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4-(Dimethylamino)phenyldiphenylphosphine

4-(Dimethylamino)phenyldiphenylphosphine Structure
4-(Dimethylamino)phenyldiphenylphosphine structure
CAS No.
739-58-2
Chemical Name:
4-(Dimethylamino)phenyldiphenylphosphine
Synonyms
TricyclohexylphosphoniuM;4-(Diphenylphosphanyl)-N,N-dimethylaniline;4-(DIMETHYLAMINO)TRIPHENYLPHOSPHINE;4-(Diphenylphosphanyl)-N,N-dimethylanil;(Diphenylphosphino)-N,N-dimethylaniline;4-(Dimethylamino)phenyldiphenylphosphine;4-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLANILINE;4-(Dimethylamino)phenyldiphenylphosphine>4-(Dimethylamino)phenyldiphenylphosphine 95%;4-(tetramethylamine) phenyldiphenylphosphine
CBNumber:
CB1333837
Molecular Formula:
C20H20NP
Molecular Weight:
305.35
MDL Number:
MFCD00192068
MOL File:
739-58-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:49:12
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4-(Dimethylamino)phenyldiphenylphosphine Properties

Melting point 151-154 °C (lit.)
Boiling point 417.5±28.0 °C(Predicted)
storage temp. Inert atmosphere,Room Temperature
form solid
pka 4.20±0.12(Predicted)
color white
Sensitive air sensitive
BRN 916331
InChI 1S/C20H20NP/c1-21(2)17-13-15-20(16-14-17)22(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-16H,1-2H3
InChIKey GOEGBJDTWXTPHP-UHFFFAOYSA-N
SMILES CN(C)c1ccc(cc1)P(c2ccccc2)c3ccccc3
CAS DataBase Reference 739-58-2
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
TSCA  No
HS Code  29319090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

4-(Dimethylamino)phenyldiphenylphosphine price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 395021 4-(Dimethylamino)phenyldiphenylphosphine 95% 739-58-2 5g $222 2026-04-30 Buy
TCI Chemical D2478 4-(Dimethylamino)phenyldiphenylphosphine >95.0%(GC) 739-58-2 1g $51 2026-04-30 Buy
TCI Chemical D2478 4-(Dimethylamino)phenyldiphenylphosphine >95.0%(GC) 739-58-2 5g $141 2026-04-30 Buy
Strem Chemicals 15-1380 Diphenyl[4-(N,N-dimethylamino)phenyl]phosphine, min. 95% min.95% 739-58-2 1g $49 2026-04-30 Buy
Strem Chemicals 15-1380 Diphenyl[4-(N,N-dimethylamino)phenyl]phosphine, min. 95% min.95% 739-58-2 5g $191 2026-04-30 Buy
Product number Packaging Price Buy
395021 5g $222 Buy
D2478 1g $51 Buy
D2478 5g $141 Buy
15-1380 1g $49 Buy
15-1380 5g $191 Buy

4-(Dimethylamino)phenyldiphenylphosphine Chemical Properties, Uses, Production

Uses

Catalyst for:

  • Preparation of dicyano(aryl)cyclohexenecarboxylic acid esters via regioselective annulation
  • Diastereoselective cycloaddition of styrenyl allenoates
  • Interfacial carbonylation of methylbenzyl bromide
  • Hydroformylation of octene

Reducing agent for selectivity of disulfide-internally linked peptide-nucleic acid cleavage

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

Synthesis

4-Bromo-N,N-dimethylaniline

586-77-6

Chlorodiphenylphosphine

1079-66-9

4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE

739-58-2

Grignard reagent was prepared by adding 50 g of 4-bromo-N,N-dimethylaniline, 7 g of magnesium shavings, and 400 mL of anhydrous tetrahydrofuran (THF) to a 1 L three-necked flask under nitrogen protection, and the reaction was carried out at reflux for 10 hours. After the reaction was completed, it was cooled to room temperature, 2.9 g of tetrakis(triphenylphosphine)palladium was added and stirred for 3 hours. Subsequently, 61 g of diphenylphosphonium chloride was slowly added dropwise at room temperature, and after completion of the dropwise addition, the reaction mixture was refluxed for 8 hours. At the end of the reaction, the mixture was slowly added dropwise to 200 mL of reaction solution under cooling in an ice water bath. The reaction was quenched with saturated aqueous ammonium chloride solution and the organic phase was separated. The organic phase was crystallized by addition of methanol and filtered to give 74 g of white solid 4-(N,N-dimethylamino)triphenylphosphine in 96% yield.

