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Oxazole-2-carbaldehyde

CAS No.
65373-52-6
Chemical Name:
Oxazole-2-carbaldehyde
Synonyms
RARECHEM AK ML 0184;OXAZOLE-2-CARBALDEHYDE;2-OXAZOLECARBOXALDEHYDE;1,3-oxazole-2-carbaldehyde;1,3-Oxazole-2-carboxaldehyde;2-Oxazolecarboxaldehyde (9CI);1,3-Oxazole-2-carboxaldehyde 97%;2-Oxazolecarboxaldehyde (9CI, ACI);Oxazole-2-carbaldehyde ISO 9001:2015 REACH
CBNumber:
CB1247819
Molecular Formula:
C4H3NO2
Molecular Weight:
97.07
MDL Number:
MFCD03412587
MOL File:
65373-52-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:19:36

Oxazole-2-carbaldehyde Properties

Boiling point 182.5±23.0 °C(Predicted)
Density 1.258±0.06 g/cm3(Predicted)
storage temp. -20°C, stored under nitrogen
form low melting solid
pka -1.86±0.10(Predicted)
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Warning
Hazard statements  H226-H302+H312+H332-H319-H335
Precautionary statements  P271-P260-P280
Hazard Codes  Xi,F
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  2934999090

Oxazole-2-carbaldehyde price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 230634 2-Oxazolecarboxaldehyde ≥96% ≥96%(Assay) 65373-52-6 100mg $262 2026-06-03 Buy
Usbiological 230634 2-Oxazolecarboxaldehyde ≥96% ≥96%(Assay) 65373-52-6 250mg $375 2026-06-03 Buy
Usbiological 230634 2-Oxazolecarboxaldehyde ≥96% ≥96%(Assay) 65373-52-6 1g $658 2026-06-03 Buy
Apolloscientific OR14993 1,3-Oxazole-2-carboxaldehyde 97% 65373-52-6 250mg $48 2026-06-04 Buy
Apolloscientific OR14993 1,3-Oxazole-2-carboxaldehyde 97% 65373-52-6 1g $173 2026-06-04 Buy
Product number Packaging Price Buy
230634 100mg $262 Buy
230634 250mg $375 Buy
230634 1g $658 Buy
OR14993 250mg $48 Buy
OR14993 1g $173 Buy

Oxazole-2-carbaldehyde Chemical Properties, Uses, Production

Synthesis

Oxazole

288-42-6

N,N-Dimethylformamide

68-12-2

Oxazole-2-carbaldehyde

65373-52-6

To a tetrahydrofuran solution of oxazole F-1 (800 mg, 11.58 mmol) was slowly added a hexane solution of 1.6 M n-butyllithium (7.2 mL, 11.58 mmol) at -78 °C. After the reaction mixture was stirred at this temperature for 1 h, a tetrahydrofuran (8 mL) solution of N,N-dimethylformamide (0.89 mmol, 11.58 mmol) was added. Subsequently, the reaction system was gradually warmed to room temperature and stirring was continued overnight. Upon completion of the reaction, the reaction was quenched with methanol, filtered through Dowex 50W x 8-200 resin (H+ type, 1:1 mass ratio of resin to oxazole F-1) and washed with methanol. The filtrates were combined and concentrated to give the crude products oxazole-2-carboxaldehyde F-2a and F-1a. The crude product was purified by column chromatography (using 100-200 mesh silica gel, eluent 2% ether/dichloromethane) to give purified oxazole-2-carboxaldehyde (900 mg, 80% yield) as a light brown liquid (Rf = 0.7, 2% ether/dichloromethane system). The product could be used directly in the subsequent reaction without further characterization.

References

[1] Patent: WO2011/35009, 2011, A1. Location in patent: Page/Page column 45-46
[2] Patent: WO2008/61109, 2008, A2. Location in patent: Page/Page column 62
[3] Patent: WO2005/102998, 2005, A1. Location in patent: Page/Page column 31
[4] Journal of Photochemistry and Photobiology A: Chemistry, 2016, vol. 316, p. 95 - 103

Oxazole-2-carbaldehyde Preparation Products And Raw materials

Global Suppliers ( 122)
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Jinan Trio PharmaTech Co., Ltd. 0531-88811783 sales@trio-pharmatech.com China 1856 62
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Shanghai ChriChem Co., Ltd. 021-54880687 China 510 55

View Latest Price from Oxazole-2-carbaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Oxazole-2-carbaldehyde pictures 2019-12-24 Oxazole-2-carbaldehyde
65373-52-6
$1.00 1KG 98%min Career Henan Chemical Co
1,3-Oxazole-2-carboxaldehyde 1,3-oxazole-2-carbaldehyde 2-OXAZOLECARBOXALDEHYDE 2-Oxazolecarboxaldehyde (9CI) RARECHEM AK ML 0184 OXAZOLE-2-CARBALDEHYDE 1,3-Oxazole-2-carboxaldehyde 97% Oxazole-2-carbaldehyde ISO 9001:2015 REACH 2-Oxazolecarboxaldehyde (9CI, ACI) 65373-52-6 Oxazoles, Isoxazoles & Benzoxazoles Oxazoles, Isoxazoles & Benzoxazoles ALDEHYDE Aldehydes