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ChemicalBook >> CAS DataBase List >>Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Structure
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate structure
CAS No.
1690176-75-0
Chemical Name:
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate
Synonyms
IUN76750;PAR-2-IN-1;PAR-2 inhibitor;PAR-2-IN intermediate-1;PAR-2-IN-1, 10 mM in DMSO;Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-car;Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate;Imidazo[1,2-b]pyridazine-2-carboxylic acid, 6-chloro-8-(1,1-dimethylethyl)-, methyl ester;Inhibitor,PAR2IN1,anti-inflammatory,anticancer,PAR 2 IN 1,inhibit,PAR2,Thrombin receptors,Protease Activated Receptor (PAR)
CBNumber:
CB13162104
Molecular Formula:
C12H14ClN3O2
Molecular Weight:
267.71
MDL Number:
MFCD28144723
MOL File:
1690176-75-0.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Properties

Density 1.31±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO : 83.33 mg/mL (311.27 mM; Need ultrasonic)
pka 0.85±0.30(Predicted)
form Solid
color White to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0149418 PAR-2-IN intermediate-1 ≥98% 1690176-75-0 100mg $88 2026-06-04 Buy
ChemScene CS-0149418 PAR-2-IN intermediate-1 ≥98% 1690176-75-0 250mg $127 2026-06-04 Buy
ChemScene CS-0149418 PAR-2-IN intermediate-1 ≥98% 1690176-75-0 1g $390 2026-06-04 Buy
Matrix Scientific 307159 Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate 1690176-75-0 100.00mg $104 2026-05-19 Buy
Matrix Scientific 307159 Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate 1690176-75-0 250.00mg $152 2026-05-19 Buy
Product number Packaging Price Buy
CS-0149418 100mg $88 Buy
CS-0149418 250mg $127 Buy
CS-0149418 1g $390 Buy
307159 100.00mg $104 Buy
307159 250.00mg $152 Buy

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Chemical Properties, Uses, Production

Uses

PAR-2-IN-1 is a protease-activated receptor-2 (PAR2) signaling pathway inhibitor with anti-inflammatory and anticancer effects[1].

IC 50

PAR2

References

[1] Luc J. Farmer, et al. Imidazopyridazines useful as inhibitors of the par-2 signaling pathway. WO2015048245A1.

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Suppliers

Global Suppliers ( 44)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2969 58
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 400821072 malulu@leyan.com China 24933 58
Alichem(Changzhou) Co., Ltd. 19941333411 sales@alichem.cn China 523 58
Suzhou Rovathin Foreign Trade Co.,Ltd 0512-65816829 18662214788 info@rovathin.com.cn China 9962 58
Supplier Advantage
BOC Sciences 65
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Shanghai Rechem science Co., Ltd. 58
Shanghai SuperLan Chemcial Technique Centre 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Alichem(Changzhou) Co., Ltd. 58
Suzhou Rovathin Foreign Trade Co.,Ltd 58

View Latest Price from Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PAR-2-IN-1 pictures 2026-07-27 PAR-2-IN-1
1690176-75-0
 $30.00-103.00 99.79% 10g TargetMol Chemicals Inc.
  • PAR-2-IN-1 pictures
  • PAR-2-IN-1
    1690176-75-0
  • $30.00-103.00
  • 99.79%
  • TargetMol Chemicals Inc.

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Spectrum

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate(1690176-75-0)1HNMR

1690176-75-0 (Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate) Related Search:

6-Chloro-imidazo[1,2-b]pyridazine-2-carboxylic acid, methyl ester Ethyl 6-chloroimidazo[1,2-b]pyridazine-2-carboxylate 6-Chloroimidazo[1,2-b]pyridazine-2-carboxylic acid Imidazo[1,2-b]pyridazine-2-carboxylic acid, 6-chloro-8-(1-methylethyl)-, methyl ester Imidazo[1,2-b]pyridazine-3-carboxylic acid, 6-chloro-8-methyl-, ethyl ester
Imidazo[1,2-b]pyridazine-3-carboxylic acid, 6-chloro-8-methyl-

1of2

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Imidazo[1,2-b]pyridazine-2-carboxylic acid, 6-chloro-8-(1,1-dimethylethyl)-, methyl ester IUN76750 PAR-2-IN-1 PAR-2 inhibitor Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-car Inhibitor,PAR2IN1,anti-inflammatory,anticancer,PAR 2 IN 1,inhibit,PAR2,Thrombin receptors,Protease Activated Receptor (PAR) PAR-2-IN-1, 10 mM in DMSO PAR-2-IN intermediate-1 1690176-75-0