Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>GSK321

GSK321

GSK321 Structure
GSK321 structure
CAS No.
1816331-63-1
Chemical Name:
GSK321
Synonyms
GSK321;GSK-321 (GSK321;1H-Pyrazolo[4,3-c]pyridine-3-carboxamide, 1-[(4-fluorophenyl)methyl]-4,5,6,7-tetrahydro-N-[3-[(1S)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-, (7R)-
CBNumber:
CB13339889
Molecular Formula:
C28H28FN5O3
Molecular Weight:
501.55
MDL Number:
MFCD30533608
MOL File:
1816331-63-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-05 09:01:00
Request For Quotation

GSK321 Properties

Melting point >120°C (dec.)
Boiling point 704.2±60.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 12.26±0.70(Predicted)
color White to Pale Yellow

GSK321 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-G797305-5MG GSK 321 1816331-63-1 5mg $472 2026-06-03 Buy
TRC TRC-G797305-2.5MG GSK 321 1816331-63-1 2.5mg $281 2026-06-03 Buy
TRC TRC-G797305-1MG GSK 321 1816331-63-1 1mg $154 2026-06-03 Buy
Biosynth RXC33163 GSK 321 1816331-63-1 5mg $752 2026-06-05 Buy
Biosynth RXC33163 GSK 321 1816331-63-1 10mg $1203.1 2026-06-05 Buy
Product number Packaging Price Buy
TRC-G797305-5MG 5mg $472 Buy
TRC-G797305-2.5MG 2.5mg $281 Buy
TRC-G797305-1MG 1mg $154 Buy
RXC33163 5mg $752 Buy
RXC33163 10mg $1203.1 Buy

GSK321 Chemical Properties, Uses, Production

Uses

GSK 321 is a potent and selective IDH1 (isocitrate dehydrogenase 1) mutant inhibitor for the treatment of acute myeloid leukemia.

in vivo

GSK321 (150 mg/kg; i.p.; daily, for 15 d; male CD-1 mice with IDH1 mutant AML xenograft) reduces leukemic blasts in vivo[1].

Animal Model:Male CD-1 mice with IDH1 mutant AML xenograft[1]
Dosage:150 mg/kg
Administration:Intraperitoneal injection; daily, for 15 days
Result:Decreased in 2HG in IDH1-mutant AML cells. Decreased in the percentage of blast cells (SSClowCD45low/+) and a relative increase in mature lymphoid and granulocytic/monocytic cells.

GSK321 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK321 Suppliers

Global Suppliers ( 15)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Suzhou Chenrui Biotechnology Co. LTD 17625585511 1580084073@qq.com China 992 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2223443625@qq.com China 7998 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1246 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29982 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
LGC Science (Shanghai) Ltd. 17717235263 17717235263 offer.de@lgcgroup.com China 38135 58
Supplier Advantage
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Suzhou Chenrui Biotechnology Co. LTD 58
Hubei Kele Fine Chemical Co., Ltd 58
Beijing Biocreative Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
https://hanhongsci.com/ 58
Shanghai Amole Biotechnology Co., Ltd. 58
LGC Science (Shanghai) Ltd. 58

View Latest Price from GSK321 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GSK321 pictures 2026-08-01 GSK321
1816331-63-1
 $149.00 99.73% 10g TargetMol Chemicals Inc.
  • GSK321 pictures
  • GSK321
    1816331-63-1
  • $149.00
  • 99.73%
  • TargetMol Chemicals Inc.

GSK321 Spectrum

GSK321(1816331-63-1)1HNMR

1816331-63-1 (GSK321) Related Search:

1H-Pyrazolo[4,3-c]pyridine-3-carboxamide, 1-[(4-fluorophenyl)methyl]-4,5,6,7-tetrahydro-N-[3-[(1R)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-, (7S)- GSK321 GSK990 GSK864 1H-Pyrazolo[4,3-c]pyridine-3-carboxamide, 1-[(4-fluorophenyl)methyl]-4,5,6,7-tetrahydro-N-[3-[(1R)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-, (7R)-
1H-Pyrazolo[4,3-c]pyridine-3-carboxamide, 1-[(4-fluorophenyl)methyl]-4,5,6,7-tetrahydro-N-[3-[(1S)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-, (7S)-

1of2

GSK-321 (GSK321 GSK321 1H-Pyrazolo[4,3-c]pyridine-3-carboxamide, 1-[(4-fluorophenyl)methyl]-4,5,6,7-tetrahydro-N-[3-[(1S)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-, (7R)- 1816331-63-1 C28H28FN5O3