C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
- CAS No.
- 120740-10-5
- Chemical Name:
- C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
- Synonyms
- 5-Aminomethyl-2-Bromopyridine;6-Bromo-3-pyridinemethanamine;(6-bromo-3-pyridyl)methanamine;3-Pyridinemethanamine, 6-bromo-;(6-broMopyridin-3-yl)MethanaMine;(2-Bromo-5-pyridinyl)methylamine;C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE;5-(Aminomethyl)-2-bromopyridine 95+%;C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE ISO 9001：2015 REACH
- CBNumber:
- CB1317536
- Molecular Formula:
- C6H7BrN2
- Molecular Weight:
- 187.04
- MDL Number:
- MFCD06738744
- MOL File:
- 120740-10-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P301+P312-P362+P364 |
| HS Code | 2933399990 |
C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-A613685-500MG | 5-Aminomethyl-2-bromopyridine | 120740-10-5 | 500mg | $205 | 2026-06-03 | Buy |
| TRC | TRC-A613685-250MG | 5-Aminomethyl-2-bromopyridine | 120740-10-5 | 250mg | $135 | 2026-06-03 | Buy |
| TRC | TRC-A613685-100MG | 5-Aminomethyl-2-bromopyridine | 120740-10-5 | 100mg | $70 | 2026-06-03 | Buy |
| Activate Scientific | AS31580 | (6-Bromopyridin-3-yl)methylamine 95% | 120740-10-5 | 1g | $72 | 2026-06-04 | Buy |
| Activate Scientific | AS31580 | (6-Bromopyridin-3-yl)methylamine 95% | 120740-10-5 | 5g | $314 | 2026-06-04 | Buy |
C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE Chemical Properties,Uses,Production
Synthesis
101990-45-8
120740-10-5
General procedure for the synthesis of 5-aminomethyl-2-bromopyridine from 2-bromo-5-(bromomethyl)pyridine: 2-bromo-5-methylpyridine (70.0 mmol) and N-bromosuccinimide (80.0 mmol) were dissolved in 1,2-dichloroethane (150 mL), followed by addition of 2,2'-azino-bis(2-methylpropionitrile) (1.50 mmol). The reaction mixture was heated at reflux for 15 minutes at 85 °C, another portion of 2,2'-azobis(2-methylpropionitrile) (1.50 mmol) was added and heating was continued at 85 °C for 15 minutes. After completion of the reaction, it was cooled to room temperature and the reaction mixture was allowed to stand at 5 °C for 2 h. The precipitate was collected by filtration and washed with a small amount of 1,2-dichloroethane. The filtrate was concentrated under reduced pressure and the resulting crude product was used directly in the next step of the reaction. The crude 2-bromo-5-(bromomethyl)pyridine was dissolved in chloroform (100 mL) and urotropine (70.0 mmol) was added. The reaction mixture was stirred at room temperature for 16 h. The precipitate was collected by filtration, washed with a little chloroform and dried in air. The resulting urotropin salt was mixed with concentrated hydrochloric acid and refluxed for 90 minutes, cooled to room temperature and then a mixture of 40% aqueous formaldehyde (5.0 mL) and ammonium hydroxide (12 mL) and water (80 mL) was added under stirring. The precipitate was collected by filtration, washed with ice water and dried in a vacuum desiccator. The crude product was purified by recrystallization from ethanol. Yield: 40%, melting point: 105-106 °C. Elemental analysis: calculated value of C5H7BrN2 (187.04): C, 38.53; H, 3.77; N, 14.98. measured value: C, 38.22; H, 3.72; N, 14.71. hplc-MS (ESI+): m/z 188.02 (97.2%). 1H NMR (DMSO-d6): δ 4.04 (t. J=5.67 Hz, 2H, CH2), 7.71 (d, J=8.19 Hz, 1H, ArH), 7.95 (dd, J=8.19, J'=1.95 Hz, 1H, ArH), 8.51 (d, J=1.95 Hz, 1H, ArH), 8.74 (s, br, 2H, NH2).
References
[1] Patent: US2015/368248, 2015, A1. Location in patent: Paragraph 0089
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 15, p. 6234 - 6247
C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 984 | 62 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
View Lastest Price from C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
120740-10-5
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-13 | 5-AminoMethyl-2-Bromopyridine
120740-10-5
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-12-26 | C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
120740-10-5
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
120740-10-5
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-AminoMethyl-2-Bromopyridine
120740-10-5
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
120740-10-5
- $1.00
- 99%
- Career Henan Chemical Co
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