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Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]-

CAS No.
3036109-10-8
Chemical Name:
Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]-
Synonyms
Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]-
CBNumber:
CB114684776
Molecular Formula:
C28H25N3O2
Molecular Weight:
435.52
MDL Number:
MOL File:
3036109-10-8.mol
MSDS File:
SDS
Last updated:2025-10-29 15:43:00

Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]- Properties

Boiling point 633.0±55.0 °C(predicted)
Density 1.262±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 7.31±0.40(predicted)
form Solid
color Light yellow to yellow

Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1012325 SDU-071 98.75% 3036109-10-8 5mg $208 2026-06-04 Buy
ChemScene CS-1012325 SDU-071 98.75% 3036109-10-8 10mg $312 2026-06-04 Buy
ChemScene CS-1012325 SDU-071 98.75% 3036109-10-8 25mg $538 2026-06-04 Buy
ACHEMBLOCK AD279638 SDU-071 98% 3036109-10-8 5MG $185 2026-05-27 Buy
ACHEMBLOCK AD279638 SDU-071 98% 3036109-10-8 25MG $475 2026-05-27 Buy
Product number Packaging Price Buy
CS-1012325 5mg $208 Buy
CS-1012325 10mg $312 Buy
CS-1012325 25mg $538 Buy
AD279638 5MG $185 Buy
AD279638 25MG $475 Buy

Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]- Chemical Properties, Uses, Production

Uses

SDU-071 is a potent and orally active inhibitor of BRD4-p53 inhibitor. SDU-071 inhibits MDA-MB-231 cells proliferation with an IC50 of 10.5 μM. SDU-071 induces cell cycle arrest and apoptosis[1].

in vivo

SDU-071 (250 mg/kg for i.g; once daily for 21 days) inhibits tumor growth in a MDA-MB-231 orthotopic mouse xenograft mammary tumor model[1].

Animal Model:DA-MB-231 Orthotopic Mouse Xenograft Mammary Tumor Model[1]
Dosage:50 and 250 mg/kg; Once daily for 21 days
Administration:Gavage administration (i.g.)
Result:Significantly inhibited tumor growth with 49.1% inhibition.
Reduced the Protein levels for BRD4, Mucin5AC, c-Myc, CDK4, and CDK6, upregulated the p21 protein.

References

[1] Wang S, et al. Novel BRD4-p53 Inhibitor SDU-071 Suppresses Proliferation and Migration of MDA-MB-231 Triple-Negative Breast Cancer Cells[J]. ACS Pharmacology & Translational Science, 2024.

Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]- Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4860 55
Shanghai Chaolan Chemical Technology Center QQ:65489617 13301690235 Sales@ATKchemical.com China 9699 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Wuhan Shanhai Zhihe Biotechnology Co., Ltd. 17771424646 shoubull@126.com China 892 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 13720134139 086-15871494362 13720134139 orders@jknbiochem.com China 7283 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 ivan@atkchemical.com China 32997 60

Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]- Spectrum

3036109-10-8 (Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]-) Related Search:

Benzo[h]quinoline-2-methanamine, N-(4-methoxyphenyl)-4-[(4-methoxyphenyl)amino]- 3036109-10-8