References

[1] Patent: CN105859774, 2016, A. Location in patent: Paragraph 0090; 0091; 0092; 0093
[2] Journal of Organometallic Chemistry, 1999, vol. 575, # 1, p. 63 - 66
[3] Russian Journal of General Chemistry, 2000, vol. 70, # 4, p. 524 - 528
[4] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1974, p. 37 - 41
[5] Chemische Berichte, 1984, vol. 117, # 9, p. 2791 - 2802

4-(Dimethylamino)phenyldiphenylphosphine Preparation Products And Raw materials

Raw materials

Nitrogen Calcium oxide Chloroform Aluminum chloride Chlorodiphenylphosphine
N,N-Dimethylaniline Benzene Hydrochloric acid Sodium hydroxide Pyridine

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Preparation Products

4-(Dimethylamino)phenyldiphenylphosphine Suppliers

Global Suppliers ( 193)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Puyang Huicheng Electronic Material Co. Ltd. 0393-0393-8910800 15039333257 info@huichengchem.com China 588 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Puyang Huicheng Electronic Material Co. Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64

View Latest Price from 4-(Dimethylamino)phenyldiphenylphosphine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(DiMethylaMino)phenyldiphenylphosphine pictures 2026-08-07 4-(DiMethylaMino)phenyldiphenylphosphine
739-58-2
 $1.00 1KG 99% 20 tons Shaanxi Dideu Medichem Co. Ltd
4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE pictures 2026-06-30 4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE
739-58-2
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-(Diphenylphosphino)-N,N-dimethylaniline pictures 2025-12-23 4-(Diphenylphosphino)-N,N-dimethylaniline
739-58-2
 1kg 98% 2T XINXIANG RUNYU MATERIAL CO., LTD.

4-(Dimethylamino)phenyldiphenylphosphine Spectrum

4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE(739-58-2)1HNMR4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE(739-58-2)31PNMR4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE(739-58-2)13CNMR4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE(739-58-2)Raman4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE(739-58-2)IR

739-58-2 (4-(Dimethylamino)phenyldiphenylphosphine) Related Search:

Chloro(triphenylphosphine)gold Solphos SL-A001-1 Tris(4-dimethylaminophenyl)phosphine N1,N1-Dimethyl-4-(di[4-(dimethylamino)phenyl]phosphoryl)aniline (S)-7,7'-Bis[bis(3,5-dimethylphenyl)phosphino]-3,3',4,4'-tetrahydro-4,4'-dimethyl-8,8'-bi(2H-1,4-benzoxazine)
4-(Dimethylamino)phenyldiphenylphosphine R-(+)-N,N'-Dimethyl-7,7'-bis(di(3,5-xylyl)phosphino)-3,3',4,4'-tetrahydro-8,8'-bi-2H-1,4-benzoxazine isopropanol adduct AURORA KA-1698 (R)-(-)-2,2'-Bis[di(3,5-di-i-propyl-4-dimethylaminophenyl)phosphino]-6,6'-dimethoxy-1,1'-biphenyl,min.97% AURORA KA-1605

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4-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLANILINE 4-(DIMETHYLAMINO)TRIPHENYLPHOSPHINE 4-(DIMETHYLAMINO)PHENYLDIPHENYLPHOSPHINE 95+% 4-(Diphenylphosphanyl)-N,N-dimethylaniline 4-(DiMethylaMino)phenyldiphenylphosphine SynonyMs 4-(Diphenylphosphanyl)-N,N-diMethylaniline 4-(Dimethylamino)triphenylphosphine 4-(Diphenylphosphino)-N,N-dimethylaniline 4-(Diphenylphosphino)-N,N-dimethyl-benzenamine 4-(Dimethylamino)phenyldiphenylphosphine 95% Diphenyl[4-(N,N-dimethylamino)phenyl]phosphine Diphenyl[4-(N,N-dimethylamino)phenyl]phosphine, min. 95% 4-(Diphenylphosphanyl)-N,N-dimethylanil 4-(Dimethylamino)phenyldiphenylphosphine> Benzenamine, 4-(diphenylphosphino)-N,N-dimethyl- 4-(tetramethylamine) phenyldiphenylphosphine (Diphenylphosphino)-N,N-dimethylaniline TricyclohexylphosphoniuM 4-(Dimethylamino)phenyldiphenylphosphine 739-58-2 CH32NC6H4PC6H52 C20H20NP Phosphines (Mitsunobu Reaction) Mitsunobu Reaction Phosphorus Compounds Phosphine Ligands Catalysis and Inorganic Chemistry Achiral Phosphine Aryl Phosphine Mitsunobu Reaction Phosphine Ligands Phosphines (Mitsunobu Reaction) Synthetic Organic Chemistry