Taurochenodeoxycholic acid sodium salt
- CAS No.
- 6009-98-9
- Chemical Name:
- Taurochenodeoxycholic acid sodium salt
- Synonyms
- SODIUM TAUROCHENODEOXYCHOLATE;taurochenodeoxycholic acid soduim salt;Taurochenodeoxycholic Acid D4 Sodium Salt;NSC681055;Ursodeoxycholic Impurity 15;Chenodeoxycholic Acid Impurity;TAUROCHENODEOXYCHOLIC ACID SODIUM;SODIUM TAUROCHENODEOXYCHOLIC ACID;Urosodeoxycholic Acid Impurity 15;Taurine goose deoxycholate sodium
- CBNumber:
- CB1277818
- Molecular Formula:
- C26H45NO6S.Na
- Molecular Weight:
- 522.7
- MDL Number:
- MFCD00036745
- MOL File:
- 6009-98-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 165-175 °C |
|---|---|
| storage temp. | room temp |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | <2 |
| color | White to Off-White |
| BRN | 3901205 |
| Stability | Hygroscopic |
| InChIKey | IYPNVUSIMGAJFC-UKYQSIPTNA-M |
| SMILES | [Na].[S](=O)(=O)(O)CCNC(=O)CC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@H]3O)C[C@@H](CC4)O)C)CC2)CC1)C)C |
| CAS DataBase Reference | 6009-98-9(CAS DataBase Reference) |
| FDA UNII | P2SD3PHQ3Y |
| UNSPSC Code | 41141802 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| HS Code | 29309090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Taurochenodeoxycholic acid sodium salt price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T6260 | Sodium taurochenodeoxycholate | 6009-98-9 | 100mg | $235 | 2026-04-30 | Buy |
| Sigma-Aldrich | T6260 | Sodium taurochenodeoxycholate | 6009-98-9 | 1g | $1070 | 2026-04-30 | Buy |
| Cayman Chemical | 20275 | Taurochenodeoxycholic Acid (sodium salt) ≥95% | 6009-98-9 | 50mg | $72 | 2026-04-30 | Buy |
| Cayman Chemical | 20275 | Taurochenodeoxycholic Acid (sodium salt) ≥95% | 6009-98-9 | 100mg | $129 | 2026-04-30 | Buy |
| Cayman Chemical | 20275 | Taurochenodeoxycholic Acid (sodium salt) ≥95% | 6009-98-9 | 500mg | $537 | 2026-04-30 | Buy |
Taurochenodeoxycholic acid sodium salt Chemical Properties, Uses, Production
Description
Taurochenodeoxycholic acid (TCDCA) is a taurine-conjugated form of the primary bile acid chenodeoxycholic acid (CDCA; ). Serum levels of TCDCA increase approximately 5-fold in within two hours and begin to decrease within four hours during an oral lipid tolerance test in humans. Serum levels of TCDCA are increased in patients with liver cirrhosis and may serve as a marker of disease progression.
Chemical Properties
Solid
Uses
Labeled Taurochenodeoxycholic Acid, intended for use as an internal standard for the quantification of Taurochenodeoxycholic Acid by GC- or LC-mass spectrometry.
Uses
Taurochenodeoxycholic Acid Sodium Salt is a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.
General Description
An ionic detergent used for solubilizing lipids and proteins.
in vivo
Taurochenodeoxycholic acid (12-Deoxycholyltaurine; TCDCA; 0.05, 0.1g/kg) sodium decreases the pulmonary coefficient in the model mice and reduces the pathological damages on their lungs; it can decrease the expression levels of TNF-α and TIMP-2 in pulmonary tissues in the pulmonary fibrosis mice and has no significant effects on MMP2[2].
Taurochenodeoxycholic acid sodium significantly normalizes the clinical inflammatory parameters, prevented indomethacin-induced increases in the biliary contents of secondary bile acids and hydrophobicity index, and tended to attenuate the intestinal inflammation[3].
Taurochenodeoxycholic acid sodium significantly suppresses paw swelling and polyarthritis index, increases the loss body weight and index of thymus and spleen, and amends radiologic changes in AA rats. The overproduction and mRNA expression of TNF-α, IL-1β and IL-6 are remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats[4].
IC 50
Microbial Metabolite; Human Endogenous Metabolite
References
[1] HOFMANN A F. The continuing importance of bile acids in liver and intestinal disease.[J]. Archives of internal medicine, 1999, 159 22: 2647-2658. DOI: 10.1001/archinte.159.22.2647
[2] A. SCHMID. Bile Acid Metabolome after an Oral Lipid Tolerance Test by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)[J]. PLoS ONE, 2016, 11 1. DOI: 10.1371/journal.pone.0148869
[3] XIAONING WANG. Serum Bile Acids Are Associated with Pathological Progression of Hepatitis B-Induced Cirrhosis[J]. Journal of Proteome Research, 2015, 15 4: 1126-1134. DOI: 10.1021/acs.jproteome.5b00217
Taurochenodeoxycholic acid sodium salt Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Endesa Bio-tech Co., Ltd. | 025-58862853 18915922038 | sales@endesachem.com | China | 590 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
View Latest Price from Taurochenodeoxycholic acid sodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | taurocholate
6009-98-9
|
1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-07-15 | Taurochenodeoxycholic acid sodium
6009-98-9
|
$46.00 | 99.56% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-22 | TAUROCHENODEOXYCHOLIC ACID SODIUM SALT
6009-98-9
|
$3.00 | 1g | 99.99 | 1000000 | Anhuyan (Hainan) Biotechnology Co., LTD |
-
- taurocholate
6009-98-9
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Taurochenodeoxycholic acid sodium
6009-98-9
- $46.00
- 99.56%
- TargetMol Chemicals Inc.
-
- TAUROCHENODEOXYCHOLIC ACID SODIUM SALT
6009-98-9
- $3.00
- 99.99
- Anhuyan (Hainan) Biotechnology Co., LTD
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