2-PiperidineMethanol, (2S)-
- CAS No.
- 41373-39-1
- Chemical Name:
- 2-PiperidineMethanol, (2S)-
- Synonyms
- (S)-Piperidin-2-ylMethanol;[(2S)-2-piperidyl]methanol;(S)-2-Piperidinemethanol;(2S)-2-Piperidinemethanol;2-PiperidineMethanol, (2S)-;[(2S)-piperidin-2-yl]methanol;(2S)-2-PiperidineMethanol HCl
- CBNumber:
- CB12639124
- Molecular Formula:
- C6H13NO
- Molecular Weight:
- 115.17
- MDL Number:
- MFCD11036291
- MOL File:
- 41373-39-1.mol
- MSDS File:
- SDS
| Melting point | 66-68 °C |
|---|---|
| Boiling point | 221.2±0.0 °C(Predicted) |
| Density | 0.951±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 15.08±0.10(Predicted) |
| Appearance | Colorless to light yellow <66°C Solid,>68°C Liquid |
| optical activity | 16.267° (C=0.01 g/ml, ETOH) |
| InChI | InChI=1S/C6H13NO/c8-5-6-3-1-2-4-7-6/h6-8H,1-5H2/t6-/m0/s1 |
| InChIKey | PRAYXGYYVXRDDW-LURJTMIESA-N |
| SMILES | N1CCCC[C@H]1CO |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501 |
| HS Code | 2933399990 |
2-PiperidineMethanol, (2S)- price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR917897 | (2S)-Piperidin-2-ylmethanol 97% | 41373-39-1 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR917897 | (2S)-Piperidin-2-ylmethanol 97% | 41373-39-1 | 5g | $62 | 2026-06-04 | Buy |
| Apolloscientific | OR917897 | (2S)-Piperidin-2-ylmethanol 97% | 41373-39-1 | 10g | $117 | 2026-06-04 | Buy |
| Apolloscientific | OR917897 | (2S)-Piperidin-2-ylmethanol 97% | 41373-39-1 | 25g | $233 | 2026-06-04 | Buy |
| Apolloscientific | OR917897 | (2S)-Piperidin-2-ylmethanol 97% | 41373-39-1 | 100g | $845 | 2026-06-04 | Buy |
2-PiperidineMethanol, (2S)- Chemical Properties, Uses, Production
Synthesis
3105-95-1
41373-39-1
General procedure for the synthesis of (S)-piperidin-2-ylmethanol from L-2-piperidinic acid: BH3-DMS (62.0 mmol, 4.0 eq.) and BF3-Et2O (15.5 mmol, 1.0 eq.) were added to a solution of (2S)-piperidine-2-carboxylic acid (15.5 mmol, 1.0 eq.) in THF (50 ml) at 0 °C. The reaction mixture was refluxed for 14 hours. After completion of the reaction, the solvent was removed by concentration under reduced pressure, followed by slow dropwise addition of MeOH (40 ml) at 0 °C. Concentrated HCl (5 ml) was added to the mixture and refluxing was continued for 2 hours. The solvent was again concentrated to remove the solvent and the residue was stirred in a DCM solution of 10% isopropanol for 15 min and filtered. The filtrate was concentrated to dryness to give the white solid product (S)-piperidin-2-ylmethanol in 80% yield.
References
[1] Tetrahedron, 2013, vol. 69, # 51, p. 10876 - 10883
[2] Tetrahedron, 2013, vol. 69, # 30, p. 6129 - 6143
[3] Patent: US2010/173889, 2010, A1. Location in patent: Page/Page column 34
[4] Patent: US2009/253669, 2009, A1. Location in patent: Page/Page column 46-47
[5] Patent: US2009/264407, 2009, A1. Location in patent: Page/Page column 77
2-PiperidineMethanol, (2S)- Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Welt Chem. Co.,Ltd. | 531-87153728 13805401165 | xufeng192@126.com | China | 6027 | 58 |
| ForeChem (Nantong) Technology Co.,Ltd. | 513-85982855 18921614129 | sales@xianxingpharm.com | China | 2712 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Chengdu HappySyn Pharmaceutical Technology Co., Ltd. | 85114309 18982182443 | yangli@happysyn.com | China | 2310 | 55 |
| Shanghai LiangYi Fine Chemicals Co., Ltd. | 021-62594801 | shliangyi@liangyichem.com | China | 50 | 58 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Shijiazhuang Lickon PharmaTech Co., Ltd. | 031185291771 13832391721 | yaofeng2005@163.com | China | 947 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9848 | 55 |
