Azadirachtin | 11141-17-6

Azadirachtin Properties

Melting point	159°C
alpha	D -53° (c = 0.5 in CHCl3)
Boiling point	792.4±60.0 °C(Predicted)
Density	1.51
storage temp.	−20°C
solubility	DMSO (Sparingly), Methanol (Slightly)
form	Solid
pka	9.78±0.70(Predicted)
color	White to Pale Yellow
Merck	13,896
Henry's Law Constant	3.5×10¹⁹ mol/(m³Pa) at 25℃, HSDB (2015)
Stability	Light Sensitive
Major Application	agriculture environmental
InChIKey	TWGPOIQWWGNBKW-POEZYEDVSA-N
SMILES	[H]C1([H])C2OC3([H])OC=CC3(O)C1C4(C)OC24[C@@]5(C)[C@@H](O)[C@@H]6OC[C@]7([C@H](C[C@H](OC(=O)C(C)=CC)[C@]8(COC(O)([C@H]58)C(=O)OC)[C@@]67[H])OC(C)=O)C(=O)OC
LogP	1.090
CAS DataBase Reference	11141-17-6
FDA UNII	O4U1SAF85H
Pesticides Freedom of Information Act (FOIA)	Azadirachtin
EPA Substance Registry System	Azadirachtin A (11141-17-6)
UNSPSC Code	41116107
NACRES	NA.28

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS09
Signal word	Warning
Hazard statements	H317-H410
Precautionary statements	P261-P272-P273-P280-P302+P352-P333+P313
PPE	Eyeshields, Gloves, type N95 (US)
Risk Statements	22
Safety Statements	22-45
RIDADR	3077
WGK Germany	3
HazardClass	9
PackingGroup	III
HS Code	13021920
Storage Class	11 - Combustible Solids
Hazard Classifications	Aquatic Acute 1 Aquatic Chronic 1 Skin Sens. 1B
Hazardous Substances Data	11141-17-6(Hazardous Substances Data)

Azadirachtin price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHL89574	Azadirachtin phyproof? Reference Substance	11141-17-6	5MG	$527	2026-04-30	Buy
Sigma-Aldrich	A7430	Azadirachtin ~95%	11141-17-6	0.5mg	$161	2026-04-30	Buy
Cayman Chemical	21893	Azadirachtin ≥95%	11141-17-6	1mg	$63	2026-04-30	Buy
Cayman Chemical	21893	Azadirachtin ≥95%	11141-17-6	5mg	$242	2026-04-30	Buy
Cayman Chemical	21893	Azadirachtin ≥95%	11141-17-6	10mg	$363	2026-04-30	Buy

Product number	Packaging	Price	Buy
PHL89574	5MG	$527	Buy
A7430	0.5mg	$161	Buy
21893	1mg	$63	Buy
21893	5mg	$242	Buy
21893	10mg	$363	Buy

Azadirachtin Chemical Properties, Uses, Production

Description

Kernel extracts from the Indian neem tree (Azadirachta indica) have insecticidal and insect-repellent properties. The key active ingredient is azadirachtin, a nortriterpenoid that exhibits insect growth regulator effects but no adulticidal activity.

Chemical Properties

Off-white, yellowish powder or dark brown emulsifiable concentrate.

Uses

Azadirachtin is a tetranortriterpinoid isolated from the seeds of the neem tree. Highly active insect feeding deterrent and growth regulator.It is used experimentally as insect control agent.

Uses

Azadiractin is extracted from the neem tree (Azadirachta indica). It is the principal active ingredient of extracts of neem. Neem extracts and pure azadirachtin are used to control whitefly, leaf miners and other pests including pear psylla.

Definition

ChEBI: A member of the family of azadirachtins that is isolated from the neem tree (Azadirachta indica).

Agricultural Uses

Insecticides, Nematicide: Azadirachtin is an extract of fruit from the Neem tree, which is largely grown in India. It is used as a commercial insect growth regulator that controls the metamorphosis process as the insect passes from the larva stage to the pupa stage. The Neem tree also yields extracts from its bark, leaves and wood that are used in medicine and cosmetics.

Trade name

ALIGN®; AZATIN EC®; AZATIN®-XL PLUS; AZATROL EC®; AMAZIN® ECOZIN® EI- 783®; MARGOSAN-O®; NEEM®; NEEMAZAL®; ORNAZIN® SALANNIN®; SUPERNEEM®; TURPLEX®

Biochem/physiol Actions

Triterpenoid found in need tree seeds, azadiractin suppresses feeding by many insect species and disrupts growth of most insect and other arthropod species, while having very low mammalian toxicity. Promising as a natural pesticide.

Potential Exposure

Biological tetranortriterpinoid insecticide; insect growth regulator. A natural product extracted from seeds of the Neem tree (Azadirachta indica).

Metabolic pathway

The natural insecticide azadirachtin is most stable in mildly acidic solutions between pH 4 and 6 at room temperature and unstable in alkaline and strong acidic conditions. While azadirachtin is relatively stable to heating in the seeds or as a pure solid, it is rapidly destroyed or altered by heating in aqueous solution and methanol. In methanol at 90°C, it is quantitatively converted to 3-acetyl-1-tigloylazadirachtinin.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Degradation

After 90 hours exposure to UV radiation, very little azadirachtin (l)its 3- acetyl derivative and 22,23-dihydroazadirachtin remained intact. However, these compounds retained biological activity, and at least 200 hours irradiation was necessary to reduce the biological activity of 1. It is suggested that the effect of ultraviolet radiation is confined to the tigloyl residue which is common to these three compounds and which may undergo cis-trans isomerisation, rearrangement, etc. without significant effect on the biological activity of the molecule, because reduction or removal of the tigloyl residue causes only limited reduction in biological activity of the parent (Barnby ef al., 1989).
Azadirachtin was hydrolysed readily in several buffers (pH 4.1-8.1) and natural waters (pH 6.2,7.3,8.0 and 8.1) at 35 °C and its disappearance followed pseudo-first-order kinetics (Szeto and Wan, 1996). Rates of disappearance of the parent were faster in basic than in acidic solution (DT₅₀ was 12 hours at pH 8 and 206 hours at pH 6) and the compound is not expected to be persistent in water.

