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ChemicalBook >> CAS DataBase List >>Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Structure
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate structure
CAS No.
1690176-75-0
Chemical Name:
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate
Synonyms
IUN76750;PAR-2-IN-1;PAR-2 inhibitor;PAR-2-IN-1, 10 mM in DMSO;Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-car;Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate;Imidazo[1,2-b]pyridazine-2-carboxylic acid, 6-chloro-8-(1,1-dimethylethyl)-, methyl ester;Inhibitor,PAR2IN1,anti-inflammatory,anticancer,PAR 2 IN 1,inhibit,PAR2,Thrombin receptors,Protease Activated Receptor (PAR)
CBNumber:
CB13162104
Molecular Formula:
C12H14ClN3O2
Molecular Weight:
267.71
MDL Number:
MFCD28144723
MOL File:
1690176-75-0.mol
Last updated:2025-09-22 14:50:28
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Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Properties

Density 1.31±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO : 83.33 mg/mL (311.27 mM; Need ultrasonic)
pka 0.85±0.30(Predicted)
form Solid
color White to light yellow

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0149418 PAR-2-IN-1 99.16% 1690176-75-0 10mg $170 2021-12-16 Buy
AK Scientific 2164EF Methyl8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate 1690176-75-0 250mg $282 2021-12-16 Buy
ChemScene CS-0149418 PAR-2-IN-1 99.16% 1690176-75-0 25mg $350 2021-12-16 Buy
ChemScene CS-0149418 PAR-2-IN-1 99.16% 1690176-75-0 5mg $100 2021-12-16 Buy
ChemScene CS-0149418 PAR-2-IN-1 99.16% 1690176-75-0 50mg $550 2021-12-16 Buy
Product number Packaging Price Buy
CS-0149418 10mg $170 Buy
2164EF 250mg $282 Buy
CS-0149418 25mg $350 Buy
CS-0149418 5mg $100 Buy
CS-0149418 50mg $550 Buy

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Chemical Properties,Uses,Production

Uses

PAR-2-IN-1 is a protease-activated receptor-2 (PAR2) signaling pathway inhibitor with anti-inflammatory and anticancer effects[1].

IC 50

PAR2

References

[1] Luc J. Farmer, et al. Imidazopyridazines useful as inhibitors of the par-2 signaling pathway. WO2015048245A1.

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		+8613288715578 sales@sichuanzyyt.com China 12248 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39031 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859 Intermediate@cato-chem.com China 3861 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3504 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4669 55
Shanghai Send Pharmaceutical Technology Co., Ltd. 021-58088081 Q2816483246 hailey@shsendpharm.com China 2637 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Guangzhou CATO Research Chemicals Inc. 		58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai Send Pharmaceutical Technology Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60

View Lastest Price from Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PAR-2-IN-1 pictures 2025-09-22 PAR-2-IN-1
1690176-75-0
 US $48.00-173.00 / mg 99.79% 10g TargetMol Chemicals Inc.
  • PAR-2-IN-1 pictures
  • PAR-2-IN-1
    1690176-75-0
  • US $48.00-173.00 / mg
  • 99.79%
  • TargetMol Chemicals Inc.

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Spectrum

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate(1690176-75-0)1HNMR
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Imidazo[1,2-b]pyridazine-2-carboxylic acid, 6-chloro-8-(1,1-dimethylethyl)-, methyl ester IUN76750 PAR-2-IN-1 PAR-2 inhibitor Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-car Inhibitor,PAR2IN1,anti-inflammatory,anticancer,PAR 2 IN 1,inhibit,PAR2,Thrombin receptors,Protease Activated Receptor (PAR) PAR-2-IN-1, 10 mM in DMSO 1690176-75-0