Gancaonin I
- CAS No.
- 126716-36-7
- Chemical Name:
- Gancaonin I
- Synonyms
- Gancaonin I;4-[4,6-Dimethoxy-5-(3-methyl-2-buten-1-yl)-2-benzofuranyl]-1,3-benzenediol;1,3-Benzenediol, 4-[4,6-dimethoxy-5-(3-methyl-2-buten-1-yl)-2-benzofuranyl]-
- CBNumber:
- CB12681305
- Molecular Formula:
- C21H22O5
- Molecular Weight:
- 354.4
- MDL Number:
- MFCD27968675
- MOL File:
- 126716-36-7.mol
| Boiling point | 534.2±45.0 °C(Predicted) |
|---|---|
| Density | 1.212±0.06 g/cm3(Predicted) |
| pka | 8.75±0.35(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | 6XTP69UV3S |
Gancaonin I Chemical Properties,Uses,Production
Uses
Gancaonin I, an Isoflavone, exhibits moderate inhibition on human carboxylesterase 2 (hCES2A) with IC50 of 1.72 μM. Gancaonin I inhibits hCES2A-mediated fluorescein diacetate (FD) hydrolysis[1].
Definition
ChEBI: Gancaonin I is a member of the class of 1-benzofurans which consists of 1-benzofuran substituted by methoxy groups at positions 4 and 6, a prenyl group at position 5 and a 2,4-dihydroxyphenyl group at position 2. It has been isolated from Glycyrrhiza uralensis. It has a role as an antibacterial agent and a plant metabolite. It is a member of 1-benzofurans, an aromatic ether and a member of resorcinols. It derives from a hydride of a 1-benzofuran.
References
[1] Yun-Qing Song, et al. Discovery of hCES2A inhibitors from Glycyrrhiza inflate via combination of docking-based virtual screening and fluorescence-based inhibition assays. Food Funct. 2021 Jan 7;12(1):162-176. DOI:10.1039/d0fo02140g
Gancaonin I Preparation Products And Raw materials
Raw materials
Preparation Products
Gancaonin I Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10983 | 58 |
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| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7787 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15178 | 58 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6905 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |