(-)-Pyrenophorol
- CAS No.
- 22248-41-5
- Chemical Name:
- (-)-Pyrenophorol
- Synonyms
- Pyrenophorol;(-)-Pyrenophorol;(-)-Pyrenophorol;(3E,5S,8R,11E,13S,16R)-;(-)-5,13-Dihydroxy-8,16-dimethyl-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione;(3E,5S,8R,11E,13S,16R)-5,13-Dihydroxy-8,16-dimethyl-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione;1,9-Dioxacyclohexadeca-3,11-diene-2,10-dione, 5,13-dihydroxy-8,16-dimethyl-, (3E,5S,8R,11E,13S,16R)-
- CBNumber:
- CB12227646
- Molecular Formula:
- C16H24O6
- Molecular Weight:
- 312.36
- MDL Number:
- MFCD18379612
- MOL File:
- 22248-41-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H319 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P321-P330-P362+P364-P337+P313-P501 | |||||||||
| NFPA 704 |
|
(-)-Pyrenophorol price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28100 | Pyrenophorol ≥98% | 22248-41-5 | 1mg | $294 | 2026-04-30 | Buy |
| Usbiological | 207364 | (-)-Pyrenophorol ≥98%(HPLC) | 500ug | $425 | 2026-06-03 | Buy | |
| Usbiological | 207364 | (-)-Pyrenophorol ≥98%(HPLC) | 1mg | $588 | 2026-06-03 | Buy | |
| ChemScene | CS-0062718 | Pyrenophorol | 22248-41-5 | 1mg | $678 | 2026-06-04 | Buy |
| Adipogen Life Sciences | BVT-0289-M001 | Pyrenophorol ≥98%(HPLC) | 1mg | $230 | 2026-05-06 | Buy |
(-)-Pyrenophorol Chemical Properties, Uses, Production
Description
Pyrenophorol is a fungal metabolite that has been found in Alternaria and has diverse biological activities. It inhibits human topoisomerase II α when used at concentrations of 75 and 100 μM. It is active against S. cerevisiae (MIC = 4 μM) and M. violaceum. Pyrenophorol induces leaf necrosis and chlorophyll retention in wild oats when used at a concentration of 64 μM.
Uses
The macrolide dilactone Pyrenophorol n anti-fungal antibiotic produced by the plant pathogenic fungi Pyrenophora avenue and Stemphylium radicinum, which is closely related structurally to (-)- Pyrenophorol
Uses
Pyrenophorol is a simple macrocyclic dilactone produced by a number of species of pathogenic fungi, including Byssochlamys, Stenphyllum, Alternaria and Drechslera, first reported in the late 1960s. Pyrenophorol exhibits antibiotic, herbicidal and anthelmintic properties, and is a weak inhibitor of propyl endopeptidases. Pyrenophorol inhibits seed germination but once the seed is germinated, pyrenophlorol enhances root development but causes abnormal chlorophyll retention in leaf sections.
Uses
The macrolide dilactone Pyrenophorol was originally isolated from Byssochlamys niveah and Stemphylium radicinum. Pyrenophorol was moderately active against the fungus Microbotryum violaceum. It is an anti-fungal antibiotic produced by the plant pathogenic fungi Pyrenophora avenue and Stemphylium radicinum, which is closely related structurally to (-)-Pyrenophorol.
Definition
ChEBI: Pyrenophorol is a macrolide.
References
[1] KATHARINA JAROLIM. Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyrase[J]. Archives of Toxicology, 2016, 91 4: 2007-2016. DOI: 10.1007/s00204-016-1855-z
[2] MARK W. SUMARAH . Antifungal metabolites from fungal endophytes of Pinus strobus[J]. Phytochemistry, 2011, 72 14: Pages 1833-1837. DOI: 10.1016/j.phytochem.2011.05.003
[3] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
(-)-Pyrenophorol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4578 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4372 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8857 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
View Latest Price from (-)-Pyrenophorol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Pyrenophorol
22248-41-5
|
$668.00 | 10g | TargetMol Chemicals Inc. |
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- Pyrenophorol
22248-41-5
- $668.00
- TargetMol Chemicals Inc.
