THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
![THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID Structure](CAS/GIF/59944-76-2.gif)
- CAS No.
- 59944-76-2
- Chemical Name:
- THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
- Synonyms
- 2-Carboxythieno[2,3-b]pyridine;HIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID;THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
- CBNumber:
- CB1185555
- Molecular Formula:
- C8H5NO2S
- Molecular Weight:
- 179.2
- MDL Number:
- MFCD07371381
- MOL File:
- 59944-76-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Thieno[2,3-b]pyridine-2-carboxylic acid | JCA94476 | 5g | $354 |
| Thieno[2,3-b]pyridine-2-carboxylic acid ≥95% | OR15126 | 250mg | $22 |
| Thieno[2,3-b]pyridine-2-carboxylic acid ≥95% | OR15126 | 1g | $66 |
| Thieno[2,3-b]pyridine-2-carboxylic acid ≥95% | OR15126 | 5g | $321 |
| Thieno[2,3-b]pyridine-2-carboxylic acid 95+% | T12732 | 1g | $60 |
| More product size | |||
| Melting point | 293 °C |
|---|---|
| Boiling point | 397.4±22.0 °C(Predicted) |
| Density | 1.508±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| form | solid |
| pka | 2.33±0.30(Predicted) |
| color | Off-white |
| InChI | InChI=1S/C8H5NO2S/c10-8(11)6-4-5-2-1-3-9-7(5)12-6/h1-4H,(H,10,11) |
| InChIKey | XGCSHAYMNOFFNA-UHFFFAOYSA-N |
| SMILES | C12SC(C(O)=O)=CC1=CC=CN=2 |
| CAS DataBase Reference | 59944-76-2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P271 | |||||||||
| Hazard Codes | Xi | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2934999090 | |||||||||
| NFPA 704 |
|
THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | JCA94476 | Thieno[2,3-b]pyridine-2-carboxylic acid | 59944-76-2 | 5g | $354 | 2026-06-04 | Buy |
| Apolloscientific | OR15126 | Thieno[2,3-b]pyridine-2-carboxylic acid ≥95% | 59944-76-2 | 250mg | $22 | 2026-06-04 | Buy |
| Apolloscientific | OR15126 | Thieno[2,3-b]pyridine-2-carboxylic acid ≥95% | 59944-76-2 | 1g | $66 | 2026-06-04 | Buy |
| Apolloscientific | OR15126 | Thieno[2,3-b]pyridine-2-carboxylic acid ≥95% | 59944-76-2 | 5g | $321 | 2026-06-04 | Buy |
| Synthonix | T12732 | Thieno[2,3-b]pyridine-2-carboxylic acid 95+% | 59944-76-2 | 1g | $60 | 2026-05-06 | Buy |
THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
Thieno[2,3-b]pyridine-2-carboxylic Acid is a useful reagent in study of neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for treatment of Alzheimer’s disease.
Definition
ChEBI: Thieno[2,3-b]pyridine-2-carboxylic acid is a thienopyridine.
Synthesis
![Methyl thieno[2,3-b]pyridine-2-carboxylate](/CAS/GIF/154650-88-1.gif)
154650-88-1
![THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID](/CAS/GIF/59944-76-2.gif)
59944-76-2
Methyl thieno[2,3-b]pyridine-2-carboxylate (C101, 0.700 g, 3.63 mmol) was used as a raw material and dissolved in a solvent mixture of methanol (15 mL) and water (3 mL). At room temperature, 2N sodium hydroxide solution (1.82 mL, 3.63 mmol) was added dropwise and the reaction mixture was stirred for 24 hours. Upon completion of the reaction, the mixture was concentrated under vacuum to remove most of the solvent. Subsequently, water (40 mL) was added to dissolve the residue. The resulting solution was acidified to pH 4 with concentrated hydrochloric acid, at which point thieno[2,3-b]pyridine-2-carboxylic acid (C102) precipitated as a white precipitate. The precipitate was collected by filtration to give the target product in 85% yield. The product was analyzed by mass spectrometry (EI) and showed a molecular ion peak m/z of 179 (M+), which is consistent with the theoretical value of the molecular formula C8H5NO2S.
References
[1] Patent: US2003/153595, 2003, A1
[2] Patent: US2003/45540, 2003, A1
[3] Patent: US2012/190674, 2012, A1. Location in patent: Page/Page column 91
THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35405 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49859 | 58 |
| Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | 3684455296@qq.com | China | 9285 | 58 |
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