ChemicalBook >> CAS DataBase List >>3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)-

3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)-

3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)- structure

CAS No.: 2417373-18-1

Chemical Name:: 3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)-

Synonyms: Nav1.8-IN-14;3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)-

CBNumber:: CB114685526

Molecular Formula:: C18H17F5N4O3S

Molecular Weight:: 464.41

MDL Number:

MOL File:: 2417373-18-1.mol

MSDS File:: SDS

Last updated:2025-04-18 09:51:37

Request For Quotation

3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)- Properties

Density	1.56±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	9.94±0.60(predicted)

3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)- Chemical Properties, Uses, Production

Uses

Nav1.8-IN-14 (compound 20) is a potent and selective Nav1.8 inhibitor. Nav1.8-IN-14 can be used in the study of pain-related diseases[1].

References

[1] Breslin MJ, et al. 2-Aminopyridines as Potent and Selective Nav1.8 Inhibitors Exhibiting Efficacy in a Nonhuman Primate Pain Model. ACS Med Chem Lett. 2024 May 24;15(6):917-923. DOI:10.1021/acsmedchemlett.4c00103

3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)- Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2994	55
Guangzhou Younan Technology Co., Ltd	020-82000279 18988941452	YN_research@163.com	China	2984	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Shanghai Beckham Medical Technology Co., Ltd	55
Guangzhou Younan Technology Co., Ltd	58
TargetMol Chemicals Inc.	58

2417373-18-1 (3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)-) Related Search:

Triamterene Carbamazepine VERATRIDINE Primidone 5,5-Diphenylhydantoin

5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5
-dimethoxyphenylamide

1of2

3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)- Nav1.8-IN-14 2417373-18-1