Mode of action

Azadirachtin acts on insect gustatory receptors to inhibit feeding, and also interferes with development by inhibiting synthesis of the neuropeptide that triggers ecdysone release. The molecular targets mediating these effects are not known.

Toxicity evaluation

Azadirachtin is practically non-toxic to mammals, birds and plants. It is moderately toxic to aquatic invertebrates, but exposure is negligible due to low application rates and rapid degradation. Since it is only active by ingestion of treated foliage, exposure of non-target insects and honeybees is minimal.

Incompatibilities

Powder or liquid may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, reducing agents and metals, acid chlorides, alkalis, alkali metals, high heat, including sunlight.

Waste Disposal

Waste product may be disposed of onsite (open dumping may be prohibited) or at an approved waste disposal facility. All federal, state, and local environmental regulations must be observed.

Azadirachtin Preparation Products And Raw materials

Raw materials

Preparation Products

Azadirachtin Suppliers

Global Suppliers ( 244)

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu Biopurify Phytochemicals Ltd.	+86-028-82633397 18982077548	cwb1@biopurify.cn	China	2376	60
Henan Yanyuan Biotechnology Co., Ltd	18637186683	2392060329@qq.com	China	36	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29977	65
TargetMol Chemicals Inc.	021-021-33632979 15002134094	marketing@targetmol.com	China	7993	58
TianJin Alta Scientific Co., Ltd.	022-65378550-8551	contact@altascientific.com	China	2772	58
Chengdu HuaXia Chemical Reagent Co. Ltd	400-1166-196 13458535857	cdhxsj@163.com	China	13323	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
Finetech Industry Limited	027-87465837 19945049750	sales@finetechnology-ind.com	China	9331	58

Supplier	Advantage
Chengdu Biopurify Phytochemicals Ltd.	60
Henan Yanyuan Biotechnology Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Chemsky (shanghai) International Co.,Ltd	60
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
TargetMol Chemicals Inc.	58
TianJin Alta Scientific Co., Ltd.	58
Chengdu HuaXia Chemical Reagent Co. Ltd	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Finetech Industry Limited	58

View Latest Price from Azadirachtin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-17	AZADIRACHTIN A 11141-17-6			0.99		RongNa Biotechnology Co.,Ltd
2026-07-27	Azadirachtin 11141-17-6	$58.00-347.00		99.71%	10g	TargetMol Chemicals Inc.
2026-05-22	Azadirachtin 11141-17-6		1kg	99%	1000 kg	BINBOBIO CO., LTD.

AZADIRACHTIN A
11141-17-6
0.99
RongNa Biotechnology Co.,Ltd

Azadirachtin
11141-17-6
$58.00-347.00
99.71%
TargetMol Chemicals Inc.

Azadirachtin
11141-17-6
$0.00
99%
BINBOBIO CO., LTD.

Azadirachtin Spectrum

Azadirachtin(11141-17-6)¹HNMR

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AZATIN AZATIN(R) KAYNEEM 3-TIGLOYL-AZADIRACHTOL AZADIRACHTIN, 10MG, NEAT 1H,7H-Naphtho1,8-bc:4,4a-cdifuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-(2E)-2-methyl-1-oxo-2-butenyloxy-4-(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro2,3-boxirenoeoxepin-1a(2H) AZADIRACHTIN pure PHEROTECH Azadirachtin 10mg [11141-17-6] Azaditrachtin Nsc368675 AZADIRACHTIN A(P) Azadirachtin Solution, 100ppm NEEMOLIN NEEMAZAD NEEMAZAL NEEMIX AZAD AZADIRACCHTIN A AZADIRACHTIN (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-(Acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-1H,7H-naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylic acid 5,10a-dimethyl ester Azatin EC Azatin Magnum Azatin XL Ecozin Gronim NeemAzal F NeemAzal T NeemAzal W Neemazol Neemgold Nimbicidine Nimurin Oikos Oikos 25 plus Oikos 323 Bio Ornazin Safer BioNEEM Suneem Superneem (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-(Acetyloxy)octahydro-3,5-dihydroxy-4-Methyl-8-[[(2E)-2-Methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-Methyl-2,7-Methanofuro[2,3-b]oxireno[e]oxepin-1a(2 1H,7H-Naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylicacid,10-(acetyloxy)octahydro-3,5-dihydroxy-4-Methyl-8-[[(2E)-2-Methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-Methyl-2,7-Methanofuro[2,3-b]oxireno[e] Azadirachtin(Technical) Azadirachtin @100 μg/mL in Methanol 1H,7H-Naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-, 5,10a-dimethyl ester, (... Azadirachtin 100 μg/mL in Acetonitrile Cypermethrin Impurity 8 Azadirachtin in Methanol Azadirachtin A 100 μg/ml Acetonitrile Azadirachtin-RM Azadirachtin, 10 mM in DMSO Neem Leaves Powder Azadirachtin Derivative (Natural Deworming) 1H,7H-Naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylicacid,10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-,5,10a-dimethyl ester, (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)- AZADIRACHTIN B AZADIRACTIN AZADIRACHTIN A Azadirachtin-A / Neem oil