6-Carboxytetramethylrhodamine N-hydroxysuccinimide ester
- CAS No.
- 150810-68-7
- Chemical Name:
- 6-Carboxytetramethylrhodamine N-hydroxysuccinimide ester
- Synonyms
- 5-TAMRA,SE, >95%;5-Carboxytetramethylrhodamine succinimidyl ester;CS-2126;5-TAMRASE;5-TAMRA-SEor5-TAMRA-NHS;5-TAMRA SE (Orange Red);5-TAMRA Azide (CCT-1245);5-TAMRA-SE, 10 mM in DMSO;5-TAMRA N-Succinimidyl Ester;5-TAMRA,SE [5-Carboxytetramethylrhodamine, SE]
- CBNumber:
- CB1207615
- Molecular Formula:
- C29H25N3O7
- Molecular Weight:
- 527.53
- MDL Number:
- MFCD07366710
- MOL File:
- 150810-68-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
|---|---|
| solubility | DMF: soluble |
| form | A solid |
| color | Pale purple to purple |
| Appearance | Dark red amorphous solid |
| InChIKey | VWFRSNKRTNUMET-UHFFFAOYSA-N |
| SMILES | C(C1C=C(C(=O)ON2C(CCC2=O)=O)C=CC=1C1=C2C=CC(N(C)C)=CC2=[O+]C2C=C(N(C)C)C=CC1=2)(=O)[O-] |
| UNSPSC Code | 12352116 |
| NACRES | NA.32 |
6-Carboxytetramethylrhodamine N-hydroxysuccinimide ester price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 53048 | 5-Carboxy-tetramethylrhodamine N-succinimidyl ester BioReagent,suitableforfluorescence | 150810-68-7 | 1mg | $182 | 2026-04-30 | Buy |
| Sigma-Aldrich | 53048 | 5-Carboxy-tetramethylrhodamine N-succinimidyl ester BioReagent,suitableforfluorescence | 150810-68-7 | 5mg | $616 | 2026-04-30 | Buy |
| TCI Chemical | T2808 | 5-TAMRA SE | 150810-68-7 | 5MG | $134 | 2026-04-30 | Buy |
| TCI Chemical | T2808 | 5-TAMRA SE | 150810-68-7 | 25MG | $399 | 2026-04-30 | Buy |
| Cayman Chemical | 28509 | 5-Carboxytetramethylrhodamine succinimidyl ester ≥90% | 150810-68-7 | 1mg | $41 | 2026-04-30 | Buy |
6-Carboxytetramethylrhodamine N-hydroxysuccinimide ester Chemical Properties,Uses,Production
Description
5-Carboxytetramethylrhodamine succinimidyl ester (5-TAMRA-SE) is an amine-reactive fluorescent probe. It has been used in double site-directed peptide modification to label proteinase substrates for use in FRET assays. It quenches lucifer yellow CH fluorescence by greater than 90% in uncleaved proteinase substrates, which allows for the detection of enzyme-cleaved substrates by an increase in fluorescence intensity. It has also been used in the synthesis of fluorescent derivatives of a variety of compounds, including the antibiotic ampicillin , nucleotide diphosphate uridine-5’-diphosphate (UDP; ), and the progesterone receptor antagonist RU486 (mifepristone; ). 5-TAMRA-SE displays excitation maxima ranging from 540 to 560 nm and an emission maximum of 580 nm.
Uses
Amine-reactive form of 5-carboxytetramethylrhodamine single isomer.
Uses
Amine-Reactive Fluorescent Probe for labeling of DNA and RNA
storage
Store at -20°C
References
[1] KIERAN F. GEOGHEGAN. Site-directed double fluorescent tagging of human renin and collagenase (MMP-1) substrate peptides using the periodate oxidation of N-terminal serine. An apparently general strategy for provision of energy-transfer substrates for proteases[J]. Bioconjugate Chemistry Bioconjugate, 1993, 4 6: 537-544. DOI: 10.1021/bc00024a017
[2] ADAM B. SHAPIRO* Mark S Janelle Comita Prevoir. 5-Carboxytetramethylrhodamine-Ampicillin Fluorescence Anisotropy-Based Assay of Escherichia coli Penicillin-Binding Protein 2 Transpeptidase Inhibition[J]. ACS Infectious Diseases, 2019, 5 6: 863-872. DOI: 10.1021/acsinfecdis.8b00351
[3] JUN QI Pablo S Michelle Oppenheimer. Fluorescence Polarization Binding Assay for Aspergillus fumigatus Virulence Factor UDP-Galactopyranose Mutase.[J]. Enzyme Research, 2011, 2011: 513905. DOI: 10.4061/2011/513905
[4] ROY WEINSTAIN. Fluorescent Ligand for Human Progesterone Receptor Imaging in Live Cells[J]. Bioconjugate Chemistry Bioconjugate, 2013, 24 5: 766-771. DOI: 10.1021/bc3006418
Abs/Em Maxima
553/575 nm
Excitation / Emission Maximum
546 nm/580 nm
Extinction Coefficient
92,000
Microscopy Laser Line
532 nm or 555 nm
Flow Cytometry Laser Line
532 nm or 555 nm
Spectrally Similar Dyes
Alexa Fluor® 555, CF® 555, DyLight® 549
6-Carboxytetramethylrhodamine N-hydroxysuccinimide ester Preparation Products And Raw materials
Raw materials
Preparation Products
6-Carboxytetramethylrhodamine N-hydroxysuccinimide ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Okeanos Tech Co,. Ltd. | 010-62651721 18610486005 | minghui.yu@okeanos.com.cn | China | 495 | 60 |
| Shanghai Annengjian Biomedical Technology Co., LTD | 021-68781987 13818305065 | sales@energybiopharma.com | China | 782 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Nanjing Search Biotech Co., Ltd | +86-025-81682922 +86-13515111588 | sales@searchbio.com.cn | China | 137 | 68 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| ChemPep, Inc. | +1 (888) 615-9178 / (561) 791-8787 | service@chempep.com | United States | 2138 | 57 |
| Nanjing Asian Chemical Co., Ltd. | +86 (25) 82263158 | China | 262 | 60 | |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
View Lastest Price from 6-Carboxytetramethylrhodamine N-hydroxysuccinimide ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 5-carboxytetramethylrhodamine succinimidyl ester
150810-68-7
|
1KG | 98% | 20Tons | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-07-15 | 5-TAMRA-SE
150810-68-7
|
$71.00-237.00 | 97.96% | 10g | TargetMol Chemicals Inc. |
-
- 5-carboxytetramethylrhodamine succinimidyl ester
150810-68-7
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-TAMRA-SE
150810-68-7
- $71.00-237.00
- 97.96%
- TargetMol Chemicals Inc.
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