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C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE

CAS No.
120740-10-5
Chemical Name:
C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
Synonyms
5-Aminomethyl-2-Bromopyridine;6-Bromo-3-pyridinemethanamine;(6-bromo-3-pyridyl)methanamine;3-Pyridinemethanamine, 6-bromo-;(6-broMopyridin-3-yl)MethanaMine;(2-Bromo-5-pyridinyl)methylamine;C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE;5-(Aminomethyl)-2-bromopyridine 95+%;C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE ISO 9001:2015 REACH
CBNumber:
CB1317536
Molecular Formula:
C6H7BrN2
Molecular Weight:
187.04
MDL Number:
MFCD06738744
MOL File:
120740-10-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:44
Product description Number Pack Size Price
5-Aminomethyl-2-bromopyridine A613685 250mg $95
5-(Aminomethyl)-2-bromopyridine 98% 3H30-9-0A 250mg $74
5-(Aminomethyl)-2-bromopyridine OR345226 250mg $88
5-(Aminomethyl)-2-bromopyridine 98% A10387 1g $90
5-(Aminomethyl)-2-bromopyridine 98% 3H30-9-0A 1g $320

C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE Properties

Boiling point 290.1±25.0 °C(Predicted)
Density 1.574±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form solid
pka 7.74±0.29(Predicted)
color Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P280-P301+P312-P362+P364
HS Code  2933399990

C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A613685 5-Aminomethyl-2-bromopyridine 120740-10-5 250mg $95 2021-12-16 Buy
SynQuest Laboratories 3H30-9-0A 5-(Aminomethyl)-2-bromopyridine 98% 120740-10-5 250mg $74 2021-12-16 Buy
Apolloscientific OR345226 5-(Aminomethyl)-2-bromopyridine 120740-10-5 250mg $88 2021-12-16 Buy
Frontier Specialty Chemicals A10387 5-(Aminomethyl)-2-bromopyridine 98% 120740-10-5 1g $90 2021-12-16 Buy
SynQuest Laboratories 3H30-9-0A 5-(Aminomethyl)-2-bromopyridine 98% 120740-10-5 1g $320 2021-12-16 Buy
Product number Packaging Price Buy
A613685 250mg $95 Buy
3H30-9-0A 250mg $74 Buy
OR345226 250mg $88 Buy
A10387 1g $90 Buy
3H30-9-0A 1g $320 Buy

C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE Chemical Properties,Uses,Production

Synthesis

Pyridine, 2-bromo-5-(bromomethyl)- (9CI)

101990-45-8

C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE

120740-10-5

General procedure for the synthesis of 5-aminomethyl-2-bromopyridine from 2-bromo-5-(bromomethyl)pyridine: 2-bromo-5-methylpyridine (70.0 mmol) and N-bromosuccinimide (80.0 mmol) were dissolved in 1,2-dichloroethane (150 mL), followed by addition of 2,2'-azino-bis(2-methylpropionitrile) (1.50 mmol). The reaction mixture was heated at reflux for 15 minutes at 85 °C, another portion of 2,2'-azobis(2-methylpropionitrile) (1.50 mmol) was added and heating was continued at 85 °C for 15 minutes. After completion of the reaction, it was cooled to room temperature and the reaction mixture was allowed to stand at 5 °C for 2 h. The precipitate was collected by filtration and washed with a small amount of 1,2-dichloroethane. The filtrate was concentrated under reduced pressure and the resulting crude product was used directly in the next step of the reaction. The crude 2-bromo-5-(bromomethyl)pyridine was dissolved in chloroform (100 mL) and urotropine (70.0 mmol) was added. The reaction mixture was stirred at room temperature for 16 h. The precipitate was collected by filtration, washed with a little chloroform and dried in air. The resulting urotropin salt was mixed with concentrated hydrochloric acid and refluxed for 90 minutes, cooled to room temperature and then a mixture of 40% aqueous formaldehyde (5.0 mL) and ammonium hydroxide (12 mL) and water (80 mL) was added under stirring. The precipitate was collected by filtration, washed with ice water and dried in a vacuum desiccator. The crude product was purified by recrystallization from ethanol. Yield: 40%, melting point: 105-106 °C. Elemental analysis: calculated value of C5H7BrN2 (187.04): C, 38.53; H, 3.77; N, 14.98. measured value: C, 38.22; H, 3.72; N, 14.71. hplc-MS (ESI+): m/z 188.02 (97.2%). 1H NMR (DMSO-d6): δ 4.04 (t. J=5.67 Hz, 2H, CH2), 7.71 (d, J=8.19 Hz, 1H, ArH), 7.95 (dd, J=8.19, J'=1.95 Hz, 1H, ArH), 8.51 (d, J=1.95 Hz, 1H, ArH), 8.74 (s, br, 2H, NH2).

References

[1] Patent: US2015/368248, 2015, A1. Location in patent: Paragraph 0089
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 15, p. 6234 - 6247

C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE Preparation Products And Raw materials

C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE Suppliers

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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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Suzhou ARTK Medchem Co., Ltd.
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View Lastest Price from C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE pictures 2025-11-18 C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
120740-10-5
US $1.10 / g 1g 99.00% 100 Tons min Dideu Industries Group Limited
5-AminoMethyl-2-Bromopyridine pictures 2020-05-13 5-AminoMethyl-2-Bromopyridine
120740-10-5
US $0.00-0.00 / Kg 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE pictures 2019-12-26 C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
120740-10-5
US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co

C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE Spectrum

C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE 5-Aminomethyl-2-Bromopyridine (2-Bromo-5-pyridinyl)methylamine (6-broMopyridin-3-yl)MethanaMine 3-Pyridinemethanamine, 6-bromo- 5-(Aminomethyl)-2-bromopyridine 95+% (6-bromo-3-pyridyl)methanamine C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE ISO 9001:2015 REACH 6-Bromo-3-pyridinemethanamine 120740-10-5 12074-10-5 Building Blocks Pyridine