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Ethyl (4-forMylphenyl)acetate

Ethyl (4-forMylphenyl)acetate Structure
Ethyl (4-forMylphenyl)acetate structure
CAS No.
43153-12-4
Chemical Name:
Ethyl (4-forMylphenyl)acetate
Synonyms
Ethyl 2-(4-formylphenyl)acetate;Ethyl 4-formylbenzeneacetate;Ethyl (4-forMylphenyl)acetate;BENZENEACETIC ACID, 4-FORMYL-, ETHYL ESTER
CBNumber:
CB42710554
Molecular Formula:
C11H12O3
Molecular Weight:
192.21
MDL Number:
MOL File:
43153-12-4.mol
MSDS File:
SDS
Last updated:2026-05-28 05:16:53
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Ethyl (4-forMylphenyl)acetate Properties

Boiling point 300.6±17.0 °C(Predicted)
Density 1.127±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Ethyl (4-forMylphenyl)acetate price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS116088 Ethyl 2-(4-formylphenyl)acetate 95% 43153-12-4 1g $252 2026-06-04 Buy
Activate Scientific AS116088 Ethyl 2-(4-formylphenyl)acetate 95% 43153-12-4 5g $726 2026-06-04 Buy
Matrix Scientific 301209 Ethyl 2-(4-formylphenyl)acetate 43153-12-4 250.00mg $71 2026-05-19 Buy
Matrix Scientific 301209 Ethyl 2-(4-formylphenyl)acetate 43153-12-4 1.00g $173 2026-05-19 Buy
Matrix Scientific 301209 Ethyl 2-(4-formylphenyl)acetate 43153-12-4 5.00g $504 2026-05-19 Buy
Product number Packaging Price Buy
AS116088 1g $252 Buy
AS116088 5g $726 Buy
301209 250.00mg $71 Buy
301209 1.00g $173 Buy
301209 5.00g $504 Buy

Ethyl (4-forMylphenyl)acetate Chemical Properties, Uses, Production

Synthesis

4-Formylphenylboronic acid

87199-17-5

Ethyl bromoacetate

105-36-2

Ethyl (4-forMylphenyl)acetate

43153-12-4

GENERAL STEPS: To a screw-capped tube, 4-formylphenylboronic acid (450 mg, 3 mmol), ethyl bromoacetate (0.22 mL, 2 mmol), potassium carbonate (830 mg, 6 mmol), tris(dibenzylideneacetone)dipalladium (Pd2(dba)3, 46 mg, 0.05 mmol), tris(1-naphthyl)phosphine (62 mg, 0.15 mmol), water (0.5 mL) and tetrahydrofuran (THF, 4.5 mL). The reaction mixture was degassed with nitrogen for 5 min and then the reaction was stirred at 65 °C in an oil bath for 18 h. The reaction was carried out in the presence of a nitrogen gas. After completion of the reaction, it was cooled to room temperature, diluted with ethyl acetate (50 mL) and washed with water (2 x 50 mL). The organic phase was filtered through a phase separator and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography eluting with a gradient of 0-20% ethyl acetate/isohexane solution to afford the target product ethyl 2-(4-formylphenyl) acetate as a colorless oil (327 mg, 57% yield).1H NMR (400 MHz, CDCl3) δ: 9.99 (s, 1H), 7.83 (d, J = 8.0 Hz, 2H), 7.45 (d, J = 8.0 Hz, 2H), 4.19-4.12 (m, 2H), 3.70 (s, 2H), 1.28-1.20 (m, 3H).LCMS (Method 1): [MH+] = 193, retention time 3.58 min.

References

[1] Tetrahedron, 2010, vol. 66, # 42, p. 8238 - 8241
[2] Chemical Communications, 2001, # 7, p. 669 - 670
[3] Patent: WO2014/86852, 2014, A1. Location in patent: Page/Page column 67; 68
[4] Patent: US2014/155427, 2014, A1. Location in patent: Page/Page column

Ethyl (4-forMylphenyl)acetate Preparation Products And Raw materials

Raw materials

4-Formylphenylboronic acid Ethyl bromoacetate Water Tri(1-naphthyl)phosphine Potassium carbonate
Tetrahydrofuran Tris(dibenzylideneacetone)dipalladium

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Preparation Products

Ethyl (4-forMylphenyl)acetate Suppliers

Global Suppliers ( 30)
Supplier Tel Email Country ProdList Advantage
Beijing Eternalchem Co,. Ltd. 010-59484199 18611897322;18611897322; sales@eternalchem.com China 1993 60
Struchem Co., Ltd. 0512-63009836 18994340901 helen@struchem.com China 3970 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9787 55
Shanghai Zhen Li Biological Technology Co., Ltd 021-16621358918; 18516310516;16621358918;13045646768 zhenlipharma888@163.com China 19060 58
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
Beijing Minruida Technology Co., Ltd. 010-82387566 sales@mreda.com.cn China 19323 58
Shanghai Thunder Biological Technology Co., Ltd. 18621609968 1162686636@qq.com China 1030 58
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Win-Win chemical CO., Limited +86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14301 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Supplier Advantage
Beijing Eternalchem Co,. Ltd. 60
Struchem Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Shanghai Zhen Li Biological Technology Co., Ltd 58
Aikon International Limited 58
Beijing Minruida Technology Co., Ltd. 58
Shanghai Thunder Biological Technology Co., Ltd. 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Win-Win chemical CO., Limited 58
Career Henan Chemica Co 58

Ethyl (4-forMylphenyl)acetate Spectrum

Ethyl (4-forMylphenyl)acetate(43153-12-4)1HNMR

43153-12-4 (Ethyl (4-forMylphenyl)acetate) Related Search:

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Ethyl (4-forMylphenyl)acetate BENZENEACETIC ACID, 4-FORMYL-, ETHYL ESTER Ethyl 4-formylbenzeneacetate Ethyl 2-(4-formylphenyl)acetate 43153-12-4