted mTOR inhibition with binary pharmacology. Nature. 2022 Sep;609(7928):822-828. DOI:10.1038/s41586-022-05213-y

RapaBlock Preparation Products And Raw materials

Raw materials

Preparation Products

2474076-02-1 (RapaBlock) Related Search:

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RapaBlock 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-[3-(1-oxido-2-pyridinyl)propyl]-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)- 2474076-02-1