Azido-PEG6-CH2CO2t-butyl ester
- CAS No.
- 297162-49-3
- Chemical Name:
- Azido-PEG6-CH2CO2t-butyl ester
- Synonyms
- N3-PEG6-COOtBu;N3-PEG6-CH2CO2tBu;Azido-PEG6-C1-Boc;N3-PEG6-CH2COOtBu;AZIDO-PEG6-CH2CO2TBU;Azido-PEG6-CH2COOtBu;Azido-PEG6-CH2COOH t-Bu Ester;Azido-PEG6-CH2CO2t-butyl ester;tert-Butyl 20-azido-3,6,9,12,15,18-hexaoxaic osanoate;N3-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-azido-, 1,1-dimethylethyl ester
- CBNumber:
- CB13062367
- Molecular Formula:
- C18H35N3O8
- Molecular Weight:
- 421.49
- MDL Number:
- MFCD27977491
- MOL File:
- 297162-49-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Azido-PEG6-CH2CO2t-butyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | BIPG1151 | Azido-PEG6-CH2CO2t-butyl ester 98% | 297162-49-3 | 250mg | $682 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1151 | Azido-PEG6-CH2CO2t-butyl ester 98% | 297162-49-3 | 500mg | $1265 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1151 | Azido-PEG6-CH2CO2t-butyl ester 98% | 297162-49-3 | 1g | $2302 | 2026-06-04 | Buy |
| BroadPharm | bp-22132 | Azido-PEG6-CH2CO2-t-Bu 98% | 297162-49-3 | 250MG | $340 | 2026-05-24 | Buy |
| BroadPharm | bp-22132 | Azido-PEG6-CH2CO2-t-Bu 98% | 297162-49-3 | 500MG | $650 | 2026-05-24 | Buy |
Azido-PEG6-CH2CO2t-butyl ester Chemical Properties, Uses, Production
Description
Azido-PEG6-CH2CO2-t-Bu contain an azide group and a t-butyl ester. PEG spacer increases reagent's solubility in aqueous media. The azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry. The t-butyl protected carboxyl group can be deprotected under acidic condition.
Uses
Azido-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG6-CH2CO2t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 9999 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| SuZhou Medinoah Co.,LTD. | 0512-69561983 13914027025 | zhang_q@medinoah.com | China | 3925 | 58 |
| Shandong utilizing biological technology co., LTD | 18669728830 15966937598 | 3407650895@qq.com | China | 5185 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
View Latest Price from Azido-PEG6-CH2CO2t-butyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-07-24 | N3-PEG6-CH2COOtBu
297162-49-3
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. |
-

- N3-PEG6-CH2COOtBu
297162-49-3
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.





