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MYCALOLIDE B

CAS No.
122752-21-0
Chemical Name:
MYCALOLIDE B
Synonyms
MYCALOLIDE B;Mycalolide B, Mycale sp.;MYCALOLIDE B, MYCALE SPECIES;4-O-Acetyl-21-O-de(aminocarbonyl)-23,24-didehydro-39,46-dinor-6-deoxo-25-deoxy-6-(2,3-dimethoxy-1-oxopropoxy)-25-oxokabiramide C;Propanoic acid, 2,3-dimethoxy-, (1R,2S,3R,4R,5E)-3-(acetyloxy)-6-(formylmethylamino)-1-[(3S,4S)-5-[(10S,11R,13E,16S,20S,21R,22S,24E)-16-hydroxy-10,22-dimethoxy-11,21-dimethyl-12,18-dioxo-3,7,19,27-tetraoxa-29,30,31-triazatetracyclo[24.2.1.12,5.16,9]hentriaconta-2(31),4,6(30),8,13,24,26(29),28-octaen...
CBNumber:
CB1196858
Molecular Formula:
C52H74N4O17
Molecular Weight:
1027.16
MDL Number:
MFCD34567089
MOL File:
122752-21-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:09
Product description Number Pack Size Price
Mycalolide B 98% 6563 20ug $190

MYCALOLIDE B Properties

alpha -53.4℃ (D) (c=1.3 CHCl3)
storage temp. -20°C
solubility Soluble in DMSO (up to 20 mg/ml)
form Clear to white solid
color White
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

MYCALOLIDE B price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AvaChem 6563 Mycalolide B 98% 122752-21-0 20ug $190 2026-05-22 Buy
Product number Packaging Price Buy
6563 20ug $190 Buy

MYCALOLIDE B Chemical Properties,Uses,Production

Description

Mycalolide B (122752-21-0) is a novel marine natural product which binds to actin in a 1:1 molar ratio (Kd=13-20 nM).1It selectively and completely depolymerizes F-actin to G-actinviaa novel mechanism different from that of the cytochalasin D.2It is a novel and specific inhibitor of actomyosin ATPase.3

References

[1] SHUICHI SAITO. Mycalolide B, a novel actin depolymerizing agent.[J]. The Journal of Biological Chemistry, 1994, 38 1: 29710-29714. DOI:10.1016/s0021-9258(18)43938-5
[2] A. SUGIDACHI. Inhibition of Rat Platelet Aggregation by Mycalolide-B, a Novel Inhibitor of Actin Polymerization with a Different Mechanism of Action from Cytochalasin-D[J]. Thrombosis and haemostasis, 1998, 79 1: 614-619. DOI:10.1055/s-0037-1614955
[3] MASATOSHI HORI . Mycalolide-B, a novel and specific inhibitor of actomyosin ATPase isolated from marine sponge[J]. FEBS Letters, 1993, 322 2: Pages 151-154. DOI:10.1016/0014-5793(93)81557-g

MYCALOLIDE B Preparation Products And Raw materials

Raw materials

Preparation Products

MYCALOLIDE B Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19936 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9804 58
Enzo Biochem Inc Enzo Biochem Inc. 13797054060 Enzoname@qq.com China 6174 58
Santa Cruz Biotechnology Inc 021-60936350 scbt@scbt.com China 6594 58
MYCALOLIDE B MYCALOLIDE B, MYCALE SPECIES Mycalolide B, Mycale sp. 4-O-Acetyl-21-O-de(aminocarbonyl)-23,24-didehydro-39,46-dinor-6-deoxo-25-deoxy-6-(2,3-dimethoxy-1-oxopropoxy)-25-oxokabiramide C Propanoic acid, 2,3-dimethoxy-, (1R,2S,3R,4R,5E)-3-(acetyloxy)-6-(formylmethylamino)-1-[(3S,4S)-5-[(10S,11R,13E,16S,20S,21R,22S,24E)-16-hydroxy-10,22-dimethoxy-11,21-dimethyl-12,18-dioxo-3,7,19,27-tetraoxa-29,30,31-triazatetracyclo[24.2.1.12,5.16,9]hentriaconta-2(31),4,6(30),8,13,24,26(29),28-octaen... 122752-21-0 C52H74N4O17