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Thalidomide-NH-amido-C8-NH2

Thalidomide-NH-amido-C8-NH2 structure

CAS No.: 2983057-93-6

Chemical Name:: Thalidomide-NH-amido-C8-NH2

Synonyms: Thalidomide-NH-amido-C8-NH2;Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

CBNumber:: CB114293589

Molecular Formula:: C23H31N5O5

Molecular Weight:: 457.52

MDL Number:

MOL File:: 2983057-93-6.mol

Last updated:2025-04-18 09:51:37

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Thalidomide-NH-amido-C8-NH2 Properties

Boiling point	779.4±60.0 °C(predicted)
Density	1.309±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	10.73±0.40(predicted)

Thalidomide-NH-amido-C8-NH2 Chemical Properties, Uses, Production

Uses

Thalidomide-NH-amido-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Thalidomide-NH-amido-C8-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

Thalidomide-NH-amido-C8-NH2 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58

Supplier	Advantage
TargetMol	58

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Thalidomide-NH-amido-C8-NH2 Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 2983057-93-6