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3-Methoxythiophene

CAS No.
17573-92-1
Chemical Name:
3-Methoxythiophene
Synonyms
EA004;Compound Fr14554;3-METHOXYTHIOPHENE;m-Methoxythiophene;Methoxythiophene,95%;Thiophene, 3-methoxy-;3-Methoxythiophene>METHYL 3-THIENYL ETHER;3-Methoxythiophene,98%;3-Methoxythiophene,99%
CBNumber:
CB1312405
Molecular Formula:
C5H6OS
Molecular Weight:
114.17
MDL Number:
MFCD00043894
MOL File:
17573-92-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:31:31

3-Methoxythiophene Properties

Melting point 49-50 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4))
Boiling point 80-82 °C/65 mmHg (lit.)
Density 1.143 g/mL at 25 °C (lit.)
refractive index n20/D 1.532(lit.)
Flash point 121 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
form Liquid
color Clear light brown
Sensitive Air Sensitive
BRN 106404
InChI InChI=1S/C5H6OS/c1-6-5-2-3-7-4-5/h2-4H,1H3
InChIKey RFSKGCVUDQRZSD-UHFFFAOYSA-N
SMILES C1SC=CC=1OC
LogP 1.810 (est)
CAS DataBase Reference 17573-92-1(CAS DataBase Reference)
NIST Chemistry Reference Thiophene, 3-methoxy-(17573-92-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Warning
Hazard statements  H226
Precautionary statements  P210-P233-P240-P241-P242-P243
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Risk Statements  10
Safety Statements  16-27-36/37/39
RIDADR  UN 1993 3/PG 3
WGK Germany  3
13
HazardClass  3
PackingGroup  III
HS Code  29339900
Storage Class 3 - Flammable liquids
Hazard Classifications Flam. Liq. 3
REACH Registrations Inactive
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
0 0

3-Methoxythiophene price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 374024 3-Methoxythiophene 98% 17573-92-1 5g $141 2026-04-30 Buy
TCI Chemical M1093 3-Methoxythiophene >98.0%(GC) 17573-92-1 1g $30 2026-04-30 Buy
TCI Chemical M1093 3-Methoxythiophene >98.0%(GC) 17573-92-1 5g $57 2026-04-30 Buy
AstaTech 63554 3-METHOXYTHIOPHENE 95% 17573-92-1 5G $10 2026-04-30 Buy
AstaTech 63554 3-METHOXYTHIOPHENE 95% 17573-92-1 25G $21 2026-04-30 Buy
Product number Packaging Price Buy
374024 5g $141 Buy
M1093 1g $30 Buy
M1093 5g $57 Buy
63554 5G $10 Buy
63554 25G $21 Buy

3-Methoxythiophene Chemical Properties, Uses, Production

Chemical Properties

Clear light brown liquid

Uses

3-Methoxythiophene, is a heterocyclic building block used for the synthesis of more complex compounds containing Thiophene moiety. It can also be used for the preparation of novel thiophenyl-methylene-9H-fluorene-based low bandgap polymers.

Synthesis Reference(s)

Synthetic Communications, 20, p. 213, 1990 DOI: 10.1080/00397919008052285

General Description

3-Methoxythiophene is a thiophene. The intramolecular and intermolecular geometries of crystals of 3-methoxythiophene were studied. Spectroscopic studies of bipolarons derived from oligomerized 3-methoxythiophene in solution has been reported. The electropolymerization of 3-methoxythiophene on Pt and Fe electrodes in an aqueous micellar medium containing sodium dodecyl sulfate and 10-3M bithiophene has been reported. Thin polymer films of 3-methoxythiophene at the cathode in a direct current discharge have been prepared.

Materials Uses

Thin polymer films were obtained from 3-methoxythiophene at the cathode in a dc discharge.

Synthesis

3-Bromothiophene

872-31-1

Sodium Methoxide

124-41-4

3-Methoxythiophene

17573-92-1

Example 2 Preparation of 3-methoxythiophene: 185 g of 3-bromothiophene (1.13 mol), 3.24 g of copper(I) bromide (CuBr, 2 mol%) and 14.1 g of PEG DME 250 (5 mol%) were added to the reactor. Subsequently, sodium methanol solution (30% concentration, precursor concentration 30.4) was added and the mixture was heated to 90 °C. The conversion was monitored by GC during the reaction and was >98% (reaction time totaled 10 hours). Upon completion of the reaction, the mixture was poured into 300 g of water. After filtration through decalite, the mixture was extracted twice with 120 g of methyl tertiary butyl ether (MTBE). The organic phases were combined and subjected to vacuum fractionation to afford 117.4 g of 3-methoxythiophene (1.03 mol, 91% yield) with a GC purity of >99% (% area).

References

[1] Patent: US2008/71084, 2008, A1. Location in patent: Page/Page column 4
[2] Polymer, 2013, vol. 54, # 18, p. 4930 - 4939
[3] Journal of Materials Chemistry C, 2015, vol. 3, # 7, p. 1595 - 1603
[4] Chemical Communications, 2013, vol. 49, # 49, p. 5538 - 5540
[5] Research on Chemical Intermediates, 2015, vol. 41, # 11, p. 8651 - 8664

872-31-1
124-41-4
17573-92-1
Synthesis of 3-Methoxythiophene from 3-Bromothiophene and Sodium Methoxide

3-Methoxythiophene Preparation Products And Raw materials

Global Suppliers ( 288)
Supplier Tel Email Country ProdList Advantage
Aikon International Limited 17714375163 hywu@aikonchem.com China 9974 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Beijing Donghualituo Techonlogy Development Co.,Ltd. 010-88425576 sales@dhltchem.com China 793 59
New Energy Chemicals 0515-82159099 13770142076 info@njuchem.com China 251 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60

View Latest Price from 3-Methoxythiophene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Methoxythiophene pictures 2026-09-02 3-Methoxythiophene
17573-92-1
$1.00-200.00 1KG 99%, 99.5% Sublimated Henan Fengda Chemical Co., Ltd
3-Methoxythiophene  pictures 2026-08-20 3-Methoxythiophene
17573-92-1
$1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
3-Methoxythiophene pictures 2026-03-20 3-Methoxythiophene
17573-92-1
$10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
  • 3-Methoxythiophene pictures
  • 3-Methoxythiophene
    17573-92-1
  • $1.00-200.00
  • 99%, 99.5% Sublimated
  • Henan Fengda Chemical Co., Ltd
3-Methoxythiophene,98% m-Methoxythiophene 3-Methoxythiophene, 98% 5GR 3-Methoxythiophene,99% 3-METHOXYTHIOPHENE METHYL 3-THIENYL ETHER Methoxythiophene,95% 3-Methoxythiophene> Thiophene, 3-methoxy- 3-Methoxythiophene ISO 9001:2015 REACH EA004 Compound Fr14554 17573-92-1 16848-22-6 Heterocyclic Building Blocks Thiophenes Building Blocks Reagents for Conducting Polymer Research Thiophene Derivatives (for Conduting Polymer Research) Functional Materials Reagents for Conducting Polymer Research Thiophene Derivatives (for Conduting Polymer Research) Thiophen Building Blocks Heterocyclic Building Blocks Thiophene&Benzothiophene Thiophens Thiophene Series Pyridines ,Halogenated Heterocycles Sulphur Derivatives Thiophenes