2-Aminobenzo[b]thiophene-3-carbonitrile
![2-Aminobenzo[b]thiophene-3-carbonitrile Structure](CAS2/GIF/18774-47-5.gif)
- CAS No.
- 18774-47-5
- Chemical Name:
- 2-Aminobenzo[b]thiophene-3-carbonitrile
- Synonyms
- 2-Aminobenzo[b]thiophene-3-carbonitrile;2-Amino-1-benzothiophene-3-carbonitrile;Benzo[b]thiophene-3-carbonitrile, 2-amino-;2-aminobenzo[b]thiophene-3-carbonitrile - [AC80454];2-AMINOBENZO[B]THIOPHENE-3-CARBONITRILE ISO 9001：2015 REACH
- CBNumber:
- CB12468744
- Molecular Formula:
- C9H6N2S
- Molecular Weight:
- 174.22
- MDL Number:
- MFCD00464272
- MOL File:
- 18774-47-5.mol
- MSDS File:
- SDS
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
|---|---|
| Appearance | Off-white to light brown Solid |
| CAS DataBase Reference | 18774-47-5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-Aminobenzo[b]thiophene-3-carbonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 309368 | 2-Aminobenzo[b]thiophene-3-carbonitrile | 18774-47-5 | 250.00mg | $73 | 2026-05-19 | Buy |
| Matrix Scientific | 309368 | 2-Aminobenzo[b]thiophene-3-carbonitrile | 18774-47-5 | 1.00g | $200 | 2026-05-19 | Buy |
| Matrix Scientific | 309368 | 2-Aminobenzo[b]thiophene-3-carbonitrile | 18774-47-5 | 5.00g | $977 | 2026-05-19 | Buy |
| Synthonix | AC80454 | 2-aminobenzo[b]thiophene-3-carbonitrile 98% | 18774-47-5 | 250mg | $63.5 | 2026-05-06 | Buy |
| Synthonix | AC80454 | 2-aminobenzo[b]thiophene-3-carbonitrile 98% | 18774-47-5 | 500mg | $97.7 | 2026-05-06 | Buy |
2-Aminobenzo[b]thiophene-3-carbonitrile Chemical Properties, Uses, Production
Application
2-Aminobenzo[B]thiophene-3-carboxynitrile is a nitrile compound that can be used as an organic solvent.
Synthesis
![Benzo[b]thiophene-3-carbonitrile, 2-nitro- (9CI)](/CAS/GIF/612505-78-9.gif)
612505-78-9
![2-AMINOBENZO[B]THIOPHENE-3-CARBONITRILE](/CAS2/GIF/18774-47-5.gif)
18774-47-5
A mixture of 2-nitro-1-benzothiophene-3-carbonitrile (134 mg, 0.656 mmol) with 10% Pd/C (70 mg, 0.066 mmol) was dissolved in methanol (3 mL) under nitrogen protection. The gas in the flask was replaced with hydrogen and the reaction was stirred under hydrogen atmosphere for 24 hours. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad and the diatomaceous earth pad was washed with methanol (10 mL) and ethyl acetate (10 mL). The filtrate was concentrated under reduced pressure and dried under high vacuum to afford the target product 2-aminobenzo[b]thiophene-3-carbonitrile (109 mg, 95% yield). The product molecular ion peak m/z was 175 ([M+H]+) with a retention time of 0.77 min as analyzed by LC-MS.
References
[1] Patent: WO2011/25799, 2011, A1. Location in patent: Page/Page column 105
[2] Patent: WO2004/14895, 2004, A1. Location in patent: Page 104
2-Aminobenzo[b]thiophene-3-carbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
2-Aminobenzo[b]thiophene-3-carbonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
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| Sichuan BoYou Biotechnology Co., Ltd. | 028-65791793 18140026355 | 568470422@qq.com | China | 9961 | 58 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
