ChemicalBook >> CAS DataBase List >>5,6,7,8-Tetrahydroquinolin-8-amine

5,6,7,8-Tetrahydroquinolin-8-amine

5,6,7,8-Tetrahydroquinolin-8-amine structure

CAS No.: 298181-83-6

Chemical Name:: 5,6,7,8-Tetrahydroquinolin-8-amine

Synonyms: 8-Amino-5;AKOS BB-8710;5,6,7,8-Tetrahydro-8-quinolinamine;5,6,7,8-tetrahydroquinolin-2-amine;8-quinolinamine,5,6,7,8-tetrahydro;5,6,7,8-Tetrahydroquinolin-8-amine;8-AMino-5,6,7,8-tetrahydroquinoline;5,6,7,8-Tetrahydro-8-aminoquinoline;5,6,7,8-TETRAHYDRO-QUINOLIN-8-YLAMINE;8-Quinolinamine,5,6,7,8-tetrahydro-(9CI)

CBNumber:: CB1240562

Molecular Formula:: C9H12N2

Molecular Weight:: 148.21

MDL Number:: MFCD08234982

MOL File:: 298181-83-6.mol

MSDS File:: SDS

Last updated:2026-09-12 18:49:05

Request For Quotation

5,6,7,8-Tetrahydroquinolin-8-amine Properties

Boiling point	277.3±28.0 °C(Predicted)
Density	1.081±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	8.93±0.20(Predicted)
Appearance	Light brown to brown Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
HS Code	2933998090

5,6,7,8-Tetrahydroquinolin-8-amine price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR930035	5,6,7,8-Tetrahydroquinolin-8-amine 96%	298181-83-6	100mg	$44	2026-06-04	Buy
Apolloscientific	OR930035	5,6,7,8-Tetrahydroquinolin-8-amine 96%	298181-83-6	250mg	$62	2026-06-04	Buy
Apolloscientific	OR930035	5,6,7,8-Tetrahydroquinolin-8-amine 96%	298181-83-6	1g	$123	2026-06-04	Buy
Apolloscientific	OR930035	5,6,7,8-Tetrahydroquinolin-8-amine 96%	298181-83-6	5g	$442	2026-06-04	Buy
Matrix Scientific	119687	5,6,7,8-Tetrahydroquinolin-8-amine	298181-83-6	250.00mg	$202	2026-05-18	Buy

Product number	Packaging	Price	Buy
OR930035	100mg	$44	Buy
OR930035	250mg	$62	Buy
OR930035	1g	$123	Buy
OR930035	5g	$442	Buy
119687	250.00mg	$202	Buy

5,6,7,8-Tetrahydroquinolin-8-amine Chemical Properties, Uses, Production

Synthesis Reference(s)

Synthetic Communications, 33, p. 3497, 2003 DOI: 10.1081/SCC-120024729

Synthesis

8-(Hydroxyimino)-5,6,7,8-tetrahydroquinoline

58509-59-4

298181-83-6

General procedure for the synthesis of 5,6,7,8-tetrahydro-8-aminoquinolines from 6,7-dihydroquinolin-8(5H)-one oxime: 6,7-dihydro-8(5H)-quinolinone oxime (0.50 g, 3.1 mmol) was dissolved in 35 mL of methanol and 50 mg 10% Pd/C catalyst was added. The catalytic hydrogenation reaction was carried out at 50 psi hydrogen pressure. After 18 hours of reaction, the hydrogen in the reaction system was replaced with nitrogen and the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated to dryness under reduced pressure to give 0.42 g (92% yield) of 5,6,7,8-tetrahydro-8-aminoquinoline as a purple oil.1H NMR (CDCl3) δ: 8.39 (d, 1H), 7.36 (d, 1H), 7.04 (m, 1H), 4.00 (t, 1H), 2.88-2.67 (m, 2H), 2.18 (m, 1H), 2.03-1.62 (m, 5H).

