ChemicalBook >> CAS DataBase List >>3-(4-Chlorophenyl)propan-1-ol

3-(4-Chlorophenyl)propan-1-ol

3-(4-Chlorophenyl)propan-1-ol structure

CAS No.: 6282-88-8

Chemical Name:: 3-(4-Chlorophenyl)propan-1-ol

Synonyms: Pitolisant Impurity 9;4-Chlorophenylpropanol;4-Chlorobenzenepropanol;Benzenepropanol, 4-chloro-;3-(4-CHLOROPHENYL)PROPANOL;3-(4'-CHLOROPHENYL)PROPANOL;3-(4-Chlorophenyl)propanol95%;3-(4-CHLOROPHENYL)PROPAN-1-OL;3-(4-Chlorophenyl)propanol 95%;2-(1-oxoheptyl)indene-1,3-dione

CBNumber:: CB1168752

Molecular Formula:: C9H11ClO

Molecular Weight:: 170.64

MDL Number:: MFCD00831102

MOL File:: 6282-88-8.mol

MSDS File:: SDS

Last updated:2026-05-27 23:11:04

Request For Quotation

3-(4-Chlorophenyl)propan-1-ol Properties

Boiling point	104°C 0,1mm
Density	1.151±0.06 g/cm3(Predicted)
refractive index	1.54
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
pka	15.03±0.10(Predicted)
color	Colorless to Yellow
InChI	InChI=1S/C9H11ClO/c10-9-5-3-8(4-6-9)2-1-7-11/h3-6,11H,1-2,7H2
InChIKey	ZHBIWFGGIKFSHZ-UHFFFAOYSA-N
SMILES	C1(CCCO)=CC=C(Cl)C=C1
CAS DataBase Reference	6282-88-8(CAS DataBase Reference)
FDA UNII	7WMK84NW9D
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H319

Precautionary statements

P264-P270-P280-P301+P312-P305+P351+P338-P337+P313

Hazard Codes

Risk Statements

36/37/38-41

Safety Statements

26-36/37/39-24/25-39

WGK Germany

WGK 3

HazardClass

IRRITANT

HS Code

2906290090

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2

REACH Registrations

Active

NFPA 704

	1
2		0

3-(4-Chlorophenyl)propan-1-ol price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	CDS003137	3-(4-Chlorophenyl)-1-propanol AldrichCPR	6282-88-8	500MG	$77.9	2026-04-30	Buy
TCI Chemical	C3527	3-(4-Chlorophenyl)propan-1-ol >98.0%(GC)	6282-88-8	1g	$31	2026-04-30	Buy
TCI Chemical	C3527	3-(4-Chlorophenyl)propan-1-ol >98.0%(GC)	6282-88-8	5g	$122	2026-04-30	Buy
TRC	TRC-C596505-5G	3-(4-Chlorophenyl)propan-1-ol	6282-88-8	5g	$161	2026-06-03	Buy
TRC	TRC-C596505-1G	3-(4-Chlorophenyl)propan-1-ol	6282-88-8	1g	$74	2026-06-03	Buy

Product number	Packaging	Price	Buy
CDS003137	500MG	$77.9	Buy
C3527	1g	$31	Buy
C3527	5g	$122	Buy
TRC-C596505-5G	5g	$161	Buy
TRC-C596505-1G	1g	$74	Buy

3-(4-Chlorophenyl)propan-1-ol Chemical Properties, Uses, Production

Chemical Properties

Colorless liquid.

Uses

3-(4-Chlorophenyl)propan-1-ol is used in preparation of 2-Oxo-2H-chromene-3-carboxylic Acid Amide derivatives as Aldo-Keto reductase inhibitors.

Definition

ChEBI: 3-(4-Chlorophenyl)propan-1-ol is an organochlorine compound.

Synthesis

1615-02-7

6282-88-8

General procedure for the synthesis of 3-(4-chlorophenyl)propan-1-ol from p-chlorocinnamic acid: yield range 23.3-88.0%. As an example, 3-(4-chlorophenyl)propan-1-ol (3c) was synthesized as follows: under nitrogen protection and an ice bath, a THF solution of 3-(4-chlorophenyl)acrylic acid (2c, 2.74 g, 15 mmol) was slowly added to a tetrahydrofuran (THF, 30 mL) suspension of lithium aluminium hydride (1.71 g, 45 mmol), and the addition process was controlled to be completed within 30 min. The addition process was controlled to be completed within 30 min. The reaction mixture was stirred to room temperature and then continued to reflux for 4 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the complete consumption of the raw materials, the reaction mixture was cooled to room temperature. Subsequently, methanol (15 mL) and water (15 mL) were added slowly and dropwise to quench the reaction and the pH was adjusted with 10% hydrochloric acid solution to 3. The crude product was extracted with ethyl acetate (3 x 30 mL), the organic layers were combined, dried with anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure. The resulting yellow oil was purified by silica gel column chromatography (eluent: n-hexane/ethyl acetate=4:1, v/v) to give a yellow oily target product in 54.7% yield. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 7.27-7.22 (m, 2H), 7.15-7.10 (m, 2H), 3.66 (t, J=6.4 Hz, 2H), 2.68 (t, J=7.44 Hz, 2H), 1.91-1.81 (m, 2H).

