Oxazole-4-carbaldehyde
- CAS No.
- 118994-84-6
- Chemical Name:
- Oxazole-4-carbaldehyde
- Synonyms
- 1,3-Oxazole-4-carboxaldehyde;4-FORMYLOXAZOLE;4-Formyl-1,3-oxazole;oxazol-4-carbaldehyde;OXAZOLE-4-CARBALDEHYDE;4-OXAZOLECARBOXALDEHYDE;Oxazole-4-carboxaldehyde;4-Oxazolecarboxaldehyde>1,3-oxazole-4-carbaldehyde;4-Oxazolecarboxaldehyde 97%
- CBNumber:
- CB6194334
- Molecular Formula:
- C4H3NO2
- Molecular Weight:
- 97.07
- MDL Number:
- MFCD02179512
- MOL File:
- 118994-84-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Oxazolecarboxaldehyde 97% | 697915 | 250mg | $218 |
| 4-Oxazolecarboxaldehyde 97% | 697915 | 1g | $328 |
| 4-Oxazolecarboxaldehyde >98.0%(GC) | O0453 | 200mg | $91 |
| 4-Oxazolecarboxaldehyde >98.0%(GC) | O0453 | 1g | $312 |
| 4-Oxazolecarboxaldehyde Asreported | 286293 | 250mg | $347 |
| More product size | |||
| Melting point | 57-61 °C |
|---|---|
| Boiling point | 184.7±13.0 °C(Predicted) |
| Density | 1.258±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | -1.49±0.10(Predicted) |
| color | Yellow |
| InChI | InChI=1S/C4H3NO2/c6-1-4-2-7-3-5-4/h1-3H |
| InChIKey | JBWIIXBEPINWPB-UHFFFAOYSA-N |
| SMILES | O1C=C(C=O)N=C1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317-H319 |
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22-36-43 |
| Safety Statements | 26-36/37 |
| WGK Germany | 3 |
| HS Code | 2934999090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Sens. 1 |
Oxazole-4-carbaldehyde price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 697915 | 4-Oxazolecarboxaldehyde 97% | 118994-84-6 | 250mg | $218 | 2026-04-30 | Buy |
| Sigma-Aldrich | 697915 | 4-Oxazolecarboxaldehyde 97% | 118994-84-6 | 1g | $328 | 2026-04-30 | Buy |
| TCI Chemical | O0453 | 4-Oxazolecarboxaldehyde >98.0%(GC) | 118994-84-6 | 200mg | $91 | 2021-12-16 | Buy |
| TCI Chemical | O0453 | 4-Oxazolecarboxaldehyde >98.0%(GC) | 118994-84-6 | 1g | $312 | 2021-12-16 | Buy |
| Usbiological | 286293 | 4-Oxazolecarboxaldehyde Asreported | 118994-84-6 | 250mg | $347 | 2026-06-03 | Buy |
Oxazole-4-carbaldehyde Chemical Properties,Uses,Production
Uses
Oxazole-4-carboxaldehyde is mainly used in laboratory organic synthesis and in chemical and pharmaceutical research and development processes.
Synthesis
155742-48-6
118994-84-6
The general procedure for the synthesis of oxazole-4-carbaldehyde from 4-oxazolemethanol was as follows: a solution of anhydrous dichloromethane (200 mL) with dimethylsulfoxide (DMSO, 19.3 mL, 272 mmol) was added slowly and dropwise to a solution of anhydrous dichloromethane (200 mL) with oxalyl chloride (17.3 mL, 204 mmol) at -63 °C. The reaction mixture was stirred at -63 °C for 15 min before adding an anhydrous dichloromethane (200 mL) solution of 4-oxazole methanol (13.5 g, 204 mmol) with a controlled dropwise addition time of 15 min. Stirring was continued at -63 °C for 60 min, followed by the addition of triethylamine (Et3N, 53.1 mL, 381 mmol). The reaction mixture was gradually warmed up to room temperature. Upon completion of the reaction, the mixture was combined with 10% aqueous citric acid solution and extracted with dichloromethane (4 times) and ethyl acetate (2 times). The organic phases were combined, washed with a small amount of saturated aqueous sodium bicarbonate solution and extracted again with dichloromethane (3 times) and ethyl acetate (3 times). All organic phases were combined, dried with magnesium sulfate (MgSO4), filtered and the solvent was removed under reduced pressure. The residue was purified by column chromatography (eluent: ether/petroleum ether, ratio tapered from 1:1 to 2:1, to 4:1 and finally 1:0) to give oxazole-4-carbaldehyde (11.9 g, 86% yield). Thin layer chromatography (TLC) showed an Rf value of 0.65 (Expander: methanol/dichloromethane, 1:9).
References
[1] Patent: WO2006/21402, 2006, A1. Location in patent: Page/Page column 34
[2] Patent: WO2005/105802, 2005, A1. Location in patent: Page/Page column 109-110
Oxazole-4-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Hubei Ipure Biology Co., Ltd | +8618062405514 | ada@ipurechemical.com | China | 10224 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9628 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
View Lastest Price from Oxazole-4-carbaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-01-15 | 4-Oxazolecarboxaldehyde
118994-84-6
|
1KG | 98.0% | 100 tons | Honest Joy Holdings Limited | ||
 |
2021-07-02 | Oxazole-4-carbaldehyde
118994-84-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | Oxazole-4-carbaldehyde
118994-84-6
|
$1.00 | 1kg | 98% | 200kg | Career Henan Chemical Co |
-
- 4-Oxazolecarboxaldehyde
118994-84-6
- $0.00
- 98.0%
- Honest Joy Holdings Limited
-
- Oxazole-4-carbaldehyde
118994-84-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Oxazole-4-carbaldehyde
118994-84-6
- $1.00
- 98%
- Career Henan Chemical Co
