Tauroursodeoxycholic acid sodium salt
- CAS No.
- 35807-85-3
- Chemical Name:
- Tauroursodeoxycholic acid sodium salt
- Synonyms
- SODIUM TAUROURSODEOXYCHOLATE;TUDC;auroursodeoxycholate Sodium;Ursodeoxycholyltaurine sodium;Sodium Tauroursodesoxycholate;Tauroursodeoxycholate (Sodium);Urosodeoxycholic Acid Impurity 25;Taurocursodeoxycholic acid sodium;Sodium Tauroursodeoxycholate (TUDC);Sodium tauroursodesoxycholate, >=97%
- CBNumber:
- CB8459121
- Molecular Formula:
- C26H46NNaO6S
- Molecular Weight:
- 523.7
- MDL Number:
- MFCD00065451
- MOL File:
- 35807-85-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 173-175°C |
|---|---|
| alpha | +40~+50°(D/20℃) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly, Heated), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Pale Beige |
| Water Solubility | water: 100mg/mL |
| InChIKey | WSSCRQYICWZEFG-SXXADWEANA-N |
| SMILES | C[C@]12CC[C@]3([H])[C@]4(CC[C@@H](O)C[C@@]4([H])C[C@H](O)[C@@]3([H])[C@]1([H])CC[C@]2([H])[C@H](C)CCC(=O)NCCS(O)(=O)=O)C.[NaH] |&1:1,4,6,9,12,15,17,19,23,25,r| |
| FDA UNII | 6X4JLR867N |
| UNSPSC Code | 12352211 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P313-P337+P313-P362-P403+P233-P405-P501 |
| WGK Germany | 2 |
| RTECS | KI7372500 |
| HS Code | 2924297099 |
| Storage Class | 11 - Combustible Solids |
Tauroursodeoxycholic acid sodium salt price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T0266 | Sodium tauroursodeoxycholate | 35807-85-3 | 500mg | $625 | 2026-04-30 | Buy |
| Sigma-Aldrich | T0266 | Sodium tauroursodeoxycholate | 35807-85-3 | 1g | $1120 | 2026-04-30 | Buy |
| Sigma-Aldrich | 580549 | Tauroursodeoxycholic Acid, Sodium Salt Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins. | 35807-85-3 | 1 g | $240 | 2026-04-30 | Buy |
| Sigma-Aldrich | 580549 | Tauroursodeoxycholic Acid, Sodium Salt Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins. | 35807-85-3 | 5 g | $818 | 2026-04-30 | Buy |
| Cayman Chemical | 20277 | Tauroursodeoxycholic Acid (sodium salt) ≥95% | 35807-85-3 | 500mg | $65 | 2026-04-30 | Buy |
Tauroursodeoxycholic acid sodium salt Chemical Properties, Uses, Production
Chemical Properties
Off-White Solid
Uses
Tauroursodeoxycholic Acid Sodium Salt is a bile related salt for isolation of lipids and membrane-bound proteins. It is a sodium salt form of Tauroursodeoxycholic Acid which can be used in biological study of inhibition of alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption by glycyrrhizin and glycyrrhetinic acid.
Uses
Sodium tauroursodeoxycholate has been used in a study to assess whether ER stress is involved in palmitic acid upregulation (PA). It has also been used in a study to investigate its effect on Estradiol-17β-D-glucuronide (E-17G) induced cholestasis in female rats.
Uses
Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.
General Description
Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.
in vivo
The effects of Tauroursodeoxycholate (TUDCA) on proliferation and apoptosis of VSMCs in vivo are examined using immunohistochemistry. Tauroursodeoxycholate (10, 50, and 100 mg/kg) increases the caspase 3 activity of injured tissues in a dose-dependent manner, indicating that Tauroursodeoxycholate induces apoptosis of VSMCs in the neointima. Using the injured tissues, further examination and comparison of the phosphorylation level of ERK and MMP-9 expression is performed at 1 week after injury, compared with normal controls. Balloon injury increased both the phosphorylation of ERK and expression of MMP-9 in the tissues. Tauroursodeoxycholate (10, 50, and 100 mg/kg) inhibits phosphorylation of ERK and MMP-9 expression in a dose-dependent manner[1]. Tauroursodeoxycholate (TUDCA) is a hydrophilic bile acid. Tauroursodeoxycholate as a cytoprotective agent improves liver function and can prevent hepatocellular carcinoma by reducing ER stress and apoptosis. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3, caspase-12, C/EBP homologous protein, c-Jun N-terminal kinase (JNK), activating transcription factor 4 (ATF4), X-box binding protein (XBP), and eukaryotic initiation factor 2α (eIF2α) in Ang II induced ApoE-/- mice (p<0.05). Tauroursodeoxycholate reduces Angiotensin (Ang) II induced abdominal aortic aneurysm (AAA) formation in ApoE-/- mice. Tauroursodeoxycholate is used at a dose of 0.5 g/kg/day in treating Ang II induced ApoE-/- mice (ER stress inhibitor group). Systolic blood pressure (141.3±5.6 mmHg vs 145.9±8.9 mmHg; p>0.05) and total cholesterol levels (663.6±88.7 mg/dL vs 655.7±65.4 mg/dL; p>0 .05) do not differ between the AAA model group and Tauroursodeoxycholate group. In addition, maximum aortic diameter is significantly smaller in those in Tauroursodeoxycholate group compared with those in the AAA model group (0.95±0.03 mm vs 1.79±0.04 mm; p<0.05). AAA lesion areas are also smaller in those in Tauroursodeoxycholate group than in those in the AAA model group (0.37±0.03 mm2 vs 1.51±0.06 mm2; p<0.05)[2].
IC 50
ERK; Caspase-3; Caspase-12; Human Endogenous Metabolite
Tauroursodeoxycholic acid sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Endesa Bio-tech Co., Ltd. | 025-58862853 18915922038 | sales@endesachem.com | China | 590 | 58 |
| Hubei Weideli Chemical Reagent Co., Ltd. | 18327179646 | 18327179646@163.com | China | 1977 | 58 |
| Tenghua Tech | 13212769786 | 2024685872@qq.com | China | 139 | 58 |
| Huaibei Zhongmai Biotechnology Co., Ltd. | 18156107007 | 1475618467@qq.com | China | 48 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
View Latest Price from Tauroursodeoxycholic acid sodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-07 | TAUROURSODEOXYCHOLIC ACID SODIUM SALT
35807-85-3
|
1kg | 99%min | 2000KGS | HANGZHOU HAILAN CHEMICAL CO.,LTD. | ||
 |
2026-08-25 | Sodium tauroursodeoxycholate
35807-85-3
|
1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-08-20 | Tauroursodeoxycholate sodium
35807-85-3
|
$30.00-58.00 | 99.78% | 10g | TargetMol Chemicals Inc. |
-
- TAUROURSODEOXYCHOLIC ACID SODIUM SALT
35807-85-3
- $0.00
- 99%min
- HANGZHOU HAILAN CHEMICAL CO.,LTD.
-
- Sodium tauroursodeoxycholate
35807-85-3
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Tauroursodeoxycholate sodium
35807-85-3
- $30.00-58.00
- 99.78%
- TargetMol Chemicals Inc.
35807-85-3 (Tauroursodeoxycholic acid sodium salt) Related Search:
1of3
