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VU 0364439

VU 0364439 Structure
VU 0364439 structure
CAS No.
1246086-78-1
Chemical Name:
VU 0364439
Synonyms
CS-629;VU 0364439;VU 0364439 10MG;VU 0364439, >=98%;VU 0364439 USP/EP/BP;VU0364439/VU-0364439;VU 0364439, 10 mM in DMSO;VU 0364439;VU0364439; VU-0364439;N-(3-Chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide;N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide
CBNumber:
CB12596591
Molecular Formula:
C18H13Cl2N3O3S
Molecular Weight:
422.29
MDL Number:
MFCD22378484
MOL File:
1246086-78-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:19:10
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VU 0364439 Properties

Density 1.538±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≥21.11 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form solid
pka 7.71±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

VU 0364439 price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16296 VU0364439 ≥98% 1246086-78-1 1mg $36 2026-04-30 Buy
Cayman Chemical 16296 VU0364439 ≥98% 1246086-78-1 5mg $120 2026-04-30 Buy
Cayman Chemical 16296 VU0364439 ≥98% 1246086-78-1 10mg $186 2026-04-30 Buy
Cayman Chemical 16296 VU0364439 ≥98% 1246086-78-1 50mg $587 2026-04-30 Buy
Usbiological 257065 VU 0364439 Asreported 1246086-78-1 10mg $446 2026-06-03 Buy
Product number Packaging Price Buy
16296 1mg $36 Buy
16296 5mg $120 Buy
16296 10mg $186 Buy
16296 50mg $587 Buy
257065 10mg $446 Buy

VU 0364439 Chemical Properties, Uses, Production

Uses

VU 0364439 is a mGlu4 positive allosteric modulator (PAM) (1,2).

IC 50

mGlu4 Receptor: 19.8 nM (EC50)

References

[1]. lucyna pomierny-chamioło, kinga rup, bartosz pomierny, et al. metabotropic glutamatergic receptors and their ligands in drug addiction. pharmacology & therapeutics, 2014, 142:281-305.
[2]. albert j. robichaud, darren w. engers, craig w. lindsley, et al. recent progress on the identification of metabotropic glutamate 4 receptor ligands and their potential utility as cns therapeutics. acs chemical neuroscience, 2011, 2:433-449.
[3]. colleen m. niswender, kari a. johnson, c. david weaver, et al. discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. mol. pharmacol., 2008, 74(5):1345-1358.
[4]. darren w. engers, patrick r. gentry, richard williams, et al. synthesis and sar of novel, 4-(phenylsulfamoyl)phenylacetamide mglu4 positive allosteric modulators (pams) identified by functional high-throughput screening (hts). bioorg. med. chem. lett., 2010, 20:5175-5178.

VU 0364439 Preparation Products And Raw materials

Raw materials

Preparation Products

VU 0364439 Suppliers

Global Suppliers ( 102)
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
GIHI CHEMICALS CO.,LTD 0086-571-86217390 Sales@gihichem.com China 858 58
AdooQ Bioscience CHINA 025-58849295 info@adooq.cn China 2981 60
Credit Asia Chemical Co., Ltd. +86 (21) 61124340 China 9739 58
Hubei Jusheng Technology Co.,Ltd 027-59599241 18871490274 1400878000@qq.com China 9506 58
Supplier Advantage
Shanghai Boyle Chemical Co., Ltd. 55
Dalian Meilun Biotech Co., Ltd. 58
Haoyuan Chemexpress Co., Ltd. 61
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
MedChemexpress LLC 58
Guangzhou Isun Pharmaceutical Co., Ltd 55
GIHI CHEMICALS CO.,LTD 58
AdooQ Bioscience CHINA 60
Credit Asia Chemical Co., Ltd. 58
Hubei Jusheng Technology Co.,Ltd 58

View Latest Price from VU 0364439 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
VU 0364439 pictures 2026-05-11 VU 0364439
1246086-78-1
 $40.00-123.00 97.90% 10g TargetMol Chemicals Inc.
  • VU 0364439 pictures
  • VU 0364439
    1246086-78-1
  • $40.00-123.00
  • 97.90%
  • TargetMol Chemicals Inc.

VU 0364439 Spectrum

VU 0364439(1246086-78-1)1HNMR

1246086-78-1 (VU 0364439) Related Search:

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VU 0365114 VU 0357121 VU 0360223

1of4

VU 0364439 2-PyridinecarboxaMide, N-[3-chloro-4-[[(2-chlorophenyl)aMino]sulfonyl]phenyl]- VU0364439/VU-0364439 N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide VU0364439 CS-629 VU 0364439, >=98% VU 0364439;VU0364439; VU-0364439 VU 0364439 10MG N-(3-Chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide VU 0364439 USP/EP/BP VU 0364439, 10 mM in DMSO 1246086-78-1 Inhibitors