3-Oxo-cyclopentanecarbonitrile
- CAS No.
- 41171-91-9
- Chemical Name:
- 3-Oxo-cyclopentanecarbonitrile
- Synonyms
- 3-Cyanocyclopentanone;3-Oxo-cyclopentanecarbonitrile;Cyclopentanecarbonitrile, 3-oxo-;3-Oxocyclopentane-1-Carbonitrile
- CBNumber:
- CB12669729
- Molecular Formula:
- C6H7NO
- Molecular Weight:
- 109.13
- MDL Number:
- MFCD21184612
- MOL File:
- 41171-91-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Oxocyclopentane-1-carbonitrile | RBA17191 | 1g | $354 |
| 3-Oxocyclopentane-1-carbonitrile | RBA17191 | 10g | $2596 |
| 3-Oxocyclopentane-1-carbonitrile 98% | OR940018 | 100mg | $73 |
| 3-Oxocyclopentane-1-carbonitrile 98% | OR940018 | 250mg | $123 |
| 3-Oxocyclopentane-1-carbonitrile 98% | OR940018 | 1g | $336 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| WGK Germany | WGK 3 |
| HS Code | 2926907090 |
| Storage Class | 10 - Combustible liquids |
3-Oxo-cyclopentanecarbonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | RBA17191 | 3-Oxocyclopentane-1-carbonitrile | 41171-91-9 | 1g | $354 | 2026-06-05 | Buy |
| Biosynth | RBA17191 | 3-Oxocyclopentane-1-carbonitrile | 41171-91-9 | 10g | $2596 | 2026-06-05 | Buy |
| Apolloscientific | OR940018 | 3-Oxocyclopentane-1-carbonitrile 98% | 41171-91-9 | 100mg | $73 | 2026-06-04 | Buy |
| Apolloscientific | OR940018 | 3-Oxocyclopentane-1-carbonitrile 98% | 41171-91-9 | 250mg | $123 | 2026-06-04 | Buy |
| Apolloscientific | OR940018 | 3-Oxocyclopentane-1-carbonitrile 98% | 41171-91-9 | 1g | $336 | 2026-06-04 | Buy |
3-Oxo-cyclopentanecarbonitrile Chemical Properties,Uses,Production
Uses
3-Cyanocyclopentanone is used for catalytic enantioselective conjugate addition of cyanide to enones.
Definition
ChEBI: An alicyclic ketone that is cyclopentanone substituted at position 3 by a cyano group.
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 3455, 1973 DOI: 10.1021/jo00960a002
Synthesis
930-30-3
41171-91-9
General procedure for the synthesis of 3-oxocyclopentanecarbonitrile from 2-cyclopentenone: a mixed solution of 2-cyclopentenone (10 g, 122 mmol), potassium cyanide (9.5 g, 146 mmol), and triethylamine hydrochloride (25 g, 83 mmol) in methanol (150 mL) was stirred for 4 hours at room temperature. Upon completion of the reaction, the reaction mixture was concentrated; the residue was redissolved in ethyl acetate. The resulting solution was washed sequentially with water and saturated saline, dried over anhydrous sodium sulfate and concentrated. The residue was purified by silica gel column chromatography (petroleum ether: ethyl acetate = 5:1) to give 7.5 g of 3-oxocyclopentanecarbonitrile.1H NMR (400 MHz, CDCl3): δ 3.13-3.51 (m, 1H), 2.56-2.63 (m, 1H), 2.16-2.48 (m, 5H).
References
[1] Journal of Organic Chemistry, 1997, vol. 62, # 15, p. 5144 - 5155
[2] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 5, p. 2164 - 2167
[3] Patent: WO2013/28670, 2013, A1. Location in patent: Page/Page column 119; 120
3-Oxo-cyclopentanecarbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2028 | 58 | |
| Labnetwork lnc. | +86-27-50766799 +86-18062016861 | contact@labnetwork.com | China | 19981 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +86-15195660023 | 3899766280@qq.com | China | 26349 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
