Imidazo[1,2-a]pyrazine-2-carboxylic acid
![Imidazo[1,2-a]pyrazine-2-carboxylic acid Structure](CAS/GIF/77112-53-9.gif)
- CAS No.
- 77112-53-9
- Chemical Name:
- Imidazo[1,2-a]pyrazine-2-carboxylic acid
- Synonyms
- Imidazo[1,2-a]pyrazine-2-carboxylic acid
- CBNumber:
- CB1248609
- Molecular Formula:
- C7H5N3O2
- Molecular Weight:
- 163.13
- MDL Number:
- MFCD08460077
- MOL File:
- 77112-53-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HazardClass | IRRITANT |
Imidazo[1,2-a]pyrazine-2-carboxylic acid price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 057562 | Imidazo[1,2-a]pyrazine-2-carboxylic acid | 77112-53-9 | 1.00g | $1008 | 2026-05-18 | Buy |
| Synthonix | K44878 | Imidazo[1,2-a]pyrazine-2-carboxylic acid 97% | 77112-53-9 | 100mg | $34 | 2026-05-06 | Buy |
| Synthonix | K44878 | Imidazo[1,2-a]pyrazine-2-carboxylic acid 97% | 77112-53-9 | 250mg | $38 | 2026-05-06 | Buy |
| Synthonix | K44878 | Imidazo[1,2-a]pyrazine-2-carboxylic acid 97% | 77112-53-9 | 1g | $40 | 2026-05-06 | Buy |
| Synthonix | K44878 | Imidazo[1,2-a]pyrazine-2-carboxylic acid 97% | 77112-53-9 | 5g | $170 | 2026-05-06 | Buy |
Imidazo[1,2-a]pyrazine-2-carboxylic acid Chemical Properties, Uses, Production
Synthesis
![ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE](/CAS/GIF/77112-52-8.gif)
77112-52-8
![IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID](/CAS/GIF/77112-53-9.gif)
77112-53-9
Lithium chloride monohydrate (6.50 g, 0.156 mol) was added to ethyl imidazo[1,2-a]pyrazine-2-carboxylate (9.73 g, 0.05 mol) in a mixed ethanol/water (400 mL/100 mL) solvent and the reaction was stirred at room temperature for 8 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The pH of the reaction mixture was adjusted to 3-4 with aqueous 1 N hydrochloric acid under cooling in an ice bath and a solid was precipitated. The precipitate was collected by filtration and washed sequentially with acetone and dichloromethane. The filter cake was dried at 50 °C and the residual solvent was removed under reduced pressure to afford imidazo[1,2-a]pyrazine-2-carboxylic acid (7.69 g, 9.4 mmol) in pink solid powder form in 93.7% yield.
References
[1] Patent: CN103965194, 2016, B. Location in patent: Paragraph 0214-0216
[2] Journal of Medicinal Chemistry, 1984, vol. 27, # 2, p. 206 - 212
[3] Farmaco, Edizione Scientifica, 1981, vol. 36, # 1, p. 61 - 80
Imidazo[1,2-a]pyrazine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shangchem Co., Ltd. | +86-21-68182121 | China | 881 | 52 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| skychemical Co.Ltd | 021-20958197 20965099 | sales@skychemical.com | China | 1182 | 57 |
| Kohn & Shawn Pharmatech Co.,Ltd | 0943-8293106 | sales@kyxpharma.com | China | 297 | 55 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Shanghai Carlow Chemicals Co., Ltd. | 21-33526724 18930996265 | info@carlowchem.com | China | 1996 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Nantong MYBio-pharm. Co., Ltd. | 0513-85921823 18662920231 | sales@ntminyanmedical.com | China | 4563 | 58 |
77112-53-9 (Imidazo[1,2-a]pyrazine-2-carboxylic acid) Related Search:
1of4
