3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester
- CAS No.
- 161833-42-7
- Chemical Name:
- 3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester
- Synonyms
- Methyl 3-amino-4-bromothiophene-2-formate;Methyl 3-amino-4-bromothiophen-2-carboxylate;3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester;3-Amino-4-bromothiophen-2-carboxylic acid methyl ester;3-Amino-4-bromo-2-thiophenecarboxylic acid methyl ester;2-Thiophenecarboxylic acid, 3-amino-4-bromo-, methyl ester;3-amino-4-bromo-2-Thiophenecarboxylic acid methyl ester (9CI ACI);2-Thiophenecarboxylic acid, 3-amino-4-bromo-, methyl ester (9CI, ACI)
- CBNumber:
- CB12550461
- Molecular Formula:
- C6H6BrNO2S
- Molecular Weight:
- 236.09
- MDL Number:
- MFCD09038329
- MOL File:
- 161833-42-7.mol
- MSDS File:
- SDS
| Boiling point | 333.6±37.0 °C(Predicted) |
|---|---|
| Density | 1.745±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| pka | -0.20±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C6H6BrNO2S/c1-10-6(9)5-4(8)3(7)2-11-5/h2H,8H2,1H3 |
| InChIKey | LWSWLXPUUCBUPI-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)SC=C(Br)C=1N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | M42859 | Methyl 3-amino-4-bromothiophene-2-carboxylate 95+% | 161833-42-7 | 100mg | $19 | 2026-05-06 | Buy |
| Synthonix | M42859 | Methyl 3-amino-4-bromothiophene-2-carboxylate 95+% | 161833-42-7 | 250mg | $25 | 2026-05-06 | Buy |
| Synthonix | M42859 | Methyl 3-amino-4-bromothiophene-2-carboxylate 95+% | 161833-42-7 | 1g | $30 | 2026-05-06 | Buy |
| Synthonix | M42859 | Methyl 3-amino-4-bromothiophene-2-carboxylate 95+% | 161833-42-7 | 5g | $80 | 2026-05-06 | Buy |
| Synthonix | M42859 | Methyl 3-amino-4-bromothiophene-2-carboxylate 95+% | 161833-42-7 | 10g | $130 | 2026-05-06 | Buy |
3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester Chemical Properties, Uses, Production
Synthesis
22288-78-4
161833-42-7
Example 2: Synthesis of 3-[(dimethylamino)diazenyl]-4-bromothiophene-2-carboxamide (Compound 2) Step a: Synthesis of methyl 3-amino-4-bromothiophene-2-carboxylate To a solution of methyl 3-aminothiophene-2-carboxylate (1 g, 6.36 mmol) in acetic acid (10 mL), a solution of bromine (0.32 mL, 6.36 mmol) in acetic acid (1 mL) was slowly added, and the addition process lasted for 5 min, and the reaction was carried out at room temperature. After addition, the reaction mixture was stirred at the same temperature for 16 hours. After completion of the reaction, the mixture was poured into ice-cold water and extracted with chloroform (3 x 100 mL). The organic layers were combined, washed sequentially with water and brine and dried over anhydrous sodium sulfate. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography with the eluent petroleum ether-ethyl acetate (95:5, v/v) to afford the target product methyl 3-amino-4-bromothiophene-2-carboxylate as a light yellow solid (0.5 g, 33% yield) with a melting point of 58-60°C. The residue was extracted with water and sodium sulfate. 1H NMR (400 MHz, CDCl3): δ 7.29 (s, 1H), 5.63 (br s, 2H), 3.85 (s, 3H).
References
[1] Bulletin of the Korean Chemical Society, 2016, vol. 37, # 9, p. 1406 - 1414
[2] Patent: WO2010/29577, 2010, A2. Location in patent: Page/Page column 28-29
[3] Patent: US2010/68178, 2010, A1. Location in patent: Page/Page column 12
[4] Patent: CN106167497, 2016, A. Location in patent: Paragraph 0162; 0163; 0164
[5] Patent: EP2708540, 2014, A1. Location in patent: Paragraph 0137
3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Yongsheng Pharmaceutical Technology Co., Ltd | 3307 18017383231 | 983544897@qq.com | China | 941 | 58 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Goodee Pharma Co., Ltd. | 0512-62956210 | yongyan@goodeepharma.com | China | 132 | 60 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from 3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2022-04-22 | 3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester
161833-42-7
|
98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd | |||
 |
2019-07-12 | 3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester
161833-42-7
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester
161833-42-7
- 98%min
- Shanghai Rlavie Technology Co ltd
-
- 3-AMino-4-broMo-thiophene-2-carboxylicacidMethylester
161833-42-7
- $1.00
- 99%
- Career Henan Chemical Co
