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ChemicalBook >> CAS DataBase List >>3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE

3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE

3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE Structure
3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE structure
CAS No.
18741-24-7
Chemical Name:
3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE
Synonyms
PDE7-IN-4;AKOS BBS-00007268;PDE7 inhibitor S14;PDE7 inhibitor-S14;TIMTEC-BB SBB000936;3-phenyl-2-thioxo-1H-quinazolin-4-one;PDE-7 inhibitor S14,PDE7 inhibitor S14;2-mercapto-3-phenylquinazolin-4(3H)-one;3-Phenyl-2(1H)-thioxoquinazoline-4(3H)-one;1,3-dihydro-3-phenyl-2-thio-quinazolin-4-on
CBNumber:
CB1146893
Molecular Formula:
C14H10N2OS
Molecular Weight:
254.31
MDL Number:
MFCD00023895
MOL File:
18741-24-7.mol
MSDS File:
SDS
Last updated:2026-05-27 23:09:10
Product description Number Pack Size Price
1,2-DIHYDRO-3-PHENYL-2-THIOXO-4(3H)-QUINAZOLINONE AldrichCPR S525154 1 unit $197
1,2-DIHYDRO-3-PHENYL-2-THIOXO-4(3H)-QUINAZOLINONE Aldrich S525154 1g $179
PDE7-IN-4 95+% CS-0064196 250mg $84
PDE7-IN-4 95+% CS-0064196 1g $199
3-Phenyl-2-thioxo-2,3-dihydro-4(1H)-quinazolinone 047602 500.00mg $66
Request For Quotation

3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE Properties

Melting point 313-314°C
Boiling point 414.8±28.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
pka 10.96±0.20(Predicted)
EWG's Food Scores 1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2933998090
Toxicity mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04508,

3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S525154 1,2-DIHYDRO-3-PHENYL-2-THIOXO-4(3H)-QUINAZOLINONE AldrichCPR 18741-24-7 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S525154 1,2-DIHYDRO-3-PHENYL-2-THIOXO-4(3H)-QUINAZOLINONE Aldrich 18741-24-7 1g $179 2024-03-01 Buy
ChemScene CS-0064196 PDE7-IN-4 95+% 18741-24-7 250mg $84 2026-06-04 Buy
ChemScene CS-0064196 PDE7-IN-4 95+% 18741-24-7 1g $199 2026-06-04 Buy
Matrix Scientific 047602 3-Phenyl-2-thioxo-2,3-dihydro-4(1H)-quinazolinone 18741-24-7 500.00mg $66 2026-05-18 Buy
Product number Packaging Price Buy
S525154 1 unit $197 Buy
S525154 1g $179 Buy
CS-0064196 250mg $84 Buy
CS-0064196 1g $199 Buy
047602 500.00mg $66 Buy

3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE Chemical Properties,Uses,Production

Uses

PDE7-IN-4 is a phosphodiesterase 7 (PDE7) inhibitor with activity that increases intracellular cyclic adenosine monophosphate (cAMP) levels. PDE7-IN-4 shows potential inhibitory effects in neurotransmission and anti-inflammatory applications. PDE7-IN-4 exerts its biological activity by acting on the cAMP/cAMP response element binding protein (CREB) pathway. The development of PDE7-IN-4 aims to improve its pharmacokinetic characteristics to more effectively target neurodegenerative diseases and other inflammation-related diseases[1].

References

[1] Improved Controlled Release and Brain Penetration of the Small Molecule S14 Using PLGA Nanoparticles DOI:10.3390/ijms22063206

3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

2-[[2-(Diethylamino)ethyl]thio]-3-phenylquinazolin-4(3H)-one

3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE Suppliers

Global( 46)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 		13564774135 marketing@targetmol.com United States 19950 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2203 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4860 55
Shanghai YuanYe Biotechnology Co., Ltd. 13636370518 shyysw007@163.com China 89667 60
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2968 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Amadis Chemical Company Limited 		58
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Wuhan Chemwish Technology Co., Ltd 56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Rechem science Co., Ltd. 58

View Lastest Price from 3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PDE7 inhibitor S14 pictures 2026-08-08 PDE7 inhibitor S14
18741-24-7
 $1520.00-2500.00 10g TargetMol Chemicals Inc.

