2-(4-Formylphenyl)acetic acid
- CAS No.
- 34841-47-9
- Chemical Name:
- 2-(4-Formylphenyl)acetic acid
- Synonyms
- 4-Formylbenzeneacetic acid;14-Formylbenzeneacetic acid;4-carboxymethyl benzaldehyde;Benzeneacetic acid, 4-forMyl-;2-(4-Formylphenyl)acetic acid
- CBNumber:
- CB12199394
- Molecular Formula:
- C9H8O3
- Molecular Weight:
- 164.16
- MDL Number:
- MFCD09998872
- MOL File:
- 34841-47-9.mol
- MSDS File:
- SDS
| Melting point | 131 °C |
|---|---|
| Boiling point | 349.2±17.0 °C(Predicted) |
| Density | 1.277±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 4.06±0.10(Predicted) |
| InChI | InChI=1S/C9H8O3/c10-6-8-3-1-7(2-4-8)5-9(11)12/h1-4,6H,5H2,(H,11,12) |
| InChIKey | AGPZPJHWVWZCMG-UHFFFAOYSA-N |
| SMILES | C1(CC(O)=O)=CC=C(C=O)C=C1 |
| FDA UNII | 8DJ2L7EJC7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
2-(4-Formylphenyl)acetic acid price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | CX1079 | 2-(4-FORMYLPHENYL)ACETIC ACID 97% | 34841-47-9 | 0.25G | $79 | 2026-04-30 | Buy |
| AstaTech | CX1079 | 2-(4-FORMYLPHENYL)ACETIC ACID 97% | 34841-47-9 | 1G | $177 | 2026-04-30 | Buy |
| AstaTech | CX1079 | 2-(4-FORMYLPHENYL)ACETIC ACID 97% | 34841-47-9 | 5G | $637 | 2026-04-30 | Buy |
| Biosynth | JBA84147 | 2-(4-formylphenyl)acetic acid | 34841-47-9 | 0.5g | $318.6 | 2026-06-04 | Buy |
| Biosynth | JBA84147 | 2-(4-formylphenyl)acetic acid | 34841-47-9 | 5g | $1121 | 2026-06-04 | Buy |
2-(4-Formylphenyl)acetic acid Chemical Properties, Uses, Production
Synthesis
13737-36-5
34841-47-9
The general procedure for the synthesis of 2-(4-formylphenyl)acetic acid from 4-(bromomethyl)phenylacetic acid was as follows: 1. Preparation of Intermediate 4: To a mixed solution of 2-[4-(bromomethyl)phenyl]acetic acid (770 mg, 3.36 mmol) in ethanol (6 mL) and water (6 mL) was added hexamethylenetetramine (1.26 g, 9.0 mmol). 2. The reaction mixture was heated to reflux for 4 hours. 3. Concentrated hydrochloric acid (1.5 mL) was slowly added to the mixture under reflux. 4. Continue heating and refluxing for 30 minutes, then cool to room temperature. 5. Water (20 mL) and dichloromethane (20 mL) were added, and the organic phase was separated and filtered through hydrophobic filter paper. 6. The solvent was removed by vacuum to afford the title compound 2-(4-formylphenyl)acetic acid as an off-white solid (479 mg, 87% yield). 7. The product was analyzed by 1H NMR. 7. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 10.01 (s, 1H), 7.86 (d, J = 7.9 Hz, 2H), 7.47 (d, J = 7.9 Hz, 2H), 3.75 (s, 2H).
References
[1] Patent: WO2014/86849, 2014, A1. Location in patent: Page/Page column 81; 82
[2] Patent: US2014/155428, 2014, A1. Location in patent: Paragraph 0469 - 0471
[3] Patent: WO2015/185128, 2015, A1. Location in patent: Page/Page column 46; 47
[4] Organic Letters, 2008, vol. 10, # 20, p. 4589 - 4592
[5] Patent: WO2014/202580, 2014, A1. Location in patent: Page/Page column 80
2-(4-Formylphenyl)acetic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
2-(4-Formylphenyl)acetic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Thunder Biological Technology Co., Ltd. | 18621609968 | 1162686636@qq.com | China | 1034 | 58 |
| Hangzhou Chemtrue Bio-Tech Co.,Ltd. | 19967494293 | sales@chemtrue-bio.com | China | 303 | 58 |
| Chengdu D-innovation Pharmaceutical Co.，LTD | 028-85929779 18881048017 | chenxuanruo@d-innovation.com | China | 208 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Hangzhou Read Chemical Co., Ltd | 15306818081 | sales@freemindpharm.com | China | 50 | 58 |
| Cochemical Ltd. | 029-86115547 17791676824 | sales@cochemical.com | China | 3014 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Yancheng KangdiSen Pharmaceutical Co., Ltd. | 13812573443;18052965989 | tongbenwan22@163.com | China | 1975 | 55 |
View Latest Price from 2-(4-Formylphenyl)acetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 2-(4-Formylphenyl)acetic acid
34841-47-9
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-06-08 | 2-(4-Formylphenyl)acetic acid
34841-47-9
|
1kg | 99% | 1 | Jinan Ruitong Biotech Co., Ltd. | ||
 |
2024-07-31 | 2-(4-Formylphenyl)acetic acid
34841-47-9
|
$1.00 | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd |
-
- 2-(4-Formylphenyl)acetic acid
34841-47-9
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-(4-Formylphenyl)acetic acid
34841-47-9
- 99%
- Jinan Ruitong Biotech Co., Ltd.
-
- 2-(4-Formylphenyl)acetic acid
34841-47-9
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
