CDD-1653
- CAS No.
- 3034216-44-6
- Chemical Name:
- CDD-1653
- Synonyms
- CDD-1653;Benzenesulfonamide, 3-[[5-methoxy-4-(3-oxo-4-phenyl-1-piperazinyl)-2-pyrimidinyl]amino]-
- CBNumber:
- CB114587293
- Molecular Formula:
- C21H22N6O4S
- Molecular Weight:
- 454.5
- MDL Number:
- MOL File:
- 3034216-44-6.mol
- MSDS File:
- SDS
CDD-1653 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1102342 | CDD-1653 99.38% | 3034216-44-6 | 5mg | $173 | 2026-06-04 | Buy |
| ChemScene | CS-1102342 | CDD-1653 99.38% | 3034216-44-6 | 10mg | $282 | 2026-06-04 | Buy |
| ChemScene | CS-1102342 | CDD-1653 99.38% | 3034216-44-6 | 25mg | $574 | 2026-06-04 | Buy |
| ChemScene | CS-1102342 | CDD-1653 99.38% | 3034216-44-6 | 50mg | $921 | 2026-06-04 | Buy |
| ChemScene | CS-1102342 | CDD-1653 99.38% | 3034216-44-6 | 100mg | $1462 | 2026-06-04 | Buy |
CDD-1653 Chemical Properties, Uses, Production
Uses
CDD-1653 is a potent and selective BMPR2 inhibitor (IC50=2.8 nM). CDD-1653 reduces the ability of ATP to bind to the kinase domain of BMPR2, thereby affecting the phosphorylation of SMAD1/5/8 transcription factors, which play a key role in the BMP signaling pathway. CDD-1653 can be used to study diseases related to the BMP signaling pathway[1].
References
[1] Modukuri R K, et al. Discovery of highly potent and BMPR2-selective kinase inhibitors using DNA-encoded chemical library screening[J]. Journal of Medicinal Chemistry, 2023, 66(3): 2143-2160. DOI:10.1021/acs.jmedchem.2c01886
CDD-1653 Preparation Products And Raw materials
Raw materials
Preparation Products
CDD-1653 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9787 | 55 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4999 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| Tianjin Kailiqi Biotechnology Co., Ltd. | 55 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