References

[1] Chinese Chemical Letters, 2016, vol. 27, # 4, p. 555 - 558
[2] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 7, p. 1849 - 1853
[3] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 18, p. 4752 - 4756

3-(4-Chlorophenyl)propan-1-ol synthesis

Synthesis of 3-(4-Chlorophenyl)propan-1-ol from 3-(4-Chlorophenyl)propanoic acid

3-(4-Chlorophenyl)propan-1-ol Preparation Products And Raw materials

Raw materials

Benzeneethanol, 4-chloro-b-methyl- 3-(4-chlorophenyl)prop-2-en-1-ol methyl (E)-3-(4-chlorophenyl)prop-2-enoate 3-(4-Chlorophenyl)propanoic acid Benzenepropanoic acid, 4-chloro-, Methyl ester

3-(4-Chloro-phenyl)-propionic acid ethyl ester Ethyl 4-chlorocinnamate 3-(4-Chloro-phenyl)-propionaldehyde p-Chlorocinnamaldehyde Formic acid

carbon monoxide Ethanol 4-Chlorostyrene

1of3

Preparation Products

3-(4'-Chlorophenyl)propyl chloride

3-(4-Chlorophenyl)propan-1-ol Suppliers

Global Suppliers ( 179)

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Guide Fine Material Co.Ltd.	0512-66627360 13914021065	706938434@qq.com	China	202	60
Taizhou Wealsun Biotech Co., Ltd	18351140886; 18351140886	wealsunbio@126.com	China	139	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Shanghai Sunway Pharmaceutical Technology Co., Ltd	13761987713	hxzheng@sunwaypharm.cn	China	8663	57
Hangzhou Sage Chemical Co., Ltd.	+86057186818502 13588463833	info@sagechem.com	China	10265	58

Supplier	Advantage
Suzhou Guide Fine Material Co.Ltd.	60
Taizhou Wealsun Biotech Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Energy Chemical	61
Capot Chemical Co., Ltd	66
Beijing Ouhe Technology Co., Ltd	60
Jia Xing Isenchem Co.,Ltd	66
Shanghai Hanhong Scientific Co.,Ltd.	64
Shanghai Sunway Pharmaceutical Technology Co., Ltd	57
Hangzhou Sage Chemical Co., Ltd.	58

View Latest Price from 3-(4-Chlorophenyl)propan-1-ol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-08-12	3-(4-Chlorophenyl)propan-1-ol 6282-88-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
	2019-12-20	3-(4-Chlorophenyl)propan-1-ol 6282-88-8	$1.00	1g	99%		Career Henan Chemical Co

3-(4-Chlorophenyl)propan-1-ol
6282-88-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

3-(4-Chlorophenyl)propan-1-ol
6282-88-8
$1.00
99%
Career Henan Chemical Co

3-(4-Chlorophenyl)propan-1-ol Spectrum

3-(4-Chlorophenyl)propan-1-ol(6282-88-8)¹HNMR 3-(4-Chlorophenyl)propan-1-ol(6282-88-8)FT-IR

6282-88-8 (3-(4-Chlorophenyl)propan-1-ol) Related Search:

tert-Butylchlorodiphenylsilane 1,2-Dichloro-4-(chloromethyl)benzene Triphenylmethyl Chloride Chlorodimethylphenylsilane Chlorophenylsilane

Chlorpropamide Propargyl alcohol Epichlorohydrin rubber 3-(4-Chlorophenyl)propanoic acid D-4-Chlorophenylalanine

DL-4-Chlorophenylalanine methyl ester hydrochloride 3,3,3-Tris(4-chlorophenyl)propionic acid COUMACHLOR BOC-D-4-Chlorophe Baclofen

DL-4-Chlorophenylalanine ethyl ester hydrochloride Chloropropanol, mixed isomers Chlorfenprop-methyl

1of4

3-(4-CHLOROPHENYL)PROPAN-1-OL 3-(4'-CHLOROPHENYL)PROPANOL 3-(4-CHLOROPHENYL)PROPANOL 3-(4-Chlorophenyl)propan-1-ol, 95+% 3-(4-Chlorophenyl)propanol 95% 2-(1-oxoheptyl)indene-1,3-dione 3-(4-Chlorophenyl)propanol95% Benzenepropanol, 4-chloro- 4-Chlorobenzenepropanol Pitolisant Impurity 9 3-(4-CHLOROPHENYL)PROPAN-1-OL 98% 4-Chlorophenylpropanol 6282-88-8 6288-88-8 C9H11O2 Phenyls & Phenyl-Het Phenyls & Phenyl-Het