References

[1] Patent: WO2006/20415, 2006, A1. Location in patent: Page/Page column 112
[2] Synthetic Communications, 2003, vol. 33, # 20, p. 3497 - 3502
[3] Organic Process Research and Development, 2008, vol. 12, # 5, p. 823 - 830
[4] Chemical Communications, 2016, vol. 52, # 38, p. 6423 - 6426

5,6,7,8-Tetrahydroquinolin-8-amine Preparation Products And Raw materials

Raw materials

6,7-Dihydro-5H-quinolin-8-one 8-(Hydroxyimino)-5,6,7,8-tetrahydroquinoline Quinoline, 8-azido-5,6,7,8-tetrahydro- Methanol Hydrogen

Preparation Products

5,6,7,8-Tetrahydroquinolin-8-amine Suppliers

Global Suppliers ( 91)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Cuisen Pharmaceutical Technology Co., Ltd.	13472757003	yongnan.wang@cendrix.cn	China	974	65
Atop-Pharma (Shanghai) Technology Co., Ltd.	+86 (21) 5196-9732		China	996	57
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29977	65
Shanghai Witofly Chemical Co.,Ltd		sales@witofly.com	China	2853	52
Shanghai Yolne Chemical Co., Ltd.	021-62960152	934678158@qq.com	China	9886	55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.	+86-28-85122536 85324413	market@astatech.cn	China	8016	55
Shijiazhuang Lickon PharmaTech Co., Ltd.	031185291771 13832391721	yaofeng2005@163.com	China	947	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Shanghai Xingui Biotechnology Co., Ltd.	15121041756	xingui2022@126.com	China	9954	58
Shanghai HuanChuan Industry Co.,Ltd.	021-61478794	sales@hcshhai.com	China	9781	50

Supplier	Advantage
Shanghai Cuisen Pharmaceutical Technology Co., Ltd.	65
Atop-Pharma (Shanghai) Technology Co., Ltd.	57
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
Shanghai Witofly Chemical Co.,Ltd	52
Shanghai Yolne Chemical Co., Ltd.	55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.	55
Shijiazhuang Lickon PharmaTech Co., Ltd.	58
Bide Pharmatech Ltd.	60
Shanghai Xingui Biotechnology Co., Ltd.	58
Shanghai HuanChuan Industry Co.,Ltd.	50

View Latest Price from 5,6,7,8-Tetrahydroquinolin-8-amine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-20	5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE 298181-83-6	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
	2019-07-06	5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE 298181-83-6	$1.00	1KG	98%	1kg,5kg,100kg	Career Henan Chemical Co

5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE
298181-83-6
$1.10
99.00%
Dideu Industries Group Limited

5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE
298181-83-6
$1.00
98%
Career Henan Chemical Co

5,6,7,8-Tetrahydroquinolin-8-amine Spectrum

5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE(298181-83-6)¹HNMR

298181-83-6 (5,6,7,8-Tetrahydroquinolin-8-amine) Related Search:

5,6,7,8-Tetrahydroquinolin-8-ol 8-Quinolinamine,5,6,7,8-tetrahydro-,(8R)-(9CI) 8-Quinolinamine,5,6,7,8-tetrahydro-,(8S)-(9CI) 1-methyl-1,2,3,4-tetrahydroquinolin-7-amine 8-Aminoquinoline

5,6,7,8-Tetrahydroquinolin-8-amine 6''-Amino-1,2,3,4-tetrahydroquinoline 5,6,7,8-tetrahydroquinolin-6-amine (R)-5,6,7,8-tetrahydroquinolin-5-amine 1-(Cyclopropylcarbonyl)-1,2,3,4-tetrahydroquinolin-7-amine

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1of4

5,6,7,8-TETRAHYDRO-QUINOLIN-8-YLAMINE AKOS BB-8710 8-Quinolinamine,5,6,7,8-tetrahydro-(9CI) 8-quinolinamine,5,6,7,8-tetrahydro 5,6,7,8-tetrahydroquinolin-2-amine 5,6,7,8-Tetrahydro-8-quinolinamine 8-AMino-5,6,7,8-tetrahydroquinoline 5,6,7,8-tetrahydroquinolin-8-amine hydrochloride 8-Amino-5 5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE ISO 9001：2015 REACH 5,6,7,8-Tetrahydro-8-aminoquinoline 5,6,7,8-Tetrahydroquinolin-8-amine 298181-83-6 Quinoline Derivertives AMINEPRIMARY PYRIDINE