18741-24-7(3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE)Related Search:

3-(2-FLUORO-PHENYL)-2-THIOXO-2,3-DIHYDRO-1H-QUINAZOLIN-4-ONE 7-CHLORO-3-PHENYL-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE 3-(4-BROMO-3-METHYLPHENYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE 3-(3-METHOXYPHENYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE 3-(4-BROMOPHENYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE
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3-(4-TRIFLUOROMETHOXYPHENYL)-2-THIOXO-1,3-DIHYDROQUINAZOLIN-4-ONE 3-(3-FLUORO-PHENYL)-2-THIOXO-2,3-DIHYDRO-1H-QUINAZOLIN-4-ONE N-(4-(4-OXO-2-THIOXO-1,3-DIHYDROQUINAZOLIN-3-YL)PHENYL)ETHANAMIDE 3-(3-CHLORO-PHENYL)-2-THIOXO-2,3-DIHYDRO-1H-QUINAZOLIN-4-ONE 3-(2,4-DICHLORO-PHENYL)-2-THIOXO-2,3-DIHYDRO-1H-QUINAZOLIN-4-ONE
3-(2,4-DIFLUOROPHENYL)-2-THIOXO-1,3-DIHYDROQUINAZOLIN-4-ONE 3-(3,4-DICHLORO-PHENYL)-2-THIOXO-2,3-DIHYDRO-1H-QUINAZOLIN-4-ONE 2-THIOXO-3-(3-TRIFLUOROMETHYL-PHENYL)-2,3-DIHYDRO-1H-QUINAZOLIN-4-ONE

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3-phenyl-2-sulfanylidene-1H-quinazolin-4-one 3-phenyl-2-thioxo-1H-quinazolin-4-one 3-Phenyl-2-thioxo-2,3-dihydro-1H-quinazolin-4-one Quinazolin-4-one, 1,3-dihydro-3-phenyl-2-thio- 4(1H)-Quinazolinone,2,3-dihydro-3-phenyl-2-thioxo- TIMTEC-BB SBB000936 1,3-dihydro-3-phenyl-2-thio-quinazolin-4-on 3-PHENYL-2-THIOXO-2,3-DIHYDRO-4(1H)-QUINAZOLINONE 3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE AKOS BBS-00007268 2,3-dihydro-3-phenyl-2-thioxoquinazolin-4(1H)-one 3-Phenyl-1,2,3,4-tetrahydro-2-thioxoquinazolin-4-one 3-Phenyl-2-thioxo-1,2,3,4-tetrahydroquinazolin 1,2,3,4-Tetrahydro-3-phenyl-2-thioxoquinazoline-4-one 2-Thioxo-1,2-dihydro-3-phenylquinazoline-4(3H)-one 3-Phenyl-2(1H)-thioxoquinazoline-4(3H)-one 3-Phenyl-2-thioxo-1,2-dihydroquinazoline-4(3H)-one 4-Oxo-3-phenyl-1,2,3,4-tetrahydro-2-thioxoquinazoline 1,2-DIHYDRO-3-PHENYL-2-THIOXO-4(3H)-QUINAZOLINONE 2-mercapto-3-phenylquinazolin-4(3H)-one 2-Thio-3-phenyl-1,3-dihydroquinazolin-4-one 3-Phenyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one PDE7 inhibitor S14 PDE7 inhibitor-S14 PDE-7 inhibitor S14,PDE7 inhibitor S14 PDE7-IN-4 3-Phenyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one , PDE7 inhibitor S14 18741-24-7 quinazolinone